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Scalable production of all-electronic DNA biosensors with high sensitivity and selectivity is a critical enabling step for research and applications associated with detection of DNA hybridization. We have developed a scalable and very…

应用物理 · 物理学 2017-08-31 Jinglei Ping , Ramya Vishnubhotla , Amey Vrudhula , A. T. Charlie Johnson

We present a method where a bioactive functional layer on an electrically conductive thin film with high sheet resistance can be effectively used for complementary electrochemical impedance spectroscopy biosensing. The functional layer's…

材料科学 · 物理学 2025-04-04 Munis Khan , Ivan Mijakovic , Santosh Pandit , August Yurgens

This paper presents an electrolytically gated broadband microwave sensor where atomically-thin graphene layers are integrated into coplanar waveguides and coupled with microfluidic channels. The interaction between a solution under test and…

Field-Effect Transistors with graphene channels or GFETs are an interesting alternative for the detection of analytes in biological fluids since the electrical behavior of the channel changes when exposed to a sample (among other detection…

医学物理 · 物理学 2024-07-16 Ricardo Bravo , Ricardo Silva , Eric Barret , John Brunnings , Adianette Segarra

We describe a simple and scalable method for the transfer of CVD graphene for the fabrication of field effect transistors. This is a dry process that uses a modified RCA cleaning step to improve the surface quality. In contrast to…

介观与纳米尺度物理 · 物理学 2016-01-07 T. S. Abhilash , Roberto De Alba , Nikolay Zhelev , Harold G Craighead , Jeevak M Parpia

Current situation of COVID-19 demands a rapid, reliable, cost-effective, facile detection strategy to break the transmission chain and biosensor has emerged as a feasible solution for this purpose. Introduction of nanomaterials has…

应用物理 · 物理学 2020-12-11 Joydip Sengupta , Chaudhery Mustansar Hussain

Electrical detection of messenger ribonucleic acid (mRNA) is a promising approach to enhancing transcriptomics and disease diagnostics because of its sensitivity, rapidity, and modularity. Reported here is a fast SARS-CoV-2 mRNA biosensor…

生物大分子 · 定量生物学 2022-05-12 Nicholas E. Fuhr , Mohamed Azize , David J. Bishop

This review provides a critical overview of current developments on nanoelectronic biochemical sensors based on graphene. Composed of a single layer of conjugated carbon atoms, graphene has outstanding high carrier mobility and low…

We report on the integration of large area CVD grown single- and bilayer graphene transparent conductive electrodes (TCEs) on amorphous silicon multispectral photodetectors. The broadband transmission of graphene results in 440% enhancement…

应用物理 · 物理学 2017-08-15 Daniel S. Schneider , Andreas Bablich , Max C. Lemme

This work presents an innovative magnetoelastic (ME) biosensor using graphene functionalized with the SARS-CoV-2 N protein for antibody detection via magnetoelastic resonance. Graphene was chosen for its biocompatibility and high surface…

Identification of non-amplified DNA sequences and single-base mutations is essential for molecular biology and genetic diagnostics. This paper reports a novel sensor consisting of electrochemically-gated graphene coplanar waveguides coupled…

Longitudinal resolution and lateral sensitivity are decisive characteristics that determine the suitability of a nanopore sensor for sequencing a strand of DNA as well as other important polymers. Previous modeling of DNA induced ionic…

生物物理 · 物理学 2012-05-18 Slaven Garaj , Song Liu , Daniel Branton , Jene A. Golovchenko

Dynamic wavelength tunability has long been the holy grail of photodetector technology. Because of its atomic thickness and unique properties, graphene opens up new paradigms to realize this concept, but so far this has been elusive…

介观与纳米尺度物理 · 物理学 2017-03-08 François Léonard , Catalin D. Spataru , Michael Goldflam , David W. Peters , Thomas E. Beechem

Graphene field effect transistors (G-FETs) have appeared as suitable candidates for sensing charges and have thus attracted large interest for ion and chemical detections. In particular, their high sensitivity, chemical robustness,…

介观与纳米尺度物理 · 物理学 2024-02-08 Océane Terral , Guillaume Audic , Arnaud Claudel , Justine Magnat , Aurélie Dupont , Christophe J. Moreau , Cécile Delacour

The success of graphene for nanopore DNA sequencing has shown that it is possible to explore other potential single-atom and few-atom thick layers of elemental 2D materials beyond graphene (e.g., phosphorene and silicene). Using density…

介观与纳米尺度物理 · 物理学 2021-12-15 Matthew B. Henry , Mukesh Tumbapo , Benjamin O. Tayo

Graphene Field-Effect Transistors (GFETs) are increasingly employed as biochemical sensors due to their exceptional electronic properties, surface sensitivity, and potential for miniaturization. A critical challenge in deploying GFETs is…

Graphene is a true two dimensional material with exceptional electronic properties and enormous potential for practical applications. Graphene's promise as a chemical sensor material has been noted but there has been relatively little work…

介观与纳米尺度物理 · 物理学 2015-05-19 Ye Lu , Brett R. Goldsmith , Nicholas J. Kybert , A. T. Charlie Johnson

Translocation of DNA through a nanopore with embedded electrodes is at the centre of new rapid inexpensive sequencing methods which allow distinguishing the four nucleobases by their different electronic structure. However, the subnanometer…

介观与纳米尺度物理 · 物理学 2012-06-20 Yuhui He , Makusu Tsutsui , Ralph H. Scheicher , Masateru Taniguchi , Tomoji Kawai

Recent progress in the synthesis of highly stable, eco-friendly, cost-effective transition metal-dichalcogenides (TMDC) quantum dots (QDs) with their broadband absorption spectrum and wavelength selectivity features have led to their…

Polarization characteristic of ultrafast carrier dynamics in multi-layer CVD-grown graphene is probed with tilted beams (with respected to the graphene plane). The graphene ultrafast carrier dynamics measurement greatly depends on both…

介观与纳米尺度物理 · 物理学 2013-03-01 Xiao-Qing Yan , Zhi-Bo Liu , Jun Yao , Xin Zhao , Xu-Dong Chen , Xiang-Tian Kong , Fei Xing , Yongsheng Chen , Jian-Guo Tian
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