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Mendelian randomization (MR) has been a popular method in genetic epidemiology to estimate the effect of an exposure on an outcome using genetic variants as instrumental variables (IV), with two-sample summary-data MR being the most…

统计方法学 · 统计学 2021-06-08 Sheng Wang , Hyunseung Kang

Alcohol misuse is a key target of public health strategies aimed at reducing cardiovascular risk. The effect of excessive alcohol consumption on blood pressure may vary systematically with individuals' unobserved propensity to engage in…

统计方法学 · 统计学 2026-03-11 Ashish Patel , Francis J DiTraglia , Stephen Burgess

Combining information from multiple samples is often needed in biomedical and economic studies, but the differences between these samples must be appropriately taken into account in the analysis of the combined data. We study estimation for…

统计方法学 · 统计学 2018-08-14 Heng Shu , Zhiqiang Tan

This paper introduces measures for how each moment contributes to the precision of parameter estimates in GMM settings. For example, one of the measures asks what would happen to the variance of the parameter estimates if a particular…

计量经济学 · 经济学 2020-01-09 Bo Honore , Thomas Jorgensen , Aureo de Paula

Statistical shape models (SSMs) are state-of-the-art medical image analysis tools for extracting and explaining features across a set of biological structures. However, a principled and robust way to combine shape and pose features has been…

计算机视觉与模式识别 · 计算机科学 2021-12-10 Jean-Rassaire Fouefack , Bhushan Borotikar , Tania S. Douglas , Valérie Burdin , Tinashe E. M. Mutsvangwa

Variable selection remains a difficult problem, especially for generalized linear mixed models (GLMMs). While some frequentist approaches to simultaneously select joint fixed and random effects exist, primarily through the use of…

统计方法学 · 统计学 2024-12-03 Feng Ding , Ian Laga

Behavioral science researchers have shown strong interest in disaggregating within-person relations from between-person differences (stable traits) using longitudinal data. In this paper, we propose a method of within-person variability…

统计方法学 · 统计学 2025-01-08 Satoshi Usami

The global sensitivity analysis method, used to quantify the influence of uncertain input variables on the response variability of a numerical model, is applicable to deterministic computer code (for which the same set of input variables…

统计方法学 · 统计学 2009-06-08 Bertrand Iooss , Mathieu Ribatet , Amandine Marrel

We propose a procedure for imputing missing values of time-dependent covariates in a survival model using fully conditional specification. Specifically, we focus on imputing missing values of a longitudinal marker in joint modeling of the…

统计方法学 · 统计学 2024-03-29 Havi Murad , Nirit Agay , Rachel Dankner

Generalized method of moments estimators based on higher-order moment conditions derived from independent shocks can be used to identify and estimate the simultaneous interaction in structural vector autoregressions. This study highlights…

计量经济学 · 经济学 2023-10-13 Sascha A. Keweloh

The Generalized Additive Model (GAM) is a powerful tool and has been well studied. This model class helps to identify additive regression structure. Via available test procedures one may identify the regression structure even sharper if…

统计方法学 · 统计学 2020-09-11 Rong Liu , Wolfgang Karl Härdle

In genetic association studies, detecting phenotype-genotype association is a primary goal. We assume that the relationship between the data -phenotype, genetic markers and environmental covariates - can be modelled by a generalized linear…

统计方法学 · 统计学 2020-04-13 K. K. Halle , Ø. Bakke , S. Djurovic , A. Bye , E. Ryeng , U. Wisløff , O. A. Andreassen , M. Langaas

When studying the association between treatment and a clinical outcome, a parametric multivariable model of the conditional outcome expectation is often used to adjust for covariates. The treatment coefficient of the outcome model targets a…

统计方法学 · 统计学 2026-05-07 Antonio Remiro-Azócar , Anna Heath , Gianluca Baio

We study the problem of estimating causal effects under hidden confounding in the following unpaired data setting: we observe some covariates $X$ and an outcome $Y$ under different experimental conditions (environments) but do not observe…

机器学习 · 统计学 2026-01-22 Felix Schur , Niklas Pfister , Peng Ding , Sach Mukherjee , Jonas Peters

Automatic estimation of piano fingering is important for understanding the computational process of music performance and applicable to performance assistance and education systems. While a natural way to formulate the quality of fingerings…

机器学习 · 计算机科学 2020-01-03 Eita Nakamura , Yasuyuki Saito , Kazuyoshi Yoshii

Causal inference in multivariate time series is challenging due to the fact that the sampling rate may not be as fast as the timescale of the causal interactions. In this context, we can view our observed series as a subsampled version of…

统计方法学 · 统计学 2017-04-11 Alex Tank , Emily B. Fox , Ali Shojaie

Mendelian randomization (MR) is a widely used tool for causal inference in the presence of unmeasured confounders, which uses single nucleotide polymorphisms (SNPs) as instrumental variables to estimate causal effects. However, SNPs often…

统计方法学 · 统计学 2025-04-29 Ruoyu Wang , Haoyu Zhang , Xihong Lin

Structural Health Monitoring (SHM) plays a pivotal role in modern civil engineering, providing critical insights into the health and integrity of infrastructure systems. This work presents a novel multivariate long-term profile monitoring…

应用统计 · 统计学 2025-06-26 Philipp Wittenberg , Alexander Mendler , Sven Knoth , Jan Gertheiss

This paper proposes a simple and efficient estimation procedure for the model with non-ignorable missing data studied by Morikawa and Kim (2016). Their semiparametrically efficient estimator requires explicit nonparametric estimation and so…

统计方法学 · 统计学 2018-01-15 Chunrong Ai , Oliver Linton , Zheng Zhang

There is an increasing interest in estimating heterogeneity in causal effects in randomized and observational studies. However, little research has been conducted to understand heterogeneity in an instrumental variables study. In this work,…

统计方法学 · 统计学 2021-01-20 Michael Johnson , Jiongyi Cao , Hyunseung Kang