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Often in machine learning, data are collected as a combination of multiple conditions, e.g., the voice recordings of multiple persons, each labeled with an ID. How could we build a model that captures the latent information related to these…

机器学习 · 统计学 2017-05-30 Zhenwen Dai , Mauricio A. Álvarez , Neil D. Lawrence

Latent dynamics discovery is challenging in extracting complex dynamics from high-dimensional noisy neural data. Many dimensionality reduction methods have been widely adopted to extract low-dimensional, smooth and time-evolving latent…

机器学习 · 计算机科学 2019-07-02 Qi She , Anqi Wu

Understanding how the collective activity of neural populations relates to computation and ultimately behavior is a key goal in neuroscience. To this end, statistical methods which describe high-dimensional neural time series in terms of…

神经元与认知 · 定量生物学 2025-01-14 Amber Hu , David Zoltowski , Aditya Nair , David Anderson , Lea Duncker , Scott Linderman

Clinical patient records are an example of high-dimensional data that is typically collected from disparate sources and comprises of multiple likelihoods with noisy as well as missing values. In this work, we propose an unsupervised…

机器学习 · 统计学 2021-04-21 Siddharth Ramchandran , Miika Koskinen , Harri Lähdesmäki

We introduce a novel stochastic variational inference method for Gaussian process ($\mathcal{GP}$) regression, by deriving a posterior over a learnable set of coresets: i.e., over pseudo-input/output, weighted pairs. Unlike former free-form…

机器学习 · 计算机科学 2025-03-06 Mert Ketenci , Adler Perotte , Noémie Elhadad , Iñigo Urteaga

Neural circuits contain heterogeneous groups of neurons that differ in type, location, connectivity, and basic response properties. However, traditional methods for dimensionality reduction and clustering are ill-suited to recovering the…

机器学习 · 统计学 2016-10-27 Scott W. Linderman , Ryan P. Adams , Jonathan W. Pillow

Single-cell RNA sequencing provides insights into gene expression at single-cell resolution, yet inferring temporal processes from these static snapshot measurements remains a fundamental challenge. Current approaches utilizing neural…

机器学习 · 计算机科学 2026-05-21 Mehmet Yigit Balik , Harri Lähdesmäki

Latent Gaussian process (GP) models are widely used in neuroscience to uncover hidden state evolutions from sequential observations, mainly in neural activity recordings. While latent GP models provide a principled and powerful solution in…

神经元与认知 · 定量生物学 2023-06-06 Matthew Dowling , Yuan Zhao , Il Memming Park

Scientific and engineering problems often require the use of artificial intelligence to aid understanding and the search for promising designs. While Gaussian processes (GP) stand out as easy-to-use and interpretable learners, they have…

机器学习 · 计算机科学 2021-07-01 Liwei Wang , Suraj Yerramilli , Akshay Iyer , Daniel Apley , Ping Zhu , Wei Chen

Gaussian processes (GPs) are popular nonparametric statistical models for learning unknown functions and quantifying the spatiotemporal uncertainty in data. Recent works have extended GPs to model scalar and vector quantities distributed…

Heteroscedastic regression considering the varying noises among observations has many applications in the fields like machine learning and statistics. Here we focus on the heteroscedastic Gaussian process (HGP) regression which integrates…

机器学习 · 统计学 2020-01-22 Haitao Liu , Yew-Soon Ong , Jianfei Cai

The Gaussian process latent variable model (GP-LVM) is a popular approach to non-linear probabilistic dimensionality reduction. One design choice for the model is the number of latent variables. We present a spike and slab prior for the…

机器学习 · 统计学 2015-05-12 Zhenwen Dai , James Hensman , Neil Lawrence

For a learning task, Gaussian process (GP) is interested in learning the statistical relationship between inputs and outputs, since it offers not only the prediction mean but also the associated variability. The vanilla GP however struggles…

机器学习 · 统计学 2020-09-01 Haitao Liu , Yew-Soon Ong , Xiaomo Jiang , Xiaofang Wang

We develop an automated variational method for inference in models with Gaussian process (GP) priors and general likelihoods. The method supports multiple outputs and multiple latent functions and does not require detailed knowledge of the…

机器学习 · 统计学 2018-11-06 Edwin V. Bonilla , Karl Krauth , Amir Dezfouli

The Gaussian process latent variable model (GP-LVM) provides a flexible approach for non-linear dimensionality reduction that has been widely applied. However, the current approach for training GP-LVMs is based on maximum likelihood, where…

机器学习 · 统计学 2014-09-09 Andreas C. Damianou , Michalis K. Titsias , Neil D. Lawrence

In many clinical trials treatments need to be repeatedly applied as diseases relapse frequently after remission over a long period of time (e.g., 35 weeks). Most research in statistics focuses on the overall trial design, such as sample…

统计方法学 · 统计学 2014-04-01 Yanxun Xu , Yuan Ji

We propose a probabilistic framework for developing computational models of biological neural systems. In this framework, physiological recordings are viewed as discrete-time partial observations of an underlying continuous-time stochastic…

神经元与认知 · 定量生物学 2026-02-10 Ahmed ElGazzar , Marcel van Gerven

We study the estimation of the latent variable Gaussian graphical model (LVGGM), where the precision matrix is the superposition of a sparse matrix and a low-rank matrix. In order to speed up the estimation of the sparse plus low-rank…

机器学习 · 统计学 2017-03-01 Pan Xu , Jian Ma , Quanquan Gu

Variational inference is a powerful tool for approximate inference, and it has been recently applied for representation learning with deep generative models. We develop the variational Gaussian process (VGP), a Bayesian nonparametric…

机器学习 · 统计学 2016-04-19 Dustin Tran , Rajesh Ranganath , David M. Blei

We study the Gaussian Process regression model in the context of training data with noise in both input and output. The presence of two sources of noise makes the task of learning accurate predictive models extremely challenging. However,…

机器学习 · 统计学 2015-07-03 Cuong Tran , Vladimir Pavlovic , Robert Kopp
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