相关论文: Inversion of hematocrit partition at microfluidic …
The nature of blood as a suspension of red blood cells makes computational hemodynamics a demanding task. Our coarse-grained blood model, which builds on a lattice Boltzmann method for soft particle suspensions, enables the study of the…
Erythropoiesis is a mechanism for the production of red blood cells by cellular differentiation. It is based on amplification steps due to an interplay between renewal and differentiation in the successive cell compartments from stem cells…
An important step in diagnostics is the isolation of specific cells and microorganisms of interest from blood. Since such bioparticles are often present at very low concentrations, throughput needs to be as high as possible. In addition, to…
Centrifugation is a commonly performed laboratory procedure that helps to separate blood cells such as $RBCs$, $WBCs$, and platelets from plasma or serum. Although centrifugation is a routine procedure in most medical laboratories, the…
In inertial microfluidics lift forces cause a particle to migrate across streamlines to specific positions in the cross section of a microchannel. We control the rotational motion of a particle and demonstrate that this allows to manipulate…
We report the effect of interstitial fluid on the extent of segregation by imaging the pile that results after bidisperse color-coded particles are poured into a silo. Segregation is sharply reduced and preferential clumping of small…
The analysis of the ultrasonic frequency-dependent backscatter coefficient of aggregating red blood cells reveals information about blood structural properties. The difficulty to apply this technique in vivo is due to the…
We perform one and two-parameter numerical bifurcation analysis of a mechanotransduction model approximating the dynamics of mesenchymal stem cell differentiation into neurons, adipocytes, myocytes and osteoblasts. For our analysis, we use…
Modeling of the red blood cell (RBC) shape is an integral part of the experimental and computer simulation investigations of light scattering by these cells for fundamental studies as well as diagnostic applications in techniques like…
Atherosclerosis is a state wherein plaque (fat, cholesterol, and different substances) develops inside the veins that in the end prompts carotid artery stenosis which is a phase of narrowing in the huge courses situated on either side of…
Vascular adhesion of circulating tumor cells (CTCs) is a key step in cancer spreading. If inflammation is recognized to favor the formation of vascular metastatic niches, little is known about the contribution of blood rheology to CTC…
We introduce an in silico model for the initial spread of an aberrant phenotype with Warburg-like overflow metabolism within a healthy homeostatic tissue in contact with a nutrient reservoir (the blood), aimed at characterizing the role of…
The development and time evolution of a transport barrier in a magnetically confined plasma with non-monotonic, nonlinear dependence of the anomalous flux on mean gradients is analyzed. Upon consideration of both the spatial inhomogeneity…
This paper investigates the existence of periodic solutions in blood flow propagating through vessels with free boundary conditions via the bifurcation theory. It is rigorously proved that a local $C^1$-curve of small-amplitude periodic…
Controlling flow-induced segregation in a granular mixture is highly relevant to many industrial settings. To enhance mixing or promote segregation, the continuous gravity flow of a bidisperse granular mixture through a series of narrow…
Understanding anomalous transport and reaction kinetics due to microscopic physical and chemical disorder is a long-standing goal in many fields including geophysics, biology, and engineering. We consider reaction-diffusion characterized by…
The structure-function relationship is at the heart of biology and major protein deformations are correlated to specific functions. In the case of heme proteins, doming is associated with the respiratory function in hemoglobin and…
We use plate drag to study the response of granular media to localized forcing as a function of volume fraction, $\phi$. A bifurcation in the force and flow occurs at the onset of dilatancy, $\phi_c.$ Below $\phi_c$ rapid fluctuations in…
In a half-filled rotating drum, the size segregation of particles of equal density builds a ring pattern of the large particles, whose location continuously varies from the periphery to the center depending on the size ratio between…
A classical microscopic theory of rovibrational motion at high angular momenta in symmetrical non-linear molecules AB$_2$ is derived within the framework of small oscillations near the stationary states of a rotating molecule. The…