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Human brain contains about 10 billion neurons, each of which has about 10~10,000 nerve endings from which neurotransmitters are released in response to incoming spikes, and the released neurotransmitters then bind to receptors located in…

神经元与认知 · 定量生物学 2012-03-06 Xuejuan Zhang , Jianfeng Feng

A central question in neuroscience is to understand how noisy firing patterns are used to transmit information. Because neural spiking is noisy, spiking patterns are often quantified via pairwise correlations, or the probability that two…

神经元与认知 · 定量生物学 2017-05-29 Andrea K. Barreiro , Cheng Ly

Brains learn to represent information from a large set of stimuli, typically by weak supervision. Unsupervised learning is therefore a natural approach for exploring the design of biological neural networks and their computations.…

神经元与认知 · 定量生物学 2025-10-17 Roy Urbach , Elad Schneidman

Different brain areas, such as the cortex and, more specifically, the prefrontal cortex, show great recurrence in their connections, even in early sensory areas. {Several approaches and methods based on trained networks have been proposed…

神经元与认知 · 定量生物学 2022-04-25 Cecilia Jarne

We introduce bio-inspired artificial neural networks consisting of neurons that are additionally characterized by spatial positions. To simulate properties of biological systems we add the costs penalizing long connections and the proximity…

神经与进化计算 · 计算机科学 2019-10-08 Maciej Wołczyk , Jacek Tabor , Marek Śmieja , Szymon Maszke

In this paper, we build a model for biological neural nets where the activity of the network is described by Hawkes processes having a variable length memory. The particularity of this paper is to deal with an infinite number of components.…

概率论 · 数学 2015-09-18 Pierre Hodara , Eva Löcherbach

Motifs are patterns of subgraphs of complex networks. We studied the impact of such patterns of connectivity on the level of correlated, or synchronized, spiking activity among pairs of cells in a recurrent network model of integrate and…

神经元与认知 · 定量生物学 2015-06-05 Yu Hu , James Trousdale , Kresimir Josic , Eric Shea-Brown

Bayesian Networks may be appealing for clinical decision-making due to their inclusion of causal knowledge, but their practical adoption remains limited as a result of their inability to deal with unstructured data. While neural networks do…

机器学习 · 计算机科学 2022-11-16 Paloma Rabaey , Cedric De Boom , Thomas Demeester

In this work we study biological neural networks from an algorithmic perspective, focusing on understanding tradeoffs between computation time and network complexity. Our goal is to abstract real neural networks in a way that, while not…

分布式、并行与集群计算 · 计算机科学 2019-04-30 Nancy Lynch , Cameron Musco , Merav Parter

We present a general class of machine learning algorithms called parametric matrix models. In contrast with most existing machine learning models that imitate the biology of neurons, parametric matrix models use matrix equations that…

机器学习 · 计算机科学 2025-01-07 Patrick Cook , Danny Jammooa , Morten Hjorth-Jensen , Daniel D. Lee , Dean Lee

Next-item prediction is a a popular problem in the recommender systems domain. As the name suggests, the task is to recommend subsequent items that a user would be interested in given contextual information and historical interaction data.…

信息检索 · 计算机科学 2022-05-12 Manoj Reddy Dareddy , Zijun Xue , Nicholas Lin , Junghoo Cho

Neural circuits in the brain perform a variety of essential functions, including input classification, pattern completion, and the generation of rhythms and oscillations that support processes such as breathing and locomotion. There is also…

神经元与认知 · 定量生物学 2024-10-16 Juliana Londono Alvarez

The study of neuronal morphology is important not only for its potential relationship with neuronal dynamics, but also as a means to classify diverse types of cells and compare than among species, organs, and conditions. In the present…

神经元与认知 · 定量生物学 2024-03-11 Alexandre Benatti , Henrique F. de Arruda , Luciano da F. Costa

Modeling uncertainty in deep neural networks, despite recent important advances, is still an open problem. Bayesian neural networks are a powerful solution, where the prior over network weights is a design choice, often a normal…

机器学习 · 统计学 2019-10-29 Raanan Y. Rohekar , Yaniv Gurwicz , Shami Nisimov , Gal Novik

Computational methods for discovering patterns of local correlations in sequences are important in computational biology. Here we show how to determine the optimal partitioning of aligned sequences into non-overlapping segments such that…

计算工程、金融与科学 · 计算机科学 2012-06-26 Joseph Bockhorst , Nebojsa Jojic

In "The Organization of Behavior" (Hebb, 1949), Hebb suggested that the propagation of activity between transiently grouped neurons plays an important role in behavior. Since then, multiple studies have provided evidence supporting Hebb's…

神经元与认知 · 定量生物学 2021-05-28 Ohad Felsenstein , Moshe Abeles

Hypergraphs serve as an effective tool widely adopted to characterize higher-order interactions in complex systems. The most intuitive and commonly used mathematical instrument for representing a hypergraph is the incidence matrix, in which…

社会与信息网络 · 计算机科学 2026-04-22 Junhao Bian , Yilin Bi , Tao Zhou

When a neuron fires and the resulting action potential travels down its axon toward other neurons' dendrites, the effect on each of those neurons is mediated by the weight of the synapse that separates it from the firing neuron. This…

神经元与认知 · 定量生物学 2010-02-19 Andre Nathan , Valmir C. Barbosa

Traditional neural networks assume vectorial inputs as the network is arranged as layers of single line of computing units called neurons. This special structure requires the non-vectorial inputs such as matrices to be converted into…

机器学习 · 计算机科学 2016-12-12 Junbin Gao , Yi Guo , Zhiyong Wang

Attractor dynamics are a fundamental computational motif in neural circuits, supporting diverse cognitive functions through stable, self-sustaining patterns of neural activity. In these lecture notes, we review four key examples that…

神经元与认知 · 定量生物学 2026-01-30 Tala Fakhoury , Elia Turner , Sushrut Thorat , Athena Akrami