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Reconciling a gene tree with a species tree is an important task that reveals much about the evolution of genes, genomes, and species, as well as about the molecular function of genes. A wide array of computational tools have been devised…

种群与进化 · 定量生物学 2012-12-11 Yun Yu , Luay Nakhleh

The deterministic selection-recombination equation describes the evolution of the genetic type composition of a population under selection and recombination in a law of large numbers regime. So far, an explicit solution has seemed out of…

概率论 · 数学 2023-04-26 Ellen Baake , Frederic Alberti

The alignment of biological sequences such as DNA, RNA, and proteins, is one of the basic tools that allow to detect evolutionary patterns, as well as functional/structural characterizations between homologous sequences in different…

定量方法 · 定量生物学 2023-05-01 Louise Budzynski , Andrea Pagnani

Despite the recent progress in genome sequencing and assembly, many of the currently available assembled genomes come in a draft form. Such draft genomes consist of a large number of genomic fragments (scaffolds), whose order and/or…

基因组学 · 定量生物学 2022-05-27 Sergey Aganezov , Pavel Avdeyev , Nikita Alexeev , Yongwu Rong , Max A. Alekseyev

Recently, there emerged revived interests of designing automatic programs (e.g., using genetic/evolutionary algorithms) to optimize the structure of Convolutional Neural Networks (CNNs) for a specific task. The challenge in designing such…

神经与进化计算 · 计算机科学 2018-06-05 Zhe Li , Xuehan Xiong , Zhou Ren , Ning Zhang , Xiaoyu Wang , Tianbao Yang

This paper investigates the influence of genotype size on evolutionary algorithms' performance. We consider genotype compression (where genotype is smaller than phenotype) and expansion (genotype is larger than phenotype) and define…

神经与进化计算 · 计算机科学 2021-05-26 Lucija Planinic , Marko Djurasevic , Luca Mariot , Domagoj Jakobovic , Stjepan Picek , Carlos Coello Coello

Technical signs of progress during the last decades has led to a situation in which the accumulation of genome sequence data is increasingly fast and cheap. The huge amount of molecular data available nowadays can help addressing new and…

基因组学 · 定量生物学 2017-05-02 Christophe Guyeux , Bashar Al-Nuaimi , Bassam AlKindy , Jean-François Couchot , Michel Salomon

This paper is devoted to proposing a general weighted low-rank recovery model and designing a fast SVD-free computational scheme to solve it. First, our generic weighted low-rank recovery model unifies several existing approaches in the…

最优化与控制 · 数学 2022-08-02 Aritra Dutta , Jingwei Liang , Xin Li

We wish to minimize the resources used for network coding while achieving the desired throughput in a multicast scenario. We employ evolutionary approaches, based on a genetic algorithm, that avoid the computational complexity that makes…

网络与互联网体系结构 · 计算机科学 2016-11-15 Minkyu Kim , Muriel Medard , Varun Aggarwal , Una-May O'Reilly , Wonsik Kim , Chang Wook Ahn , Michelle Effros

This paper presents a new type of genetic algorithm for the set covering problem. It differs from previous evolutionary approaches first because it is an indirect algorithm, i.e. the actual solutions are found by an external decoder…

神经与进化计算 · 计算机科学 2010-07-05 Uwe Aickelin

We extend the standard rough set-based approach to deal with huge amounts of numeric attributes versus small amount of available objects. Here, a novel approach of clustering along with dimensionality reduction; Hybrid Fuzzy C Means-Quick…

计算工程、金融与科学 · 计算机科学 2013-06-11 E. N. Sathishkumar , K. Thangavel , T. Chandrasekhar

This paper introduces constNJ, the first algorithm for phylogenetic reconstruction of sets of trees with constrained pairwise rooted subtree-prune regraft (rSPR) distance. We are motivated by the problem of constructing sets of trees which…

种群与进化 · 定量生物学 2009-09-30 Frederick A. Matsen

The maximum parsimony phylogenetic tree reconstruction problem is NP-hard, presenting a computational bottleneck for classical computing and motivating the exploration of emerging paradigms like quantum computing. To this end, we design…

量子物理 · 物理学 2026-04-20 Jiawei Zhang , Yibo Chen , Yang Zhou , Jun-Han Huang

The 0-1 knapsack problem is a well-known combinatorial optimisation problem. Approximation algorithms have been designed for solving it and they return provably good solutions within polynomial time. On the other hand, genetic algorithms…

神经与进化计算 · 计算机科学 2014-04-04 Jun He , Feidun He , Hongbin Dong

Motivation: Millions of genes in the modern species belong to only thousands of `gene families'. A gene family includes instances of the same gene in different species (orthologs) and duplicate genes in the same species (paralogs). Genes…

种群与进化 · 定量生物学 2012-05-04 Yu Zheng , Taoyang Wu , Louxin Zhang

An implementation and an application of the combination of the genetic algorithm and Newton's method for solving a system of nonlinear equations is presented. The method first uses the advantage of the robustness of the genetic algorithm…

数值分析 · 数学 2020-07-13 Ryuji Koshikawa , Akira Terui , Masahiko Mikawa

Theoretical studies on evolutionary algorithms have developed vigorously in recent years. Many such algorithms have theoretical guarantees in both running time and approximation ratio. Some approximation mechanism seems to be inherently…

神经与进化计算 · 计算机科学 2022-10-04 Yaoyao Zhang , Chaojie Zhu , Shaojie Tang , Ringli Ran , Ding-Zhu Du , Zhao Zhang

This thesis investigates the use of problem-specific knowledge to enhance a genetic algorithm approach to multiple-choice optimisation problems.It shows that such information can significantly enhance performance, but that the choice of…

神经与进化计算 · 计算机科学 2010-07-05 Uwe Aickelin

Self-adaptation solutions need to periodically monitor, reason about, and adapt a running system. The adaptation step involves generating an adaptation strategy and applying it to the running system whenever an anomaly arises. In this…

软件工程 · 计算机科学 2023-08-16 Jia Li , Shiva Nejati , Mehrdad Sabetzadeh

Genome rearrangement distances are an established method in genome comparison. Works in this area may include various rearrangement operations representing large-scale mutations, gene orientation information, the number of nucleotides in…

数据结构与算法 · 计算机科学 2026-01-01 Gabriel Siqueira , Alexsandro Oliveira Alexandrino , Zanoni Dias