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相关论文: Learning Linguistic Biomarkers for Predicting Mild…

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In this study we developed an automated system that evaluates speech and language features from audio recordings of neuropsychological examinations of 92 subjects in the Framingham Heart Study. A total of 265 features were used in an…

人工智能 · 计算机科学 2017-10-23 Tuka Alhanai , Rhoda Au , James Glass

The global prevalence of dementia is projected to double by 2050, highlighting the urgent need for scalable diagnostic tools. This study utilizes digital cognitive tasks with eye-tracking data correlated with memory processes to distinguish…

人机交互 · 计算机科学 2025-08-28 Tomás Silva Santos Rocha , Anastasiia Mikhailova , Moreno I. Coco , José Santos-Victor

This study explores a multi-lingual audio self-supervised learning model for detecting mild cognitive impairment (MCI) using the TAUKADIAL cross-lingual dataset. While speech transcription-based detection with BERT models is effective,…

音频与语音处理 · 电气工程与系统科学 2025-01-28 Yueguan Wang , Tatsunari Matsushima , Soichiro Matsushima , Toshimitsu Sakai

Early diagnosis of dementia, particularly in the prodromal stage (i.e., mild cognitive impairment, or MCI), has become a research and clinical priority but remains challenging. Automated analysis of the drawing process has been studied as a…

信号处理 · 电气工程与系统科学 2022-11-17 Yasunori Yamada , Masatomo Kobayashi , Kaoru Shinkawa , Miyuki Nemoto , Miho Ota , Kiyotaka Nemoto , Tetsuaki Arai

Deep learning (DL) has been used in the automatic diagnosis of Mild Cognitive Impairment (MCI) and Alzheimer's Disease (AD) with brain imaging data. However, previous methods have not fully exploited the relation between brain image and…

计算机视觉与模式识别 · 计算机科学 2023-10-24 Luoyao Kang , Haifan Gong , Xiang Wan , Haofeng Li

Early detection of dementia is crucial to devise effective interventions. Comprehensive cognitive tests, while being the most accurate means of diagnosis, are long and tedious, thus limiting their applicability to a large population,…

计算机视觉与模式识别 · 计算机科学 2025-05-30 Anusha A. S. , Uma Ranjan , Medha Sharma , Siddharth Dutt

Alzheimer's disease (AD) and its prodromal stage, Mild Cognitive Impairment (MCI), are associated with subtle declines in memory, attention, and language that often go undetected until late in progression. Traditional diagnostic tools such…

人机交互 · 计算机科学 2025-12-30 Ananya Drishti , Mahfuza Farooque

Alzheimer's disease is the most common cause of dementia that affects millions of lives worldwide. Investigating the underlying causes and risk factors of Alzheimer's disease is essential to prevent its progression. Mild Cognitive…

机器学习 · 计算机科学 2023-08-22 Deniz Sezin Ayvaz , Inci M. Baytas

Mild cognitive impairment(MCI) is a precursor of Alzheimer's disease(AD), and the detection of MCI is of great clinical significance. Analyzing the structural brain networks of patients is vital for the recognition of MCI. However, the…

神经元与认知 · 定量生物学 2022-08-19 Heng Kong , Shuqiang Wang

We evaluate cognitive impairment (CI) classification from transcripts of speech in English, Slovene, and Korean. We compare zero-shot large language models (LLMs) used as direct classifiers under three input settings -- transcript-only,…

INTRODUCTION: Mild cognitive impairment (MCI) is characterized by a decline in cognitive functions beyond typical age and education-related expectations. Since, MCI has been linked to reduced social interactions and increased aimless…

人工智能 · 计算机科学 2024-08-21 Chaitra Hegde , Yashar Kiarashi , Allan I Levey , Amy D Rodriguez , Hyeokhyen Kwon , Gari D Clifford

The paper proposes a novel approach of survival transformers and extreme gradient boosting models in predicting cognitive deterioration in individuals with mild cognitive impairment (MCI) using metabolomics data in the ADNI cohort. By…

机器学习 · 计算机科学 2024-09-25 Henry Musto , Daniel Stamate , Doina Logofatu , Daniel Stahl

Mild cognitive impairment (MCI) is a major public health concern due to its high risk of progressing to dementia. This study investigates the potential of detecting MCI with spontaneous voice assistant (VA) commands from 35 older adults in…

音频与语音处理 · 电气工程与系统科学 2024-11-08 Nana Lin , Youxiang Zhu , Xiaohui Liang , John A. Batsis , Caroline Summerour

Alzheimer's disease (AD) is the most common age-related dementia. Mild cognitive impairment (MCI) is the early stage of cognitive decline before AD. It is crucial to predict the MCI-to-AD conversion for precise management, which remains…

图像与视频处理 · 电气工程与系统科学 2022-03-10 Yiran Wei , Stephen J. Price , Carola-Bibiane Schönlieb , Chao Li

The prediction of subjects with mild cognitive impairment (MCI) who will progress to Alzheimer's disease (AD) is clinically relevant, and may above all have a significant impact on accelerate the development of new treatments. In this…

图像与视频处理 · 电气工程与系统科学 2019-07-16 Kilian Hett , Vinh-Thong Ta , José V. Manjón , Pierrick Coupé

Dementia is a progressive cognitive syndrome with Alzheimer's disease (AD) as the leading cause. Conversation-based AD detection offers a cost-effective alternative to clinical methods, as language dysfunction is an early biomarker of AD.…

计算与语言 · 计算机科学 2025-02-27 Arezo Shakeri , Mina Farmanbar , Krisztian Balog

The transition from mild cognitive impairment (MCI) to Alzheimer's disease (AD) is of great interest to clinical researchers. This phenomenon also serves as a valuable data source for quantitative methodological researchers developing new…

应用统计 · 统计学 2020-12-02 Zihuan Liu , Tapabrate Maiti , Andrew R. Bender

Mild Cognitive Impairment (MCI) affects 12-18% of individuals over 60. MCI patients exhibit cognitive dysfunctions without significant daily functional loss. While MCI may progress to dementia, predicting this transition remains a clinical…

Speech, language, and communication deficits are present in most neurodegenerative syndromes. They enable the early detection, diagnosis, treatment planning, and monitoring of neurocognitive disease progression as part of traditional…

计算与语言 · 计算机科学 2023-12-07 Charalambos Themistocleous , Kyrana Tsapkini , Dimitrios Kokkinakis

We extend the SKIP-GRAM model of Mikolov et al. (2013a) by taking visual information into account. Like SKIP-GRAM, our multimodal models (MMSKIP-GRAM) build vector-based word representations by learning to predict linguistic contexts in…

计算与语言 · 计算机科学 2015-03-13 Angeliki Lazaridou , Nghia The Pham , Marco Baroni