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Medical decision-making makes frequent use of algorithms that combine risk equations with rules, providing clear and standardized treatment pathways. Symbolic regression (SR) traditionally limits its search space to continuous function…

Decision trees are powerful machine learning algorithms, widely used in fields such as economics and medicine for their simplicity and interpretability. However, decision trees such as CART are prone to overfitting, especially when grown…

机器学习 · 统计学 2026-01-13 Likun Zhang , Wei Ma

Regression trees are a popular machine learning algorithm that fit piecewise constant models by recursively partitioning the predictor space. This paper focuses on statistical inference for a data-dependent model obtained from a fitted…

统计方法学 · 统计学 2025-12-17 Soham Bakshi , Yiling Huang , Snigdha Panigrahi , Walter Dempsey

An individualized treatment rule (ITR) tailors treatments to a patient's specific characteristics. However, randomized controlled trials (RCTs) are often underpowered to detect the treatment effect heterogeneity needed for reliable ITR…

统计方法学 · 统计学 2026-04-14 Yuan Bian , Donglin Zeng , Hyun-Joon Yang , Leanne M. Williams , Yuanjia Wang

In many healthcare settings, intuitive decision rules for risk stratification can help effective hospital resource allocation. This paper introduces a novel variant of decision tree algorithms that produces a chain of decisions, not a…

机器学习 · 统计学 2016-06-17 Yubin Park , Joyce Ho , Joydeep Ghosh

Trustworthy Artificial Intelligence solutions are essential in today's data-driven applications, prioritizing principles such as robustness, safety, transparency, explainability, and privacy among others. This has led to the emergence of…

机器学习 · 计算机科学 2024-04-04 Alberto Argente-Garrido , Cristina Zuheros , M. Victoria Luzón , Francisco Herrera

In the fight against hard-to-treat diseases such as cancer, it is often difficult to discover new treatments that benefit all subjects. For regulatory agency approval, it is more practical to identify subgroups of subjects for whom the…

统计方法学 · 统计学 2014-10-09 Wei-Yin Loh , Xu He , Michael Man

A promising application of AI to healthcare is the retrieval of information from electronic health records (EHRs), e.g. to aid clinicians in finding relevant information for a consultation or to recruit suitable patients for a study. This…

计算与语言 · 计算机科学 2020-11-02 Claudia Schulz , Josh Levy-Kramer , Camille Van Assel , Miklos Kepes , Nils Hammerla

Integrative analysis of multiple datasets for estimating optimal individualized treatment rules (ITRs) can enhance decision efficiency. A central challenge is posterior shift, wherein the conditional distribution of potential outcomes given…

机器学习 · 统计学 2026-03-09 Wenhai Cui , Wen Su , Xingqiu Zhao

Electronic health records (EHR's) are only a first step in capturing and utilizing health-related data - the problem is turning that data into useful information. Models produced via data mining and predictive analysis profile inherited…

数据库 · 计算机科学 2011-12-08 Casey Bennett , Thomas Doub

While artificial intelligence (AI)-based decision-making systems are increasingly popular, significant concerns on the potential discrimination during the AI decision-making process have been observed. For example, the distribution of…

机器学习 · 计算机科学 2025-08-05 Wenbin Zhang

Decision trees have been a very popular class of predictive models for decades due to their interpretability and good performance on categorical features. However, they are not always robust and tend to overfit the data. Additionally, if…

机器学习 · 计算机科学 2019-08-14 Oktay Gunluk , Jayant Kalagnanam , Minhan Li , Matt Menickelly , Katya Scheinberg

Most datasets suffer from partial or complete missing values, which has downstream limitations on the available models on which to test the data and on any statistical inferences that can be made from the data. Several imputation techniques…

机器学习 · 统计学 2023-02-09 Adrienne Kline , Yuan Luo

In recent years, stream data have become an immensely growing area of research for the database, computer science and data mining communities. Stream data is an ordered sequence of instances. In many applications of data stream mining data…

数据库 · 计算机科学 2014-02-10 Nishant Vadnere , R. G. Mehta , D. P. Rana , N. J. Mistry , M. M. Raghuwanshi

The main focus of image mining in the proposed method is concerned with the classification of brain tumor in the CT scan brain images. The major steps involved in the system are: pre-processing, feature extraction, association rule mining…

计算机视觉与模式识别 · 计算机科学 2010-03-25 P. Rajendran , M. Madheswaran

Precision medicine involves developing individualized treatment regimes (ITRs) which allow for treatment decisions to be tailored to patient characteristics. Naturally, the identification of the optimal regime, that is, the rule which…

统计方法学 · 统计学 2025-09-30 Misha Dolmatov , Erica E. M. Moodie , David A. Stephens , Dipankar Bandyopadhyay

Artificial Intelligence (AI) has already made a huge impact on our current technological trends. Through AI developments, machines are now given power and intelligence to behave and work like human mind. In this research project, we propose…

计算机与社会 · 计算机科学 2018-08-07 Rida Sara Khan , Asad Ali Zardar , Zeeshan Bhatti

When treatments are non-randomly assigned, continuous, and yield heterogeneous effects at the same intensity, causal identification becomes particularly challenging. In such contexts, existing approaches often fail to provide…

计量经济学 · 经济学 2026-03-05 Augusto Cerqua , Roberta Di Stefano , Raffaele Mattera

This paper proposes FREEtree, a tree-based method for high dimensional longitudinal data with correlated features. Popular machine learning approaches, like Random Forests, commonly used for variable selection do not perform well when there…

Algorithms and technologies are essential tools that pervade all aspects of our daily lives. In the last decades, health care research benefited from new computer-based recruiting methods, the use of federated architectures for data…

计算机与社会 · 计算机科学 2023-01-26 Chiara Criscuolo , Tommaso Dolci , Mattia Salnitri