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Differentiating Alzheimer's disease (AD) patients from healthy controls (HCs) remains a challenge. The changes of protein level in cerebrospinal fluid (CSF) of AD patients have been reported in the literature. Macromolecules will hinder the…

神经元与认知 · 定量生物学 2023-02-27 Yingnan Xue , Min Wen , Qiong Ye

Diffusional kurtosis imaging (DKI) is a methodology for measuring the extent of non-Gaussian diffusion in biological tissue, which has shown great promise in clinical diagnosis, treatment planning and monitoring of many neurological…

图像与视频处理 · 电气工程与系统科学 2024-04-29 Megan E. Farquhar , Qianqian Yang , Viktor Vegh

The displacement distribution of a water molecular is characterized mathematically as Gaussianity without considering potential diffusion barriers and compartments. However, this is not true in real scenario: most biological tissues are…

统计计算 · 统计学 2015-07-27 Jia Liu

Diffusion models have advanced generative AI significantly in terms of editing and creating naturalistic images. However, efficiently improving generated image quality is still of paramount interest. In this context, we propose a generic…

计算机视觉与模式识别 · 计算机科学 2023-11-17 Aniket Roy , Maiterya Suin , Anshul Shah , Ketul Shah , Jiang Liu , Rama Chellappa

Diffusion kurtosis imaging is an extension of diffusion tensor imaging that provides scientifically and clinically valuable information about brain tissue microstructure but suffers from poor robustness to noise, especially in voxels…

Diffusion MRI measures of the human brain provide key insight into microstructural variations across individuals and into the impact of central nervous system diseases and disorders. One approach to extract information from diffusion…

医学物理 · 物理学 2022-01-19 Qianqian Yang , David C. Reutens , Viktor Vegh

Purpose: To develop and validate a phantom for diagnostic ultrasound (US) scanners by embedding targets in gel wax to determine the image uniformity, lateral and axial resolution, and diameter of a stainless-steel disc. Materials and…

We report on extensive molecular dynamics simulations on systems of soft spheres of functionality f, i.e. particles that are capable of bonding irreversibly with a maximum of f other particles. These bonds are randomly distributed…

软凝聚态物质 · 物理学 2007-05-23 D. C. Vernon , Michael Plischke , Bela Joos

Computer simulations were done of the mean square displacement (MSD) of tracer particles in colloidal gels formed by diffusion or reaction limited aggregation of hard spheres. The diffusion coefficient was found to be determined by the…

软凝聚态物质 · 物理学 2009-03-25 Sujin Babu , Jean Christophe Gimel , Taco Nicolai

Magnetic resonance imaging technique known as DWI (diffusion-weighted imaging) allows measurement of water diffusivity on a pixel basis for evaluating pathology throughout the body and is now routinely incorporated into many body MRI…

Biophysical modelling of diffusion MRI is necessary to provide specific microstructural tissue properties. However, estimating model parameters from data with limited diffusion gradient strength, such as clinical scanners, has proven…

医学物理 · 物理学 2019-03-21 Sune Nørhøj Jespersen , Jonas Lynge Olesen , Brian Hansen , Noam Shemesh

Microgels are often discussed as well-suited model system for soft colloids. In contrast to rigid spheres, the microgel volume and, coupled to this, the volume fraction in dispersion can be manipulated by external stimuli. This behavior is…

We have developed a microfluidic tool to measure the diffusion coefficient $D$ of solutes in an aqueous solution, by following the temporal relaxation of an initially steep concentration gradient in a microchannel. Our chip exploits…

软凝聚态物质 · 物理学 2022-08-23 Hoang-Thanh Nguyen , Anne Bouchaudy , Jean-Baptiste Salmon

Using molecular dynamic simulations we study a waterlike model confined between two fixed hydrophobic plates. The system is tested for density, diffusion and structural anomalous behavior and compared with the bulk results. Within the range…

化学物理 · 物理学 2013-03-06 Leandro Batirolla Krott , Marcia Cristina Bernardes Barbosa

A practical correction formula relating the self-diffusion coefficient of dense liquids from molecular dynamics simulations with periodic boundary conditions to the self-diffusion coefficient in the thermodynamic limit is discussed. This…

统计力学 · 物理学 2024-02-15 Sergey Khrapak

The enhancement of surface diffusion (DS) over the bulk (DV) in metallic glasses (MGs) is well documented and likely to strongly influence the properties of glasses grown by vapor deposition. Here, we use classical molecular dynamics…

材料科学 · 物理学 2021-08-20 Ajay Annamareddy , Yuhui Li , Lian Yu , Paul M. Voyles , Dane Morgan

We use theory and simulations to investigate the existence of amorphous glassy states in ultrasoft colloids. We combine the hyper-netted chain approximation with mode-coupling theory to study the dynamic phase diagram of soft repulsive…

软凝聚态物质 · 物理学 2010-12-16 Ludovic Berthier , Angel J. Moreno , Grzegorz Szamel

The low temperature properties of glass are distinct from those of crystals due to the presence of poorly understood low-energy excitations. The tunneling model proposes that these are atoms tunneling between nearby equilibria, forming…

介观与纳米尺度物理 · 物理学 2016-11-23 Andrew Fefferman , Ana Maldonado , Eddy Collin , Xiao Liu , Tom Metcalf , Glenn Jernigan

Hydrogels behave as viscoelastic soft solids and display a porous microstructure filled with water with typical amounts of 90\%~w/w or more. As such, these materials are highly sensitive to water loss through evaporation, which impacts…

软凝聚态物质 · 物理学 2016-09-30 Bosi Mao , Thibaut Divoux , Patrick Snabre

A variety of researchers have successfully obtained the parameters of low dimensional diffusion models using the data that comes out of atomistic simulations. This naturally raises a variety of questions about efficient estimation,…

统计力学 · 物理学 2015-11-06 Christopher P. Calderon
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