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The analysis of randomized trials is often complicated by the occurrence of intercurrent events and missing values. Even though there are different strategies to address missing values it is still common to require missing values…

统计方法学 · 统计学 2025-11-11 A. Ruiz de Villa , Ll. Badiella

We study high-dimensional regression with missing entries in the covariates. A common strategy in practice is to \emph{impute} the missing entries with an appropriate substitute and then implement a standard statistical procedure acting as…

统计理论 · 数学 2020-01-28 Kabir Aladin Chandrasekher , Ahmed El Alaoui , Andrea Montanari

The analysis of incomplete contingency tables is a practical and an interesting problem. In this paper, we provide characterizations for the various missing mechanisms of a variable in terms of response and non-response odds for two and…

统计方法学 · 统计学 2018-11-27 S. Ghosh , P. Vellaisamy

The primary analysis of clinical trials in diabetes therapeutic area often involves a mixed-model repeated measure (MMRM) approach to estimate the average treatment effect for longitudinal continuous outcome, and a generalized linear mixed…

应用统计 · 统计学 2022-08-03 Lingjing Jiang , Michael Rosenblum , Yu Du

We propose a general semi-supervised inference framework focused on the estimation of the population mean. As usual in semi-supervised settings, there exists an unlabeled sample of covariate vectors and a labeled sample consisting of…

统计方法学 · 统计学 2018-08-15 Anru Zhang , Lawrence D. Brown , T. Tony Cai

Randomization inference is a widely-used and appealing approach for analyzing treatment effects in randomized experiments, as it is finite-sample valid and does not require any distributional assumptions. However, naive application of…

计量经济学 · 经济学 2026-05-12 Xinran Li , Peizan Sheng , Zeyang Yu

The maximum likelihood estimator (MLE) is pivotal in statistical inference, yet its application is often hindered by the absence of closed-form solutions for many models. This poses challenges in real-time computation scenarios,…

统计方法学 · 统计学 2025-04-16 Pedro L. Ramos , Eduardo Ramos , Francisco A. Rodrigues , Francisco Louzada

We address the practical construction of asymptotic confidence intervals for smooth (i.e., path-wise differentiable), real-valued statistical parameters by targeted learning from independent and identically distributed data in contexts…

统计理论 · 数学 2016-07-01 Patrice Bertail , Antoine Chambaz , Emilien Joly

Identifying a biomarker or treatment-dose threshold that marks a specified level of risk is an important problem, especially in clinical trials. This risk, viewed as a function of thresholds and possibly adjusted for covariates, we call the…

统计方法学 · 统计学 2023-03-22 Lars van der Laan , Wenbo Zhang , Peter B. Gilbert

We consider computationally-efficient estimation of population parameters when observations are subject to missing data. In particular, we consider estimation under the realizable contamination model of missing data in which an $\epsilon$…

统计理论 · 数学 2026-03-18 Kabir Aladin Verchand , Ankit Pensia , Saminul Haque , Rohith Kuditipudi

In Ruckdeschel[10], we derive an asymptotic expansion of the maximal mean squared error (MSE) of location M-estimators on suitably thinned out, shrinking gross error neighborhoods. In this paper, we compile several consequences of this…

统计理论 · 数学 2010-06-02 Peter Ruckdeschel

The estimation of missing input vector elements in real time processing applications requires a system that possesses the knowledge of certain characteristics such as correlations between variables, which are inherent in the input space.…

应用统计 · 统计学 2007-05-23 Fulufhelo V. Nelwamondo , Shakir Mohamed , Tshilidzi Marwala

We consider the problem of estimating a dose-response curve. Continuous treatments arise often in practice, e.g. in the form of time spent on an operation, distance traveled to a location or dosage of a drug. Letting $A$ denote a continuous…

统计方法学 · 统计学 2026-04-14 Matteo Bonvini , Edward H. Kennedy

We introduce a novel approach to estimation problems in settings with missing data. Our proposal -- the Correlation-Assisted Missing data (CAM) estimator -- works by exploiting the relationship between the observations with missing features…

统计方法学 · 统计学 2020-03-02 Timothy I. Cannings , Yingying Fan

Modern large-scale statistical models require to estimate thousands to millions of parameters. This is often accomplished by iterative algorithms such as gradient descent, projected gradient descent or their accelerated versions. What are…

机器学习 · 统计学 2020-03-04 Michael Celentano , Andrea Montanari , Yuchen Wu

We solve the problem of estimating the distribution of presumed i.i.d. observations for the total variation loss. Our approach is based on density models and is versatile enough to cope with many different ones, including some density…

统计理论 · 数学 2024-01-05 Y. Baraud , H. Halconruy , G. Maillard

We consider the problem of estimating the joint distribution of $n$ independent random variables. Our approach is based on a family of candidate probabilities that we shall call a model and which is chosen to either contain the true…

统计理论 · 数学 2021-06-01 Yannick Baraud

We study a fundamental class of regression models called the second order linear model (SLM). The SLM extends the linear model to high order functional space and has attracted considerable research interest recently. Yet how to efficiently…

机器学习 · 统计学 2017-06-26 Ming Lin , Shuang Qiu , Bin Hong , Jieping Ye

Observational studies are the primary source of data for causal inference, but it is challenging when existing unmeasured confounding. Missing data problems are also common in observational studies. How to obtain the causal effects from the…

统计方法学 · 统计学 2023-05-15 Renzhong Zheng

Covariate adjustment can improve precision in analyzing randomized experiments. With fully observed data, regression adjustment and propensity score weighting are asymptotically equivalent in improving efficiency over unadjusted analysis.…

统计方法学 · 统计学 2024-03-06 Anqi Zhao , Peng Ding , Fan Li