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相关论文: HEp-2 Cell Classification: The Role of Gaussian Sc…

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The Anti-Nuclear Antibody (ANA) clinical pathology test is commonly used to identify the existence of various diseases. A hallmark method for identifying the presence of ANAs is the Indirect Immunofluorescence method on Human Epithelial…

细胞行为 · 定量生物学 2013-04-05 Arnold Wiliem , Yongkang Wong , Conrad Sanderson , Peter Hobson , Shaokang Chen , Brian C. Lovell

Efficient Human Epithelial-2 (HEp-2) cell image classification can facilitate the diagnosis of many autoimmune diseases. This paper presents an automatic framework for this classification task, by utilizing the deep convolutional neural…

计算机视觉与模式识别 · 计算机科学 2015-05-19 Zhimin Gao , Lei Wang , Luping Zhou , Jianjia Zhang

Indirect Immunofluorescence (IIF) HEp-2 cell image is an effective evidence for diagnosis of autoimmune diseases. Recently computer-aided diagnosis of autoimmune diseases by IIF HEp-2 cell classification has attracted great attention.…

计算机视觉与模式识别 · 计算机科学 2015-02-17 Xianbiao Qi , Guoying Zhao , Chun-Guang Li , Jun Guo , Matti Pietikäinen

This paper describes a novel system for automatic classification of images obtained from Anti-Nuclear Antibody (ANA) pathology tests on Human Epithelial type 2 (HEp-2) cells using the Indirect Immunofluorescence (IIF) protocol. The IIF…

细胞行为 · 定量生物学 2014-04-15 Arnold Wiliem , Conrad Sanderson , Yongkang Wong , Peter Hobson , Rodney F. Minchin , Brian C. Lovell

Recently, there has been a growing interest in developing Computer Aided Diagnostic (CAD) systems for improving the reliability and consistency of pathology test results. This paper describes a novel CAD system for the Anti-Nuclear Antibody…

计算机视觉与模式识别 · 计算机科学 2016-11-15 Arnold Wiliem , Peter Hobson , Brian C. Lovell

Classification of HEp-2 cell patterns plays a significant role in the indirect immunofluorescence test for identifying autoimmune diseases in the human body. Many automatic HEp-2 cell classification methods have been proposed in recent…

计算机视觉与模式识别 · 计算机科学 2020-08-07 Saimunur Rahman , Lei Wang , Changming Sun , Luping Zhou

Automatic classification of Human Epithelial Type-2 (HEp-2) cells staining patterns is an important and yet a challenging problem. Although both shallow and deep methods have been applied, the study of deep convolutional networks (CNNs) on…

计算机视觉与模式识别 · 计算机科学 2018-02-15 Hongwei Li , Wei-Shi Zheng , Jianguo Zhang

The overexpression of human epidermal growth factor receptor 2 (HER2) has been established as a therapeutic target in multiple types of cancers, such as breast and gastric cancers. Immunohistochemistry (IHC) is employed as a basic HER2 test…

图像与视频处理 · 电气工程与系统科学 2020-09-16 Jun Zhang , Kuan Tian , Pei Dong , Haocheng Shen , Kezhou Yan , Jianhua Yao , Junzhou Huang , Xiao Han

The antinuclear antibody detection with human epithelial cells is a popular approach for autoimmune diseases diagnosis. The manual evaluation demands time, effort and capital, and automation in screening can greatly aid the physicians in…

计算机视觉与模式识别 · 计算机科学 2018-10-31 Vibha Gupta , Arnav Bhavsar

Evaluating expression of the Human epidermal growth factor receptor 2 (Her2) by visual examination of immunohistochemistry (IHC) on invasive breast cancer (BCa) is a key part of the diagnostic assessment of BCa due to its recognised…

Human epidermal growth factor receptor 2 (HER2) is a critical protein in cancer cell growth that signifies the aggressiveness of breast cancer (BC) and helps predict its prognosis. Accurate assessment of immunohistochemically (IHC) stained…

The popular use of histopathology images, such as hematoxylin and eosin (H&E), has proven to be useful in detecting tumors. However, moving such cancer cases forward for treatment requires accurate on the amount of the human epidermal…

计算机视觉与模式识别 · 计算机科学 2025-12-30 Olaide N. Oyelade , Oliver Hoxey , Yulia Humrye

In this article, we propose a novel spatial global-local spike-and-slab selection prior for image-on-scalar regression. We consider a Bayesian hierarchical Gaussian process model for image smoothing, that uses a flexible Inverse-Wishart…

统计方法学 · 统计学 2022-12-19 Zijian Zeng , Meng Li , Marina Vannucci

Expression of human epidermal growth factor receptor 2 (HER2) is an important biomarker in breast cancer patients who can benefit from cost-effective automatic Hematoxylin and Eosin (H\&E) HER2 scoring. However, developing such scoring…

计算机视觉与模式识别 · 计算机科学 2024-11-11 Rawan S. Abdulsadig , Bryan M. Williams , Nikolay Burlutskiy

In the diagnosis of autoimmune diseases, an important task is to classify images of slides containing several HEp-2 cells. All cells from one slide share the same label, and by classifying cells from one slide independently, some…

计算机视觉与模式识别 · 计算机科学 2014-02-07 David M. J. Tax , Veronika Cheplygina , Marco Loog

Histopathological images are widely used for the analysis of diseased (tumor) tissues and patient treatment selection. While the majority of microscopy image processing was previously done manually by pathologists, recent advances in…

图像与视频处理 · 电气工程与系统科学 2024-07-12 Andrey Ignatov , Josephine Yates , Valentina Boeva

The rapid development of digital pathology and modern deep learning has facilitated the emergence of pathology foundation models that are expected to solve general pathology problems under various disease conditions in one unified model,…

计算机视觉与模式识别 · 计算机科学 2025-07-10 Yutong Sun , Sichen Zhu , Peng Qiu

Histology imaging is an important tool in medical diagnosis and research, enabling the examination of tissue structure and composition at the microscopic level. Understanding the underlying molecular mechanisms of tissue architecture is…

计算机视觉与模式识别 · 计算机科学 2023-10-30 Ronald Xie , Kuan Pang , Sai W. Chung , Catia T. Perciani , Sonya A. MacParland , Bo Wang , Gary D. Bader

The overexpression of the human epidermal growth factor receptor 2 (HER2) in breast cells is a key driver of HER2-positive breast cancer, a highly aggressive subtype requiring precise diagnosis and targeted therapy. Immunohistochemistry…

图像与视频处理 · 电气工程与系统科学 2026-03-10 Sara Rehmat , Hafeez Ur Rehman , Byeong-Gwon Kang , Sarra Ayouni , Yunyoung Nam

Breast cancer is the most common cancer among women worldwide. The human epidermal growth factor receptor 2 (HER2) with immunohistochemical (IHC) is widely used for pathological evaluation to provide the appropriate therapy for patients…

定量方法 · 定量生物学 2022-03-08 Zichen Zhang , Lang Wang , Shuhao Wang
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