相关论文: Predicting Novel Tick Vectors of Zoonotic Disease
Around the globe, ticks are the culprit of transmitting a variety of bacterial, viral and parasitic diseases. The incidence of tick-borne diseases has drastically increased within the last decade, with annual cases of Lyme disease soaring…
Lyme disease is an infectious disease transmitted to humans by a bite from an infected Ixodes species (blacklegged ticks). It is one of the fastest growing vector-borne illness in North America and is expanding its geographic footprint.…
Globally, vector-borne diseases are increasing in distribution and frequency, affecting humans, domestic animals and livestock, and wildlife. Science-based management and prevention of these diseases requires a sound understanding of the…
The spread of tick-borne pathogens represents an important threat to human and animal health in many parts of Eurasia. Here, we analysed a 9-year time series of Ixodes ricinus ticks feeding on Apodemus flavicollis mice (main…
In this paper we describe the dynamics of a vector-borne relapsing disease, such as tick-borne relapsing fever, using the methods of compartmental models. After some motivation, model description, and a brief overview of the theory of…
We introduce a stochastic household model for vector-borne diseases, in particular as relevant to prominent vectors belonging to the Aedes genus and hence the Zika, chikungunya, and dengue viruses. In this model, vectors remain local to…
Predicting the spread of vector-borne diseases in response to incursions requires knowledge of both host and vector demographics in advance of an outbreak. Whereas host population data is typically available, for novel disease introductions…
Nowadays, Vector-Borne Diseases (VBDs) raise a severe threat for public health, accounting for a considerable amount of human illnesses. Recently, several surveillance plans have been put in place for limiting the spread of such diseases,…
Diagnostic tests that can detect pre-clinical or sub-clinical infection, are one of the most powerful tools in our armoury of weapons to control infectious diseases. Considerable effort has been paid to improving diagnostic testing for…
Viral zoonoses have emerged as the key drivers of recent pandemics. Human infection by zoonotic viruses are either spillover events -- isolated infections that fail to cause a widespread contagion -- or species jumps, where successful…
A class of stochastic vector-borne infectious disease models is derived and studied. The class type is determined by a general nonlinear incidence rate of the disease. The disease spreads in a highly random environment with variability from…
Identifying areas in a landscape where individuals have a higher likelihood of disease infection is key to managing diseases. Unlike conventional methods relying on ecological assumptions, we perform a novel epidemiological tomography for…
Mosquito-borne diseases cause significant public health burden, mostly in tropical and sub-tropical regions, and are widely emerging or re-emerging in areas where previously absent. Understanding, predicting, and mitigating the spread of…
Among all animals, mosquitoes are responsible for the most deaths worldwide. Interestingly, not all types of mosquitoes spread diseases, but rather, a select few alone are competent enough to do so. In the case of any disease outbreak, an…
It is possible to model vector-borne infection using the classical Ross-Macdonald model. This attempt, however fails in several respects. First, using measured (or estimated) parameters, the model predicts a much greater number of cases…
Infectious zoonotic disease emergence, through spillover events, is of global concern and has the potential to cause significant harm to society, as recently demonstrated by COVID-19. More than 70% of the 400 infectious diseases that…
Aedes Aegypti is the vector of several deadly diseases, including Zika. Effective and sustainable vector control measures must be deployed to keep A. aegypti numbers under control. The distribution of A. Aegypti is subject to spatial and…
Inferring concerted changes among biological traits along an evolutionary history remains an important yet challenging problem. Besides adjusting for spurious correlation induced from the shared history, the task also requires sufficient…
Spirochetes belonging to the Borrelia burgdoferi sensu lato (sl) group cause Lyme Borreliosis (LB), which is the most commonly reported vector-borne zoonosis in Europe. B. burgdorferi sl is maintained in nature in a complex cycle involving…
The emergence or adaptation of pathogens may lead to epidemics, highlighting the need for a thorough understanding of pathogen evolution. The tradeoff hypothesis suggests that virulence evolves to reach an optimal transmission intensity…