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Feature selection is a preprocessing step which plays a crucial role in the domain of machine learning and data mining. Feature selection methods have been shown to be effctive in removing redundant and irrelevant features, improving the…

机器学习 · 计算机科学 2021-06-01 Xiongshi Deng , Min Li , Lei Wang , Qikang Wan

Directed evolution is an iterative laboratory process of designing proteins with improved function by iteratively synthesizing new protein variants and evaluating their desired property with expensive and time-consuming biochemical…

机器学习 · 计算机科学 2025-09-08 Matouš Soldát , Jiří Kléma

2-in-1 design (Chen et al. 2018) is becoming popular in oncology drug development, with the flexibility of using different endpoints at different decision time. Based on the observed interim data, sponsors choose either to seamlessly…

统计方法学 · 统计学 2024-04-15 Runjia Li , Liwen Wu , Rachael Liu , Jianchang Lin

Deploying dense retrieval models efficiently is becoming increasingly important across various industries. This is especially true for enterprise search services, where customizing search engines to meet the time demands of different…

信息检索 · 计算机科学 2024-01-24 Chen Huang , Duanyu Feng , Wenqiang Lei , Jiancheng Lv

The problem of adaptive sampling for estimating probability mass functions (pmf) uniformly well is considered. Performance of the sampling strategy is measured in terms of the worst-case mean squared error. A Bayesian variant of the…

统计方法学 · 统计学 2020-12-09 Dhruva Kartik , Neeraj Sood , Urbashi Mitra , Tara Javidi

We briefly overview the new features of PlanetPack2, the forthcoming update of PlanetPack, which is a software tool for exoplanets detection and characterization from Doppler radial velocity data. Among other things, this major update…

天体物理仪器与方法 · 物理学 2015-07-15 Roman V. Baluev

We present a provable, sampling-based approach for generating compact Convolutional Neural Networks (CNNs) by identifying and removing redundant filters from an over-parameterized network. Our algorithm uses a small batch of input data…

机器学习 · 计算机科学 2020-03-24 Lucas Liebenwein , Cenk Baykal , Harry Lang , Dan Feldman , Daniela Rus

A new inversion method for determining near-surface shear currents from a measured wave spectrum is introduced. The method is straightforward to implement and starts from the existing state-of-the-art technique of assigning effective depths…

大气与海洋物理 · 物理学 2020-02-19 Benjamin K. Smeltzer , Eirik Æsøy , Anna Ådnøy , Simen Å. Ellingsen

We introduce an online outlier detection algorithm to detect outliers in a sequentially observed data stream. For this purpose, we use a two-stage filtering and hedging approach. In the first stage, we construct a multi-modal probability…

机器学习 · 计算机科学 2018-03-13 Mohammadreza Mohaghegh Neyshabouri , Suleyman Serdar Kozat

Weak purifying selection, acting on many linked mutations, may play a major role in shaping patterns of molecular evolution in natural populations. Yet efforts to infer these effects from DNA sequence data are limited by our incomplete…

种群与进化 · 定量生物学 2012-10-17 Benjamin H Good , Michael M Desai

Diversity is an important factor in evolutionary algorithms to prevent premature convergence towards a single local optimum. In order to maintain diversity throughout the process of evolution, various means exist in literature. We analyze…

神经与进化计算 · 计算机科学 2018-10-31 Thomas Gabor , Lenz Belzner , Claudia Linnhoff-Popien

In this paper, we investigate dynamic feature selection within multivariate time-series scenario, a common occurrence in clinical prediction monitoring where each feature corresponds to a bio-test result. Many existing feature selection…

机器学习 · 计算机科学 2024-05-31 Yutong Chen , Jiandong Gao , Ji Wu

In the past decades, the rapid growth of computer and database technologies has led to the rapid growth of large-scale datasets. On the other hand, data mining applications with high dimensional datasets that require high speed and accuracy…

机器学习 · 计算机科学 2020-08-11 Mehrdad Rostami , Kamal Berahmand , Saman Forouzandeh

Feature selection has drawn much attention over the last decades in machine learning because it can reduce data dimensionality while maintaining the original physical meaning of features, which enables better interpretability than feature…

机器学习 · 计算机科学 2022-09-27 Yiwen Liao , Jochen Rivoir , Raphaël Latty , Bin Yang

We propose Splinter, a new technique for proving properties of heap-manipulating programs that marries (1) a new separation logic-based analysis for heap reasoning with (2) an interpolation-based technique for refining heap-shape invariants…

计算机科学中的逻辑 · 计算机科学 2015-01-20 Aws Albarghouthi , Josh Berdine , Byron Cook , Zachary Kincaid

This works extends the Random Embedding Bayesian Optimization approach by integrating a warping of the high dimensional subspace within the covariance kernel. The proposed warping, that relies on elementary geometric considerations, allows…

最优化与控制 · 数学 2015-03-19 Mickaël Binois , David Ginsbourger , Olivier Roustant

It is now practically the norm for data to be very high dimensional in areas such as genetics, machine vision, image analysis and many others. When analyzing such data, parametric models are often too inflexible while nonparametric…

统计方法学 · 统计学 2011-05-31 Abhishek Bhattacharya , Garritt Page , David Dunson

Pulmonary nodule detection plays an important role in lung cancer screening with low-dose computed tomography (CT) scans. It remains challenging to build nodule detection deep learning models with good generalization performance due to…

计算机视觉与模式识别 · 计算机科学 2020-02-10 Yuemeng Li , Yong Fan

Background: Significance analysis plays a major role in identifying and ranking genes, transcription factor binding sites, DNA methylation regions, and other high-throughput features for association with disease. We propose a new approach,…

统计方法学 · 统计学 2017-01-10 Andrew E. Jaffe , John D. Storey , Hongkai Ji , Jeffrey T. Leek

This paper presents a method for analysis of the vote space created from the local features extraction process in a multi-detection system. The method is opposed to the classic clustering approach and gives a high level of control over the…

计算机视觉与模式识别 · 计算机科学 2016-01-06 Grzegorz Kurzejamski , Jacek Zawistowski , Grzegorz Sarwas