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We apply an information theoretic treatment of action potential time series measured with microelectrode arrays to estimate the connectivity of mammalian neuronal cell assemblies grown {\it in vitro}. We infer connectivity between two…

神经元与认知 · 定量生物学 2007-05-23 Luis M. A. Bettencourt , Greg J. Stephens , Michael I. Ham , Guenter W. Gross

Human brains lie at the core of complex neurobiological systems, where the neurons, circuits, and subsystems interact in enigmatic ways. Understanding the structural and functional mechanisms of the brain has long been an intriguing pursuit…

神经元与认知 · 定量生物学 2022-07-26 Hejie Cui , Wei Dai , Yanqiao Zhu , Xiaoxiao Li , Lifang He , Carl Yang

This article presents a review of computational methods for connectivity inference from neural activity data derived from multi-electrode recordings or fluorescence imaging. We first identify biophysical and technical challenges in…

神经元与认知 · 定量生物学 2017-12-18 Ildefons Magrans de Abril , Junichiro Yoshimoto , Kenji Doya

Lattice field theories are fundamental testbeds for computational physics; yet, sampling their Boltzmann distributions remains challenging due to multimodality and long-range correlations. While normalizing flows offer a promising…

机器学习 · 计算机科学 2025-10-16 Andrey Bryutkin , Youssef Marzouk

Resting-state functional MRI (rs-fMRI) is widely used to noninvasively study human brain networks. Network functional connectivity is often estimated by calculating the timeseries correlation between blood-oxygen-level dependent (BOLD)…

定量方法 · 定量生物学 2017-01-25 Nan Xu , R. Nathan Spreng , Peter C. Doerschuk

Correlations in the signal observed via functional Magnetic Resonance Imaging (fMRI), are expected to reveal the interactions in the underlying neural populations through hemodynamic response. In particular, they highlight distributed set…

应用统计 · 统计学 2012-02-07 Gaël Varoquaux , Alexandre Gramfort , Jean Baptiste Poline , Bertrand Thirion

Graph connectivity is a fundamental combinatorial optimization problem that arises in many practical applications, where usually a spanning subgraph of a network is used for its operation. However, in the real world, links may fail…

数据结构与算法 · 计算机科学 2022-09-13 Dimitris Fotakis , Evangelia Gergatsouli , Charilaos Pipis , Miltiadis Stouras , Christos Tzamos

Understanding the dynamic reorganization of brain networks is critical for predicting cognitive decline, neurological progression, and individual variability in clinical outcomes. This work proposes a multimodal graph neural network…

机器学习 · 计算机科学 2026-02-11 Preksha Girish , Rachana Mysore , Kiran K. N. , Hiranmayee R. , Shipra Prashanth , Shrey Kumar

One of the central challenges facing modern neuroscience is to explain the ability of the nervous system to coherently integrate information across distinct functional modules in the absence of a central executive. To this end Tononi et al.…

神经元与认知 · 定量生物学 2010-11-30 L. Barnett , C. L. Buckley , S. Bullock

The brain is a highly complex system. Most of such complexity stems from the intermingled connections between its parts, which give rise to rich dynamics and to the emergence of high-level cognitive functions. Disentangling the underlying…

神经元与认知 · 定量生物学 2023-08-14 Vito Dichio , Fabrizio De Vico Fallani

The exploration of Graph Neural Networks (GNNs) for processing graph-structured data has expanded, particularly their potential for causal analysis due to their universal approximation capabilities. Anticipated to significantly enhance…

机器学习 · 计算机科学 2024-01-30 Simi Job , Xiaohui Tao , Taotao Cai , Lin Li , Haoran Xie , Jianming Yong

The relationship between brain structure and function has been probed using a variety of approaches, but how the underlying structural connectivity of the human brain drives behavior is far from understood. To investigate the effect of…

神经元与认知 · 定量生物学 2018-11-15 Kanika Bansal , John D. Medaglia , Danielle S. Bassett , Jean M. Vettel , Sarah F. Muldoon

We present an algorithm to identify sparse dependence structure in continuous and non-Gaussian probability distributions, given a corresponding set of data. The conditional independence structure of an arbitrary distribution can be…

机器学习 · 计算机科学 2017-11-07 Rebecca E. Morrison , Ricardo Baptista , Youssef Marzouk

Recent studies proposed the use of Total Correlation to describe functional connectivity among brain regions as a multivariate alternative to conventional pair-wise measures such as correlation or mutual information. In this work we build…

神经元与认知 · 定量生物学 2022-11-28 Qiang Li , Greg Ver Steeg , Shujian Yu , Jesus Malo

While correlation measures are used to discern statistical relationships between observed variables in almost all branches of data-driven scientific inquiry, what we are really interested in is the existence of causal dependence. Designing…

机器学习 · 计算机科学 2014-06-26 Ishanu Chattopadhyay

Neural networks are often represented as graphs of connections between neurons. However, despite their wide use, there is currently little understanding of the relationship between the graph structure of the neural network and its…

机器学习 · 计算机科学 2020-08-28 Jiaxuan You , Jure Leskovec , Kaiming He , Saining Xie

With the advancements in graph neural network, there has been increasing interest in applying this network to ECG signal analysis. In this study, we generated an adjacency matrix using correlation matrix of extracted features and applied a…

信号处理 · 电气工程与系统科学 2025-02-11 Seungwoo Han

This article focuses on the problem of studying shared- and individual-specific structure in replicated networks or graph-valued data. In particular, the observed data consist of $n$ graphs, $G_i, i=1,\ldots,n$, with each graph consisting…

统计计算 · 统计学 2018-04-13 Lu Wang , Zhengwu Zhang , David Dunson

Graph theory is a promising approach in handling the problem of estimating the connectivity probability of vehicular ad-hoc networks (VANETs). With a communication network represented as graph, graph connectivity indicators become valid for…

网络与互联网体系结构 · 计算机科学 2023-05-03 Samar Elaraby , Sherif M. Abuelenin

Neural systems are networks, and strategic comparisons between multiple networks are a prevalent task in many research scenarios. In this study, we construct a statistical test for the comparison of matrices representing pairwise aspects of…

神经元与认知 · 定量生物学 2023-02-08 Robin Gutzen , Sonja Grün , Michael Denker