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High-fidelity electron microscopy simulations required for quantitative crystal structure refinements face a fundamental challenge: while physical interactions are well-described theoretically, real-world experimental effects are…

Collisions at high-energy particle colliders are a traditionally fruitful source of exotic particle discoveries. Finding these rare particles requires solving difficult signal-versus-background classification problems, hence machine…

高能物理 - 唯象学 · 物理学 2015-06-18 Pierre Baldi , Peter Sadowski , Daniel Whiteson

With the growing amount of astronomical data, there is an increasing need for automated data processing pipelines, which can extract scientific information from observation data without human interventions. A critical aspect of these…

天体物理仪器与方法 · 物理学 2024-05-07 Peng Jia , Yu Song , Jiameng Lv , Runyu Ning

We present a deep learning, computer vision algorithm constructed for the purposes of identifying and classifying charged particles in camera image sensors. We apply our algorithm to data collected by the Distributed Electronic Cosmic-ray…

We show that de-focused single particle images recorded using a cryo-electron microscope (cryoEM) system may be processed like a Fresnel zone in-line hologram to obtain physically meaningful quantitative phase maps associated with…

图像与视频处理 · 电气工程与系统科学 2021-11-24 Apoorv Pant , Manidipa Banerjee , Kedar Khare

Intense short-wavelength pulses from free-electron lasers and high-harmonic-generation sources enable diffractive imaging of individual nano-sized objects with a single x-ray laser shot. The enormous data sets with up to several million…

We present a machine-learning-based particle-identification study for the proximity-focusing Ring Imaging Cherenkov (pfRICH) detector of the ePIC experiment at the Electron-Ion Collider. Operating in the backward region ($-3.5 \lesssim \eta…

仪器与探测器 · 物理学 2025-12-30 D. H. Dongwi , C. -J. Naïm , L. Rhode , A. Deshpande

Human parsing aims to partition humans in image or video into multiple pixel-level semantic parts. In the last decade, it has gained significantly increased interest in the computer vision community and has been utilized in a broad range of…

计算机视觉与模式识别 · 计算机科学 2024-03-15 Lu Yang , Wenhe Jia , Shan Li , Qing Song

The recent improvements in cryo-electron microscopy (cryo-EM) in the past few years are now allowing to observe molecular complexes at atomic resolution. As a consequence, numerous structures derived from cryo-EM are now available in the…

生物大分子 · 定量生物学 2020-05-04 Mikael Trellet , Gydo van Zundert , Alexandre M. J. J. Bonvin

As a promising framework for resolving partial differential equations (PDEs), Physics-Informed Neural Networks (PINNs) have received widespread attention from industrial and scientific fields. However, lack of expressive ability and…

机器学习 · 计算机科学 2024-09-13 Feilong Jiang , Xiaonan Hou , Min Xia

Multiple approaches to use deep learning for image restoration have recently been proposed. Training such approaches requires well registered pairs of high and low quality images. While this is easily achievable for many imaging modalities,…

计算机视觉与模式识别 · 计算机科学 2024-10-30 Tim-Oliver Buchholz , Mareike Jordan , Gaia Pigino , Florian Jug

Cryo-electron microscopy (Cryo-EM) enables high-resolution imaging of biomolecules, but structural heterogeneity remains a major challenge in 3D reconstruction. Traditional methods assume a discrete set of conformations, limiting their…

机器学习 · 统计学 2025-09-09 Diego Sanchez Espinosa , Erik H Thiede , Yunan Yang

Educational Process Mining (EPM) is a data analysis technique that is used to improve educational processes. It is based on Process Mining (PM), which involves gathering records (logs) of events to discover process models and analyze the…

数据库 · 计算机科学 2025-06-27 Daniel Calegari , Andrea Delgado

Cryo-electron microscopy (cryo-EM) has recently emerged as a powerful tool for obtaining three-dimensional (3D) structures of biological macromolecules in native states. A minimum cryo-EM image data set for deriving a meaningful…

应用统计 · 统计学 2014-04-28 Ting-Li Chen , Dai-Ni Hsieh , Hung Hung , I-Ping Tu , Pei-Shien Wu , Yi-Ming Wu , Wei-Hau Chang , Su-Yun Huang

Metaproteomics are becoming widely used in microbiome research for gaining insights into the functional state of the microbial community. Current metaproteomics studies are generally based on high-throughput tandem mass spectrometry (MS/MS)…

定量方法 · 定量生物学 2020-09-24 Xuan Guo , Shichao Feng

In the domain of battery research, the processing of high-resolution microscopy images is a challenging task, as it involves dealing with complex images and requires a prior understanding of the components involved. The utilization of deep…

计算机视觉与模式识别 · 计算机科学 2025-03-19 Ganesh Raghavendran , Bing Han , Fortune Adekogbe , Shuang Bai , Bingyu Lu , William Wu , Minghao Zhang , Ying Shirley Meng

In order to achieve state-of-the-art performance, modern machine learning techniques require careful data pre-processing and hyperparameter tuning. Moreover, given the ever increasing number of machine learning models being developed, model…

机器学习 · 统计学 2018-05-03 Nicolo Fusi , Rishit Sheth , Huseyn Melih Elibol

Structural dynamics of macromolecules is critical to their structural-function relationship. Cryogenic electron microscopy (CryoEM) provides snapshots of vitrified protein at different compositional and conformational states, and the…

定量方法 · 定量生物学 2026-01-27 Muyuan Chen , Muchen Li , Renjie Liao

We are now witnessing significant progress of deep learning methods in a variety of tasks (or datasets) of proteins. However, there is a lack of a standard benchmark to evaluate the performance of different methods, which hinders the…

机器学习 · 计算机科学 2022-09-20 Minghao Xu , Zuobai Zhang , Jiarui Lu , Zhaocheng Zhu , Yangtian Zhang , Chang Ma , Runcheng Liu , Jian Tang