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The exchange of small molecular signals within microbial populations is generally referred to as quorum sensing (QS). QS is ubiquitous in nature and enables microorganisms to respond to fluctuations in living environments by working…

细胞行为 · 定量生物学 2019-09-16 Yuting Fang , Adam Noel , Andrew W. Eckford , Nan Yang

In quorum sensing (QS), bacteria exchange molecular signals to work together. An analytically-tractable model is presented for characterizing QS signal propagation within a population of bacteria and the number of responsive cooperative…

信息论 · 计算机科学 2020-09-03 Yuting Fang , Adam Noel , Andrew W. Eckford , Nan Yang , Jing Guo

Microorganisms employ sophisticated mechanisms for intercellular communication and environmental sensing, with quorum sensing serving as a fundamental regulatory process. Dysregulation of quorum sensing has been implicated in various…

新兴技术 · 计算机科学 2025-09-30 O. Tansel Baydas , Efe Yatgin , Ozgur B. Akan

Quorum sensing is a decentralized biological process, through which a community of cells with no global awareness coordinate their functional behaviors based solely on cell-medium interactions and local decisions. This paper draws…

机器学习 · 计算机科学 2015-10-08 Feng Tan , Jean-Jacques Slotine

Microbial communities frequently communicate via quorum sensing (QS), where cells produce, secrete, and respond to a threshold level of an autoinducer (AI) molecule, thereby modulating gene expression. However, the biology of QS remains…

分子网络 · 定量生物学 2017-08-02 Tahir Yusufaly , James Q. Boedicker

Quorum sensing is the regulation of gene expression in response to changes in cell density. To measure their cell density, bacterial populations produce and detect diffusible molecules called autoinducers. Individual bacteria internally…

分子网络 · 定量生物学 2017-04-12 Thibaud Taillefumier , Ned S. Wingreen

Microbial communities play a significant role in bioremediation,plant growth,human and animal digestion,global elemental cycles including the carbon-cycle,and water treatment.They are also posed to be the engines of renewable energy via…

新兴技术 · 计算机科学 2016-01-12 Nicolò Michelusi , James Boedicker , Mohamed Y. El-Naggar , Urbashi Mitra

Bacteria communicate using secreted chemical signaling molecules called autoinducers in a process known as quorum sensing. The quorum-sensing network of the marine bacterium {\it Vibrio harveyi} employs three autoinducers, each known to…

分子网络 · 定量生物学 2009-05-27 Pankaj Mehta , Sidhartha Goyal , Tao Long , Bonnie Bassler , Ned S. Wingreen

We study the role of Quorum Sensing (QS) in the growth of bacterial colonies and in the bioluminescence produced. These two phenomena are both regulated by QS and the experimental data show a non-trivial correlation between them. It is also…

生物物理 · 物理学 2023-10-27 E. Alfinito , M. Beccaria , M. Cesaria

In many natural synchronization phenomena, communication between individual elements occurs not directly, but rather through the environment. One of these instances is bacterial quorum sensing, where bacteria release signaling molecules in…

动力系统 · 数学 2015-05-18 Giovanni Russo , Jean-Jacques E. Slotine

Within the context of evolution, an altruistic act that benefits the receiving individual at the expense of the acting individual is a puzzling phenomenon. An extreme form of altruism can be found in colicinogenic E. coli. These suicidal…

神经与进化计算 · 计算机科学 2016-03-31 Anya Elaine Johnson , Eli Strauss , Rodney Pickett , Christoph Adami , Ian Dworkin , Heather J. Goldsby

Autoinducers are small signaling molecules that mediate intercellular communication in microbial populations and trigger coordinated gene expression via "quorum sensing". Elucidating the mechanisms that control autoinducer production is,…

种群与进化 · 定量生物学 2017-07-26 Matthias Bauer , Johannes Knebel , Matthias Lechner , Peter Pickl , Erwin Frey

We propose a model for bacterial Quorum Sensing based on an auxiliary electrostatic-like interac-tion originating from a fictitious electrical charge that represents bacteria activity. A cooperative mechanism for charge/activity exchange is…

生物物理 · 物理学 2023-02-22 Eleonora Alfinito , Maura Cesaria , Matteo Beccaria

Bacteria populations rely on mechanisms such as quorum sensing to coordinate complex tasks that cannot be achieved by a single bacterium. Quorum sensing is used to measure the local bacteria population density, and it controls cooperation…

细胞行为 · 定量生物学 2018-02-14 Adam Noel , Yuting Fang , Nan Yang , Dimitrios Makrakis , Andrew W. Eckford

A cooperative drug delivery system is proposed, where quorum sensing (QS), a density-dependent bacterial behavior coordination mechanism, is employed by synthetic bacterium-based nanomachines (B-NMs) for controllable drug delivery. In our…

定量方法 · 定量生物学 2023-03-15 Yuting Fang , Stuart T. Johnston , Matt Faria , Xinyu Huang , Andrew W. Eckford , Jamie Evans

Many biological and physical systems exhibit population-density dependent transitions to synchronized oscillations in a process often termed "dynamical quorum sensing". Synchronization frequently arises through chemical communication via…

细胞行为 · 定量生物学 2010-12-23 David J. Schwab , Ania Baetica , Pankaj Mehta

A biofilm is a microbial city. It consists of bacteria embedded in an extracellular polymeric substance (EPS) that functions as a protective barrier. Quorum sensing (QS) is a method of bacterial communication, where autoinducers (AIs)…

信号处理 · 电气工程与系统科学 2024-08-15 Yanahan Paramalingam , Hamidreza Arjmandi , Freya Harrison , Tara Schiller , Adam Noel

Bacteria generally live in complicated structures called biofilms, consisting of communicating bacterial colonies and extracellular polymeric substance (EPS). Since biofilms are related to detrimental effects such as infection or antibiotic…

定量方法 · 定量生物学 2023-11-07 Fatih Gulec , Andrew W. Eckford

Molecular Communication (MC) utilizes chemical molecules to transmit information, introducing innovative strategies for pharmaceutical interventions and enhanced immune system monitoring. This paper explores Molecular communication based…

生物大分子 · 定量生物学 2024-12-31 Shees Zulfiqar , Ozgur B. Akan

We explore the critical behaviors in the dynamics of information transfer of a biologically-inspired system by an individual-based model. "Quorum response", a type of social interaction which has been recognized taxonomically in animal…

物理与社会 · 物理学 2013-08-22 Collin Feng Hu
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