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During multiple testing, researchers often adjust their alpha level to control the familywise error rate for a statistical inference about a joint union alternative hypothesis (e.g., "H1,1 or H1,2"). However, in some cases, they do not make…

统计方法学 · 统计学 2024-04-04 Mark Rubin

Test-negative designs with added controls have recently been proposed to study COVID-19. An individual is test-positive or test-negative accordingly if they took a test for a disease but tested positive or tested negative. Adding a control…

统计方法学 · 统计学 2020-05-15 Bikram Karmakar , Dylan Small

Most scientific disciplines use significance testing to draw conclusions about experimental or observational data. This classical approach provides a theoretical guarantee for controlling the number of false positives across a set of…

应用统计 · 统计学 2023-03-06 Stanley E. Lazic

Bonferroni's correction is a popular tool to address multiplicity but is notorious for its low power when tests are dependent. This paper proposes a practical modification of Bonferroni's correction when test statistics are jointly normal…

统计方法学 · 统计学 2026-02-24 Caleb Hiltunen , Yeonwoo Rho

Empirical research in the social and medical sciences frequently involves testing multiple hypotheses simultaneously, increasing the risk of false positives due to chance. Classical multiple testing procedures, such as the Bonferroni…

计量经济学 · 经济学 2025-07-29 Sebastian Calonico , Sebastian Galiani

Recent advancements in language models have led to significant improvements in mathematical reasoning across various benchmarks. However, most of these benchmarks rely on automatic evaluation methods that only compare final answers using…

计算与语言 · 计算机科学 2025-09-19 Yu Wang , Nan Yang , Liang Wang , Furu Wei , Fuli Feng

Correlated observations are ubiquitous phenomena in a plethora of scientific avenues. Tackling this dependence among test statistics has been one of the pertinent problems in simultaneous inference. However, very little literature exists…

统计理论 · 数学 2024-11-20 Monitirtha Dey

Multiple hypothesis testing practices vary widely, without consensus on which are appropriate when. This paper provides an economic foundation for these practices designed to capture leading examples, such as regulatory approval on the…

综合经济学 · 经济学 2026-02-19 Davide Viviano , Kaspar Wuthrich , Paul Niehaus

Nonparametric generalized likelihood ratio test is popularly used for model checking for regressions. However, there are two issues that may be the barriers for its powerfulness. First, the bias term in its liming null distribution causes…

统计方法学 · 统计学 2015-07-23 Cuizhen Niu , Xu Guo , Lixing Zhu

In confirmatory clinical trials with small sample sizes, hypothesis tests based on asymptotic distributions are often not valid and exact non-parametric procedures are applied instead. However, the latter are based on discrete test…

统计方法学 · 统计学 2018-02-22 Robin Ristl , Dong Xi , Ekkehard Glimm , Martin Posch

When dealing with the problem of simultaneously testing a large number of null hypotheses, a natural testing strategy is to first reduce the number of tested hypotheses by some selection (screening or filtering) process, and then to…

统计方法学 · 统计学 2017-03-21 Wenge Guo , Joseph P. Romano

The standard paradigm for confirmatory clinical trials is to compare experimental treatments with a control, for example the standard of care or a placebo. However, it is not always the case that a suitable control exists. Efficient…

统计方法学 · 统计学 2024-10-29 Thomas Burnett , Thomas Jaki

Over the last decade there has been increasing concern about the biases embodied in traditional evaluation methods for Natural Language Processing/Learning, particularly methods borrowed from Information Retrieval. Without knowledge of the…

人工智能 · 计算机科学 2015-04-06 David M. W. Powers

The present study investigates the performance of several statistical tests to detect publication bias in diagnostic meta-analysis by means of simulation. While bivariate models should be used to pool data from primary studies in diagnostic…

统计方法学 · 统计学 2022-11-24 Paul-Christian Bürkner , Philipp Doebler

A series of monte carlo studies were performed to compare the behavior of some alternative procedures for reasoning under uncertainty. The behavior of several Bayesian, linear model and default reasoning procedures were examined in the…

人工智能 · 计算机科学 2013-03-26 Paul E. Lehner , Azar Sadigh

This paper examines the use of Monte Carlo simulations to understand statistical concepts in A/B testing and Randomized Controlled Trials (RCTs). We discuss the applicability of simulations in understanding false positive rates and estimate…

应用统计 · 统计学 2024-11-12 Márton Trencséni

Statistical model checking delivers quantitative verification results with statistical guarantees by applying Monte Carlo simulation to formal models. It scales to model sizes and model types that are out of reach for exhaustive, analytical…

计算机科学中的逻辑 · 计算机科学 2025-11-18 Pedro R. D'Argenio , Arnd Hartmanns , Patrick Wienhöft , Mark van Wijk

It is quite common in modern research, for a researcher to test many hypotheses. The statistical (frequentist) hypothesis testing framework, does not scale with the number of hypotheses in the sense that naively performing many hypothesis…

统计方法学 · 统计学 2013-06-26 Jonathan Rosenblatt

Random-effects meta-analyses have been widely applied in evidence synthesis for various types of medical studies. However, standard inference methods (e.g. restricted maximum likelihood estimation) usually underestimate statistical errors…

统计方法学 · 统计学 2019-05-13 Shonosuke Sugasawa , Hisashi Noma

When comparing multiple groups in clinical trials, we are not only interested in whether there is a difference between any groups but rather the location. Such research questions lead to testing multiple individual hypotheses. To control…

统计方法学 · 统计学 2025-01-08 Ina Dormuth , Carolin Herrmann , Frank Konietschke , Markus Pauly , Matthias Wirth , Marc Ditzhaus
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