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Densely packed, motile bacteria can adopt collective states not seen in conventional, passive materials. These states remain in many ways mysterious, and their physical characterization can aid our understanding of natural bacterial…

While it is commonly observed that the shape dynamics of mammalian cells can undergo large random fluctuations, theoretical models aiming at capturing cell mechanics often focus on the deterministic part of the motion. In this paper, we…

生物物理 · 物理学 2021-04-07 Vikram Deshpande , Antonio DeSimone , Robert McMeeking , Pierre Recho

The near-surface swimming patterns of bacteria are strongly determined by the hydrodynamic interactions between bacteria and the surface, which trap bacteria in smooth circular trajectories that lead to inefficient surface exploration.…

The dynamics of cellular aggregates is driven by the interplay of mechanochemical processes and cellular activity. Although deterministic models may capture mechanical features, local chemical fluctuations trigger random cell responses,…

软凝聚态物质 · 物理学 2024-01-17 Ana Carpio , Elena Cebrian

Collections of persistently moving active particles are an example of a nonequilibrium heat bath. One way to study the nature of nonequilibrium fluctuations in such systems is to follow the dynamics of an embedded probe particle. With this…

统计力学 · 物理学 2023-12-13 Pritha Dolai , Aditya Singh Rajput , K. Vijay Kumar

In this work, we present a multiscale kinetic framework for consensus-based image segmentation. By interpreting an image as a system of interacting particles, each pixel is characterised by its spatial position and an internal feature…

计算机视觉与模式识别 · 计算机科学 2026-05-28 Horacio Tettamanti , Giulia Guicciardi , Mattia Zanella

The biomolecules in and around a living cell -- proteins, nucleic acids, lipids, carbohydrates -- continuously sample myriad conformational states that are thermally accessible at physiological temperatures. Simultaneously, a given…

生物大分子 · 定量生物学 2014-07-15 Cameron Mura , Charles E. McAnany

Active transport of biomolecular condensates and cell migration in collectives are fundamental to development, homeostasis, and processes such as cancer progression, wound healing, and infection response. Yet how these assemblies are…

软凝聚态物质 · 物理学 2025-10-24 Hossein Vahid , Jens-Uwe Sommer , Abhinav Sharma

The interplay between bacterial chromosome organization and functions such as transcription and replication can be studied in increasing detail using novel experimental techniques. Interpreting the resulting quantitative data, however, can…

生物物理 · 物理学 2023-12-18 Janni Harju , Chase P. Broedersz

Bacterial colonies are abundant on living and nonliving surfaces and are known to mediate a broad range of processes in ecology, medicine, and industry. Although extensively researched, from single cells to demographic scales, a…

软凝聚态物质 · 物理学 2018-09-14 Zhihong You , Daniel J. G. Pearce , Anupam Sengupta , Luca Giomi

Current state-of-the-art methods for skeleton-based temporal action segmentation are predominantly supervised and require annotated data, which is expensive to collect. In contrast, existing unsupervised temporal action segmentation methods…

计算机视觉与模式识别 · 计算机科学 2025-08-07 Uzay Gökay , Federico Spurio , Dominik R. Bach , Juergen Gall

We present a new algorithm based on a Cartesian mesh for the numerical approximation of kinetic models for chemosensitive movements set in an arbitrary geometry. We investigate the influence of the geometry on the collective behavior of…

数值分析 · 数学 2013-03-12 Francis Filbet , Chang Yang

Cellular composition prediction, i.e., predicting the presence and counts of different types of cells in the tumor microenvironment from a digitized image of a Hematoxylin and Eosin (H&E) stained tissue section can be used for various tasks…

定量方法 · 定量生物学 2021-08-27 Muhammad Dawood , Kim Branson , Nasir M. Rajpoot , Fayyaz ul Amir Afsar Minhas

Active networks made of biopolymers and motor proteins are valuable bioinspired systems that have been used in the last decades to study the cytoskeleton and its self-organization under mechanical stimulation. Different techniques are…

软凝聚态物质 · 物理学 2023-05-15 Vahid Nasirimarekani , Olinka Ramìrez-Soto , Stefan Karpitschka , Isabella Guido

Living cells dynamically modulate the local morphologies of their actin cytoskeletons to perform biological functions, including force transduction, intracellular transport, and cell division. A major challenge is to understand how diverse…

生物物理 · 物理学 2018-12-07 Simon L. Freedman , Glen M. Hocky , Shiladitya Banerjee , Aaron R. Dinner

Action prediction is to recognize the class label of an ongoing activity when only a part of it is observed. In this paper, we focus on online action prediction in streaming 3D skeleton sequences. A dilated convolutional network is…

计算机视觉与模式识别 · 计算机科学 2019-04-04 Jun Liu , Amir Shahroudy , Gang Wang , Ling-Yu Duan , Alex C. Kot

The mechanical properties of vertebrate bone are largely determined by a process which involves the complex interplay of three different cell types. This process is called {\it bone remodeling}, and occurs asynchronously at multiple sites…

组织与器官 · 定量生物学 2011-11-30 Marc Ryser , Svetlana V. Komarova , Nilima Nigam

Growing tissue and bacterial colonies are active matter systems where cell divisions and cellular motion generate active stress. Although they operate in the non-equilibrium regime, these biological systems can form large-scale ordered…

生物物理 · 物理学 2019-05-28 Yusuf Ilker Yaman , Esin Demir , Roman Vetter , Askin Kocabas

We introduce a novel musculoskeletal model of a dog, procedurally generated from accurate 3D muscle meshes. Accompanying this model is a motion capture-based locomotion task compatible with a variety of control algorithms, as well as an…

机器人学 · 计算机科学 2025-07-01 Vittorio La Barbera , Steven Bohez , Leonard Hasenclever , Yuval Tassa , John R. Hutchinson

Biofilms are spatially organized microorganism colonies embedded in a self-produced matrix, conferring to the microbial community resistance to environmental stresses. Motile bacteria have been observed swimming in the matrix of pathogenic…

定量方法 · 定量生物学 2022-05-24 Guillaume Ravel , Michel Bergmann , Alain Trubuil , Julien Deschamps , Romain Briandet , Simon Labarthe