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Artificial Intelligence has emerged as a useful aid in numerous clinical applications for diagnosis and treatment decisions. Deep neural networks have shown same or better performance than clinicians in many tasks owing to the rapid…

图像与视频处理 · 电气工程与系统科学 2021-11-05 Zohaib Salahuddin , Henry C Woodruff , Avishek Chatterjee , Philippe Lambin

We present an interpretable companion model for any pre-trained black-box classifiers. The idea is that for any input, a user can decide to either receive a prediction from the black-box model, with high accuracy but no explanations, or…

机器学习 · 统计学 2020-02-12 Danqing Pan , Tong Wang , Satoshi Hara

Recent efforts in Machine Learning (ML) interpretability have focused on creating methods for explaining black-box ML models. However, these methods rely on the assumption that simple approximations, such as linear models or decision-trees,…

机器学习 · 计算机科学 2019-06-13 Owen Lahav , Nicholas Mastronarde , Mihaela van der Schaar

Within diagnostic reasoning there have been a number of proposed definitions of a diagnosis, and thus of the most likely diagnosis, including most probable posterior hypothesis, most probable interpretation, most probable covering…

人工智能 · 计算机科学 2013-04-05 David L. Poole , Gregory M. Provan

Machine-learning models are ubiquitous. In some domains, for instance, in medicine, the models' predictions must be interpretable. Decision trees, classification rules, and subgroup discovery are three broad categories of supervised…

机器学习 · 计算机科学 2022-04-29 Vadim Arzamasov , Benjamin Jochum , Klemens Böhm

When we deploy machine learning models in high-stakes medical settings, we must ensure these models make accurate predictions that are consistent with known medical science. Inherently interpretable networks address this need by explaining…

计算机视觉与模式识别 · 计算机科学 2021-10-06 Alina Jade Barnett , Fides Regina Schwartz , Chaofan Tao , Chaofan Chen , Yinhao Ren , Joseph Y. Lo , Cynthia Rudin

We introduce an algorithm for identifying interpretable subgroups with elevated treatment effects, given an estimate of individual or conditional average treatment effects (CATE). Subgroups are characterized by ``rule sets'' --…

机器学习 · 统计学 2025-07-15 Albert Chiu

We introduce Matched Machine Learning, a framework that combines the flexibility of machine learning black boxes with the interpretability of matching, a longstanding tool in observational causal inference. Interpretability is paramount in…

统计方法学 · 统计学 2023-04-05 Marco Morucci , Cynthia Rudin , Alexander Volfovsky

Recent development in the data-driven decision science has seen great advances in individualized decision making. Given data with individual covariates, treatment assignments and outcomes, policy makers best individualized treatment rule…

机器学习 · 统计学 2020-06-29 Weibin Mo , Zhengling Qi , Yufeng Liu

Adaptive designs are commonly used in clinical and drug development studies for optimum utilization of available resources. In this article, we consider the problem of estimating the effect of the selected (better) treatment using a…

统计理论 · 数学 2023-01-24 Masihuddin , Neeraj Misra

In many applied optimization settings, parameters that define the constraints may not guarantee the best possible solution, and superior solutions might exist that are infeasible for the given parameter values. Removing such constraints,…

最优化与控制 · 数学 2024-07-22 Farzin Ahmadi , Todd R. McNutt , Kimia Ghobadi

This paper describes methods for comparative evaluation of the interpretability of models of high dimensional time series data inferred by unsupervised machine learning algorithms. The time series data used in this investigation were logs…

人工智能 · 计算机科学 2020-05-05 Nicholas Hoernle , Kobi Gal , Barbara Grosz , Leilah Lyons , Ada Ren , Andee Rubin

The goal of personalized decision making is to map a unit's characteristics to an action tailored to maximize the expected outcome for that unit. Obtaining high-quality mappings of this type is the goal of the dynamic regime literature. In…

机器学习 · 计算机科学 2018-10-01 Razieh Nabi , Phyllis Kanki , Ilya Shpitser

Digital health interventions (DHIs) and remote patient monitoring (RPM) have shown great potential in improving chronic disease management through personalized care. However, barriers like limited efficacy and workload concerns hinder…

机器学习 · 计算机科学 2025-12-23 Johannes O. Ferstad , Emily B. Fox , David Scheinker , Ramesh Johari

As machine learning algorithms getting adopted in an ever-increasing number of applications, interpretation has emerged as a crucial desideratum. In this paper, we propose a mathematical definition for the human-interpretable model. In…

机器学习 · 计算机科学 2021-06-01 Weishen Pan , Changshui Zhang

A/B testing is critical for modern technological companies to evaluate the effectiveness of newly developed products against standard baselines. This paper studies optimal designs that aim to maximize the amount of information obtained from…

统计方法学 · 统计学 2023-11-07 Ting Li , Chengchun Shi , Jianing Wang , Fan Zhou , Hongtu Zhu

When making treatment selection decisions, it is essential to include a causal effect estimation analysis to compare potential outcomes under different treatments or controls, assisting in optimal selection. However, merely estimating…

机器学习 · 统计学 2024-10-08 Sherly Alfonso-Sánchez , Kristina P. Sendova , Cristián Bravo

Individualized treatment rules (ITRs) are considered a promising recipe to deliver better policy interventions. One key ingredient in optimal ITR estimation problems is to estimate the average treatment effect conditional on a subject's…

统计方法学 · 统计学 2021-03-16 Hongming Pu , Bo Zhang

Interpretable representations are the backbone of many explainers that target black-box predictive systems based on artificial intelligence and machine learning algorithms. They translate the low-level data representation necessary for good…

机器学习 · 计算机科学 2024-04-29 Kacper Sokol , Peter Flach

We consider the problem of learning an optimal prescriptive tree (i.e., an interpretable treatment assignment policy in the form of a binary tree) of moderate depth, from observational data. This problem arises in numerous socially…

机器学习 · 计算机科学 2023-07-25 Nathanael Jo , Sina Aghaei , Andrés Gómez , Phebe Vayanos