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When the same set of genes appear in two top ranking gene lists in two different studies, it is often of interest to estimate the probability for this being a chance event. This overlapping probability is well known to follow the…

定量方法 · 定量生物学 2009-11-09 Wen Fury , Franak Batliwalla , Peter K. Gregersen , Wentian Li

This paper proposes nonparametric two-sample tests for the direct comparison of the probabilities of a particular transition between states of a continuous time nonhomogeneous Markov process with a finite state space. The proposed tests are…

统计方法学 · 统计学 2020-02-24 Giorgos Bakoyannis

Model averaging is an important alternative to model selection with attractive prediction accuracy. However, its application to high-dimensional data remains under-explored. We propose a high-dimensional model averaging method via…

统计理论 · 数学 2025-06-11 Zhengyan Wan , Fang Fang , Binyan Jiang

An electrocardiogram (ECG) monitors the electrical activity generated by the heart and is used to detect fatal cardiovascular diseases (CVDs). Conventionally, to capture the precise electrical activity, clinical experts use multiple-lead…

医学物理 · 物理学 2023-07-24 Ekansh Chauhan , Swathi Guptha , Likith Reddy , Bapi Raju

Parity check matrices (PCMs) are used to define linear error correcting codes and ensure reliable information transmission over noisy channels. The set of codewords of such a code is the null space of this binary matrix. We consider the…

Homomorphic encryption (HE) is a promising technique used for privacy-preserving computation. Since HE schemes only support primitive polynomial operations, homomorphic evaluation of polynomial approximations for non-polynomial functions…

密码学与安全 · 计算机科学 2024-05-27 John Chiang

Magnitude is a numerical invariant of enriched categories, including in particular metric spaces as $[0,\infty)$-enriched categories. We show that in many cases magnitude can be categorified to a homology theory for enriched categories,…

代数拓扑 · 数学 2021-11-10 Tom Leinster , Michael Shulman

We present nonparametric algorithms for estimating optimal individualized treatment rules. The proposed algorithms are based on the XGBoost algorithm, which is known as one of the most powerful algorithms in the machine learning literature.…

机器学习 · 统计学 2020-02-04 Duzhe Wang , Haoda Fu , Po-Ling Loh

We present a mixed-precision benchmark called HPL-MxP that uses both a lower-precision LU factorization with a non-stationary iterative refinement based on GMRES. We evaluate the numerical stability of one of the methods of generating the…

数值分析 · 数学 2025-09-25 Jack Dongarra , Piotr Luszczek

Selection HHs are randomised search methodologies which choose and execute heuristics during the optimisation process from a set of low-level heuristics. A machine learning mechanism is generally used to decide which low-level heuristic…

神经与进化计算 · 计算机科学 2019-05-16 Andrei Lissovoi , Pietro S. Oliveto , John Alasdair Warwicker

A matching in a hypergraph $\mathcal{H}$ is a set of pairwise disjoint hyperedges. The matching number $\nu(\mathcal{H})$ of $\mathcal{H}$ is the size of a maximum matching in $\mathcal{H}$. A subset $D$ of vertices of $\mathcal{H}$ is a…

组合数学 · 数学 2016-11-22 Erfang Shan , Yanxia Dong , Liying Kang , Shan Li

The Expectation--Maximization (EM) algorithm is a simple meta-algorithm that has been used for many years as a methodology for statistical inference when there are missing measurements in the observed data or when the data is composed of…

机器学习 · 统计学 2022-11-15 Hideitsu Hino , Shotaro Akaho , Noboru Murata

Motivation: Recent advances in high-throughput sequencing (HTS) have made it possible to monitor genomes in great detail. New experiments not only use HTS to measure genomic features at one time point but to monitor them changing over time…

种群与进化 · 定量生物学 2014-09-19 Hande Topa , Ágnes Jónás , Robert Kofler , Carolin Kosiol , Antti Honkela

Large Language Models (LLMs) have shown promise as robotic planners but often struggle with long-horizon and complex tasks, especially in specialized environments requiring external knowledge. While hierarchical planning and…

人工智能 · 计算机科学 2025-04-08 Cristina Cornelio , Flavio Petruzzellis , Pietro Lio

The little Higgs idea is an alternative to supersymmetry as a solution to the gauge hierarchy problem. In this note, I review various little Higgs models and their phenomenology with emphases on the precision electroweak constraints in…

高能物理 - 唯象学 · 物理学 2009-11-11 Mu-Chun Chen

Hypertension (HPT) refers to a condition where the pressure exerted on the walls of arteries by blood pumped from the heart to the body reaches levels that can lead to various ailments. Annually, a significant number of lives are lost…

信号处理 · 电气工程与系统科学 2023-11-08 Yunus Emre Erdoğan , Ali Narin , Walid Hariri

While large language models (LLMs) are increasingly used as automated heuristic designers for vehicle routing problems (VRPs), current state-of-the-art methods predominantly rely on prompting massive, general-purpose models like GPT-4. This…

机器学习 · 计算机科学 2025-10-14 Rongjie Zhu , Cong Zhang , Zhiguang Cao

Factor analysis, a classical multivariate statistical technique is popularly used as a fundamental tool for dimensionality reduction in statistics, econometrics and data science. Estimation is often carried out via the Maximum Likelihood…

最优化与控制 · 数学 2018-01-19 Koulik Khamaru , Rahul Mazumder

Stochastic network models play a central role across a wide range of scientific disciplines, and questions of statistical inference arise naturally in this context. In this paper we investigate goodness-of-fit and two-sample testing…

统计理论 · 数学 2026-03-27 Subhro Ghosh , Rathindra Nath Karmakar , Samriddha Lahiry

To gain a comprehensive view of what the LHC tells us about physics beyond the Standard Model (BSM), it is crucial that different BSM-sensitive analyses can be combined. But in general, search analyses are not statistically orthogonal, so…

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