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相关论文: White-light Quantitative Phase Imaging Unit

200 篇论文

This paper reported a general noninterferometric high-accuracy quantitative phase imaging (QPI) method for arbitrary complex valued objects. Given by a typical 4f optical configuration as the imaging system, three frames of small-window…

图像与视频处理 · 电气工程与系统科学 2021-05-05 Jianhui Huang , An Pan , Huiliang Jin , Guoxiang Meng , Qian Ye

Tissue biopsy evaluation in the clinic is in need of quantitative disease markers for diagnosis and, most importantly, prognosis. Among the new technologies, quantitative phase imaging (QPI) has demonstrated promise for histopathology…

Quantitative phase microscopy (QPM) has found significant applications in the field of biomedical imaging which works on the principle of interferometry. The theory behind achieving interference in QPM with conventional light sources such…

光学 · 物理学 2021-07-26 Azeem Ahmad , Nikhil Jayakumar , Balpreet Singh Ahluwalia

With applications ranging from metabolomics to histopathology, quantitative phase microscopy (QPM) is a powerful label-free imaging modality. Despite significant advances in fast multiplexed imaging sensors and deep-learning-based inverse…

Label-free optical imaging is valuable in biology and medicine with its non-destructive property and reduced optical and chemical damages. Quantitative phase (QPI) and molecular vibrational imaging (MVI) are the two most successful…

Quantitative phase imaging (QPI) has been widely applied in characterizing cells and tissues. Spatial light interference microscopy (SLIM) is a highly sensitive QPI method, due to its partially coherent illumination and common path…

图像与视频处理 · 电气工程与系统科学 2024-06-12 Yuheng Jiao , Yuchen R. He , Mikhail E. Kandel , Xiaojun Liu , Wenlong Lu , Gabriel Popescu

Multi-spectral quantitative phase imaging (QPI) is an emerging imaging modality for wavelength dependent studies of several biological and industrial specimens. Simultaneous multi-spectral QPI is generally performed with color CCD cameras.…

仪器与探测器 · 物理学 2019-02-20 Azeem Ahmad , Anand Kumar , Vishesh Dubey , Ankit Butola , Balpreet Singh Ahluwalia , Dalip Singh Mehta

Quantitative phase imaging (QPI) through multi-core fibers (MCFs) has been an emerging in vivo label-free endoscopic imaging modality with minimal invasiveness. However, the computational demands of conventional iterative phase retrieval…

In this paper, we review spatial light interference microscopy (SLIM), a common-path, phase-shifting interferometer, built onto a phase-contrast microscope, with white-light illumination. As one of the most sensitive quantitative phase…

光学 · 物理学 2020-12-17 Xi Chen , Mikhail E. Kandel , Gabriel Popescu

Due to its specificity, fluorescence microscopy (FM) has become a quintessential imaging tool in cell biology. However, photobleaching, phototoxicity, and related artifacts continue to limit FM's utility. Recently, it has been shown that…

We present a powerful and cost-effective method for active illumination using a digital micromirror device (DMD) for quantitative phase imaging techniques. Displaying binary illumination patterns on a DMD with appropriate spatial filtering,…

光学 · 物理学 2023-07-19 Seungwoo Shin , Kyoohyun Kim , Jonghee Yoon , YongKeun Park

The health of cells found in the inner retinal layers of the human eye is crucial to understand the onset of diseases of the retina such as macular degeneration and retinopathy. A challenge is to periodically image these cells in human eyes…

Measuring the average refractive index (RI) of spherical objects, such as suspended cells, in quantitative phase imaging (QPI) requires a decoupling of RI and size from the QPI data. This has been commonly achieved by determining the…

定量方法 · 定量生物学 2018-04-27 Paul Müller , Mirjam Schürmann , Salvatore Girardo , Gheorghe Cojoc , Jochen Guck

Using a deep neural network, we demonstrate a digital staining technique, which we term PhaseStain, to transform quantitative phase images (QPI) of labelfree tissue sections into images that are equivalent to brightfield microscopy images…

图像与视频处理 · 电气工程与系统科学 2019-02-08 Yair Rivenson , Tairan Liu , Zhensong Wei , Yibo Zhang , Aydogan Ozcan

A major hurdle in Quantum Image Processing (QIMP) is efficiently transferring classical, high-dimensional image data into quantum states. Current methods face trade-offs: amplitude encoding (FRQI) is computationally expensive in gate…

Vibrational micro-spectroscopy is a powerful optical tool, providing a non-invasive label-free chemically specific imaging for many chemical and biomedical applications. However, hyperspectral image produced by Raman micro-spectroscopy…

计算物理 · 物理学 2019-03-12 E. G. Lobanova , S. V. Lobanov

White light interferometry (WLI) can be used to obtain surface morphology information on dimensional scale of millimeters with lateral resolution as good as ~1 {\mu}m and depth resolution down to 1 nm. By performing true three-dimensional…

材料科学 · 物理学 2012-04-05 S. V. Baryshev , A. V. Zinovev , C. E. Tripa , R. A. Erck , I. V. Veryovkin

Quantitative phase microscopy (QPM) is often based on recording an object-reference interference pattern and its further phase demodulation. We propose Pseudo Hilbert Phase Microscopy (PHPM) where we combine pseudo thermal light source…

Quantum illumination (QI) is an entanglement-based protocol for improving lidar/radar detection of unresolved targets beyond what a classical lidar/radar of the same average transmitted energy can do. Originally proposed by Lloyd as a…

量子物理 · 物理学 2024-09-20 Jeffrey H. Shapiro

Quantitative phase microscopy (QPM), a technique combining phase imaging and microscopy, enables visualization of the 3D topography in reflective samples, as well as the inner structure or refractive index distribution of transparent and…

光学 · 物理学 2025-01-17 Vicente Mico , Juanjuan Zheng , Javier Garcia , Zeev Zalevsky , Peng Gao