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We generalize the Cable Model to describe the transport characteristics of the gap junctions coupling adjacent cells in the heart muscle. Our model takes into account recent experimental information about the time dependence of the…

斑图形成与孤子 · 物理学 2018-09-05 Isabel M. Irurzun , Magdalena M. Defeo

We address a question on the effect of common stochastic inputs on the correlation of the spikes trains of two neurons when they are possibly nonidentical and are coupled through direct connections. We show that the change in the…

神经元与认知 · 定量生物学 2013-04-24 E. Bolhasani , Y. Azizi , A. Valizadeh

Synchronization is studied in a spatially-distributed network of weekly-coupled, excitatory neurons of Hodgkin-Huxley type. All neurons are coupled to each other synaptically with a fixed time delay and a coupling strength inversely…

软凝聚态物质 · 物理学 2007-05-23 Yuqing Wang , Z. D. Wang , Y. -X. Li , X. Pei

The activity of neurons is correlated, and this correlation affects how the brain processes information. We study the neural circuit mechanisms of correlations by analyzing a network model characterized by strong and heterogeneous…

神经元与认知 · 定量生物学 2012-12-03 Alberto Bernacchia , Xiao-Jing Wang

The in silico simulations are widely used in contemporary systems biology including the analysis of nerve pulse propagation. As known from numerous experiments, the propagation of an action potential is accompanied by mechanical and thermal…

生物物理 · 物理学 2020-09-21 Jüri Engelbrecht , Kert Tamm , Tanel Peets

We study synchronisation properties of networks of coupled dynamical systems with interaction akin to diffusion. We assume that the isolated node dynamics possesses a forward invariant set on which it has a bounded Jacobian, then we…

动力系统 · 数学 2015-03-30 Tiago Pereira , Jaap Eldering , Martin Rasmussen , Alexei Veneziani

The saltatory propagation of action potentials on myelinated axons is conventionally explained by the mechanism employing local circuit ionic current flows between nodes of Ranvier. Under this framework, the myelin sheath with up to 100…

神经元与认知 · 定量生物学 2012-10-09 Jiongwei Xue , Shengyong Xu

We study a network model of two conductance-based pacemaker neurons of differing natural frequency, coupled with either mutual excitation or inhibition, and receiving shared random inhibitory synaptic input. The networks may phase-lock…

神经元与认知 · 定量生物学 2009-11-13 Ramana Dodla , Charles J. Wilson

Mirror neurons are a class of neurons that activate both when an individual observes an action and when they perform the same action. This mechanism reveals a fundamental interplay between action understanding and embodied execution,…

人工智能 · 计算机科学 2025-09-26 Wentao Zhu , Zhining Zhang , Yuwei Ren , Yin Huang , Hao Xu , Yizhou Wang

We introduce a method for computing probabilities for spontaneous activity and propagation fail- ure of the action potential in spatially extended, conductance-based neuronal models subject to channel noise, based on statistical properties…

神经元与认知 · 定量生物学 2020-01-16 Martin Sauer , Wilhelm Stannat

We investigate networks of automata that synchronise over common action labels. A graph synchronisation topology between the automata is defined in such a way that two automata are connected iff they can synchronise over an action. We show…

计算机科学中的逻辑 · 计算机科学 2020-12-10 Laure Petrucci , Michał Knapik

The dynamics of three mutually coupled cortical neurons with time delays in the coupling are explored numerically and analytically. The neurons are coupled in a line, with the middle neuron sending a somewhat stronger projection to the…

混沌动力学 · 物理学 2011-01-25 Alexandra S. Landsman , Ira B. Schwartz

We show that the unavoidable increase in neuronal response latency to ongoing stimulation serves as a nonuniform gradual stretching of neuronal circuit delay loops and emerges as an essential mechanism in the formation of various types of…

神经元与认知 · 定量生物学 2012-12-07 Roni Vardi , Reut Timor , Shimon Marom , Moshe Abeles , Ido Kanter

The oscillatory nature of the cortical local field potential (LFP) is commonly interpreted as a reflection of synchronized network activity, but its relationship to observed transient coincident firing of neurons on the millisecond…

神经元与认知 · 定量生物学 2011-11-24 Michael Denker , Sébastien Roux , Henrik Lindén , Markus Diesmann , Alexa Riehle , Sonja Grün

Synchronization of networked oscillators is known to depend fundamentally on the interplay between the dynamics of the graph's units and the microscopic arrangement of the network's structure. For non identical elements, the lack of…

适应与自组织系统 · 物理学 2016-01-20 A. Navas , J. A. Villacorta-Atienza , I. Leyva , J. A. Almendral , I. Sendiña-Nadal , S. Boccaletti

This article investigates the emergence of phase synchronization in a network of randomly connected neurons by chemical synapses. The study uses the classic Hodgkin-Huxley model to simulate the neuronal dynamics under the action of a train…

Novel experimental techniques reveal the simultaneous activity of larger and larger numbers of neurons. As a result there is increasing interest in the structure of cooperative -- or correlated -- activity in neural populations, and in the…

神经元与认知 · 定量生物学 2015-05-30 James Trousdale , Yu Hu , Eric Shea-Brown , Krešimir Josić

Does synchronization between action potentials from different neurons in the visual system play a substantial role in solving the binding problem? The binding problem can be studied quantitatively in the broader framework of the information…

生物物理 · 物理学 2007-05-23 Simon R. Schultz , Huw D. R. Golledge , Stefano Panzeri

Cell movement and intercellular signaling occur simultaneously during the development of tissues, but little is known about how movement affects signaling. Previous theoretical studies have shown that faster moving cells favor…

细胞行为 · 定量生物学 2012-05-09 Koichiro Uriu , Saul Ares , Andrew C. Oates , Luis G. Morelli

When brain signals are recorded in an electroencephalogram or some similar large-scale record of brain activity, oscillatory patterns are typically observed that are thought to reflect the aggregate electrical activity of the underlying…

神经元与认知 · 定量生物学 2013-06-04 Andre Nathan , Valmir C. Barbosa