相关论文: Neuronal coupling by endogenous electric fields: C…

Cable theory has been developed over the last decades, usually assuming that the extracellular space around membranes is a perfect resistor. However, extracellular media may display more complex electrical properties due to various…

Neurons in the nervous system are submitted to distinct sources of noise, such as ionic-channel and synaptic noise, which introduces variability in their responses to repeated presentations of identical stimuli. This motivates the use of…

Experimental data suggest that some classes of spiking neurons in the first layers of sensory systems are electrically coupled via gap junctions or ephaptic interactions. When the electrical coupling is removed, the response function…

This technical note presents a framework for investigating the underlying mechanisms of neurovascular coupling in the human brain using multi-modal magnetoencephalography (MEG) and functional magnetic resonance (fMRI) neuroimaging data.…

We study the stochastic dynamics of strongly-coupled excitable elements on a tree network. The peripheral nodes receive independent random inputs which may induce large spiking events propagating through the branches of the tree and leading…

We investigate states of enhanced activity in a biological neuronal network composed of pulse-coupled oscillators. The synaptic couplings between the neurons are dynamic, modeling spike time dependent plasticity. The network exhibits…

We continue the work of a series of previous studies of a mathematical model that describes the mean-field limit behavior of a homogeneous network of excitatory point spiking neurons. Contrary to other models, here noise is intrinsic to the…

As an emerging technology, transcranial focused ultrasound has been demonstrated to successfully evoke motor responses in mice, rabbits, and sensory/motor responses in humans. Yet, the spatial resolution of ultrasound does not allow for…

Spontaneous cortical population activity exhibits a multitude of oscillatory patterns, which often display synchrony during slow-wave sleep or under certain anesthetics and stay asynchronous during quiet wakefulness. The mechanisms behind…

Neurostimulation using weak electric fields has generated excitement in recent years due to its potential as a medical intervention. However, study of this stimulation modality has been hampered by inconsistent results and large variability…

Electrical signaling in the brain plays a vital role to our existence but at the same time, the fundamental mechanism of this propagation is undeciphered. Notable advancements have been made in the numerical modeling supplementing the…

The alignment of cell-cell junctions and associated cortical actomyosin across multiple cells to form supracellular cables in an epithelium is an example of the long range tissue organization that drives morphogenesis. Here we demonstrate…

The collective behavior of cortical neurons is strongly affected by the presence of noise at the level of individual cells. In order to study these phenomena in large-scale assemblies of neurons, we consider networks of firing-rate neurons…

A question of cooperative effects in auditory brain processing on various space- and time-scales is addressed. The experimental part of our study is based on Multichannel Magnetoencephalography recordings in normal human subjects. Left,…

The functional significance of correlations between action potentials of neurons is still a matter of vivid debates. In particular it is presently unclear how much synchrony is caused by afferent synchronized events and how much is…

Neurons have the capability of transforming information from a digital signal at the dendrites of the presynaptic termi- nal to an analogous wave at the synaptic cleft and back to a digital pulse when they achieve the required voltage for…

Synaptic plasticity and neuron cross-talk are some of the important key mechanisms underlying formation of dynamic clusters of active neurons. The essence of this study is to model and decipher the mechanism of emergence of a task-specific…

Neurons in many brain areas can develop pronounced depolarized state of membrane potential (up state) in addition to the normal hyperpolarized down state near the resting potential. The influence of the up state on signal encoding, however,…

The interplay between excitatory and inhibitory neurons imparts rich functions of the brain. To understand the underlying synaptic mechanisms, a fundamental approach is to study the dynamics of excitatory and inhibitory conductances of each…

Pulse-coupled spiking neural networks are a powerful tool to gain mechanistic insights into how neurons self-organize to produce coherent collective behavior. These networks use simple spiking neuron models, such as the $\theta$-neuron or…