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Objective: The efficacy of traditional Chinese medicine (TCM) treatments for Western medicine (WM) diseases relies heavily on the proper classification of patients into TCM syndrome types. We develop a data-driven method for solving the…

机器学习 · 计算机科学 2016-02-25 Nevin L. Zhang , Chen Fu , Teng Fei Liu , Bao Xin Chen , Kin Man Poon , Pei Xian Chen , Yun Ling Zhang

Traditional Chinese Medicine (TCM) is a natural, safe, and effective therapy that has spread and been applied worldwide. The unique TCM diagnosis and treatment system requires a comprehensive analysis of a patient's symptoms hidden in the…

计算与语言 · 计算机科学 2022-08-04 Mucheng Ren , Heyan Huang , Yuxiang Zhou , Qianwen Cao , Yuan Bu , Yang Gao

Natural medicines, particularly Traditional Chinese Medicine (TCM), are gaining global recognition for their therapeutic potential in addressing human symptoms and diseases. TCM, with its systematic theories and extensive practical…

计算与语言 · 计算机科学 2025-05-20 Zhi Liu , Tao Yang , Jing Wang , Yexin Chen , Zhan Gao , Jiaxi Yang , Kui Chen , Bingji Lu , Xiaochen Li , Changyong Luo , Yan Li , Xiaohong Gu , Peng Cao

The surge of large language models (LLMs) has driven significant progress in medical applications, including traditional Chinese medicine (TCM). However, current medical LLMs struggle with TCM diagnosis and syndrome differentiation due to…

Syndrome differentiation in Traditional Chinese Medicine (TCM) is the process of understanding and reasoning body condition, which is the essential step and premise of effective treatments. However, due to its complexity and lack of…

机器学习 · 计算机科学 2019-01-23 Zeyuan Wang , Josiah Poon , Shiding Sun , Simon Poon

Traditional Chinese medicine (TCM) tongue diagnosis, while clinically valuable, faces standardization challenges due to subjective interpretation and inconsistent imaging protocols, compounded by the lack of large-scale, annotated datasets…

图像与视频处理 · 电气工程与系统科学 2025-07-25 Xuebo Jin , Longfei Gao , Anshuo Tong , Zhengyang Chen , Jianlei Kong , Ning Sun , Huijun Ma , Qiang Wang , Yuting Bai , Tingli Su

Alzheimer's disease is a progressive neurodegenerative disorder that primarily affects cognitive functions such as memory, thinking, and behavior. In this disease, there is a critical phase, mild cognitive impairment, that is really…

信号处理 · 电气工程与系统科学 2024-04-02 Arezoo Borji , Taha-Hossein Hejazi , Abbas Seifi

Dietary patterns synthesize multiple related diet components, which can be used by nutrition researchers to examine diet-disease relationships. Latent class models (LCMs) have been used to derive dietary patterns from dietary intake…

统计方法学 · 统计学 2025-04-11 Mengbing Li , Briana Stephenson , Zhenke Wu

Traditional Chinese Medicine (TCM) is a holistic medical system with millennia of accumulated clinical experience, playing a vital role in global healthcare-particularly across East Asia. However, the implicit reasoning, diverse textual…

Long-range temporal coherence (LRTC) is quite common to dynamic systems and is fundamental to the system function. LRTC in the brain has been shown to be important to cognition. Assessing LRTC may provide critical information for…

神经元与认知 · 定量生物学 2024-07-10 Ze Wang

Many diseases display heterogeneity in clinical features and their progression, indicative of the existence of disease subtypes. Extracting patterns of disease variable progression for subtypes has tremendous application in medicine, for…

定量方法 · 定量生物学 2020-08-04 Sanjukta Krishnagopal

Early detection of dementia is crucial to devise effective interventions. Comprehensive cognitive tests, while being the most accurate means of diagnosis, are long and tedious, thus limiting their applicability to a large population,…

计算机视觉与模式识别 · 计算机科学 2025-05-30 Anusha A. S. , Uma Ranjan , Medha Sharma , Siddharth Dutt

Dementia is the fifth cause of death worldwide with 10 million new cases every year. Healthcare applications using machine learning techniques have almost reached the physical limits while more data is becoming available resulting from the…

Magnetic resonance imaging (MRI) is a common technique to scan brains for strokes, tumors, and other abnormalities that cause forms of dementia. However, correctly diagnosing forms of dementia from MRIs is difficult, as nearly 1 in 3…

量子物理 · 物理学 2023-05-16 Ryan Kim

Traditional Chinese Medicine diagnosis and treatment principles, established through centuries of trial-and-error clinical practice, directly maps patient-specific symptom patterns to personalised herbal therapies. These empirical holistic…

We performed a PubMed search to find 148 papers published between January 2010 and December 2019 related to human brain, Diffusion Tensor Imaging (DTI), and Machine Learning (ML). The studies focused on healthy cohorts (n = 15), mental…

机器学习 · 计算机科学 2020-12-22 Ashirbani Saha , Pantea Fadaiefard , Jessica E. Rabski , Alireza Sadeghian , Michael D. Cusimano

Parkinson's disease (PD) is a common neurodegenerative disease with a high degree of heterogeneity in its clinical features, rate of progression, and change of variables over time. In this work, we present a novel data-driven, network-based…

应用统计 · 统计学 2020-07-01 Sanjukta Krishnagopal , Rainer Von Coelln , Lisa M. Shulman , Michelle Girvan

The timely identification of significant memory concern (SMC) is crucial for proactive cognitive health management, especially in an aging population. Detecting SMC early enables timely intervention and personalized care, potentially…

机器学习 · 计算机科学 2024-05-31 M. Sajid , Rahul Sharma , Iman Beheshti , M. Tanveer

Cause-of-death data is fundamental for understanding population health trends and inequalities as well as designing and evaluating public health interventions. A significant proportion of global deaths, particularly in low- and…

应用统计 · 统计学 2025-02-04 Yu Zhu , Zehang Richard Li

Traditional Chinese Medicine (TCM), as an effective alternative medicine, has been receiving increasing attention. In recent years, the rapid development of large language models (LLMs) tailored for TCM has highlighted the urgent need for…

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