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We study a combinatorial problem arising from microarrays synthesis. The synthesis is done by a light-directed chemical process. The objective is to minimize unintended illumination that may contaminate the quality of experiments.…

数据结构与算法 · 计算机科学 2010-11-05 Alexandru Popa , Prudence W. H. Wong , Fencol C. C. Yung

Protein/Peptide microarrays are rapidly gaining momentum in the diagnosis of cancer. High-density and highthroughput peptide arrays are being extensively used to detect tumor biomarkers, examine kinase activity, identify antibodies having…

数据结构与算法 · 计算机科学 2015-03-13 Vamsi Kundeti , Sanguthevar Rajasekaran , Hieu Dinh

We show that the Minimal Length-Bounded L-But problem can be computed in linear time with respect to L and the tree-width of the input graph as parameters. In this problem the task is to find a set of edges of a graph such that after…

数据结构与算法 · 计算机科学 2016-10-25 Dušan Knop , Pavel Dvořák

We study computational complexity of the class of distance-constrained graph labeling problems from the fixed parameter tractability point of view. The parameters studied are neighborhood diversity and clique width. We rephrase the distance…

离散数学 · 计算机科学 2015-12-04 Jiří Fiala , Tomáš Gavenčiak , Dušan Knop , Martin Koutecký , Jan Kratochvíl

The maximum modularity of a graph is a parameter widely used to describe the level of clustering or community structure in a network. Determining the maximum modularity of a graph is known to be NP-complete in general, and in practice a…

数据结构与算法 · 计算机科学 2022-12-22 Kitty Meeks , Fiona Skerman

When considering a graph problem from a parameterized point of view, the parameter chosen is often the size of an optimal solution of this problem (the "standard" parameter). A natural subject for investigation is what happens when we…

计算复杂性 · 计算机科学 2013-10-14 Nicolas Bourgeois , Konrad K. Dabrowski , Marc Demange , Vangelis Th. Paschos

We study the complexity of the problem of searching for a set of patterns that separate two given sets of strings. This problem has applications in a wide variety of areas, most notably in data mining, computational biology, and in…

计算复杂性 · 计算机科学 2016-12-20 Giuseppe Lancia , Luke Mathieson , Pablo Moscato

Given a graph G, a matching is a subset of edges of G that do not share an endpoint. A matching M is uniquely restricted if the subgraph induced by the endpoints of the edges of M has exactly one perfect matching. Given a graph G and a…

数据结构与算法 · 计算机科学 2025-08-19 Juhi Chaudhary , Ignasi Sau , Meirav Zehavi

Combining the techniques of approximation algorithms and parameterized complexity has long been considered a promising research area, but relatively few results are currently known. In this paper we study the parameterized approximability…

数据结构与算法 · 计算机科学 2014-02-18 Michael Lampis

Parameterized complexity enables the practical solution of generally intractable NP-hard problems when certain parameters are small, making it particularly useful in real-world applications. The study of string problems in this framework…

量子物理 · 物理学 2025-10-20 Josh Cudby , Sergii Strelchuk

We consider the well-studied problem of finding a spanning tree with minimum average distance between vertex pairs (called a MAD tree). This is a classic network design problem which is known to be NP-hard. While approximation algorithms…

数据结构与算法 · 计算机科学 2026-04-01 Tom-Lukas Breitkopf , Vincent Froese , Anton Herrmann , André Nichterlein , Camille Richer

Finding the smallest $d$-chain with a specific $(d-1)$-boundary in a simplicial complex is known as the \textsc{Minimum Bounded Chain} (MBC$_d$) problem. The MBC$_d$ problem is NP-hard for all $d\geq 2$. In this paper, we prove that it is…

计算几何 · 计算机科学 2021-08-13 Nello Blaser , Morten Brun , Lars M. Salbu , Erlend Raa Vågset

In this paper, we study the parameterized complexity of local search, whose goal is to find a good nearby solution from the given current solution. Formally, given an optimization problem where the goal is to find the largest feasible…

数据结构与算法 · 计算机科学 2025-12-04 Aditya Anand , Vincent Cohen-Addad , Tommaso d'Orsi , Anupam Gupta , Euiwoong Lee , Debmalya Panigrahi , Sijin Peng

A metro-line crossing minimization problem is to draw multiple lines on an underlying graph that models stations and rail tracks so that the number of crossings of lines becomes minimum. It has several variations by adding restrictions on…

数据结构与算法 · 计算机科学 2013-06-18 Yoshio Okamoto , Yuichi Tatsu , Yushi Uno

A parameterized string (p-string) is a string over an alphabet $(\Sigma_{s} \cup \Sigma_{p})$, where $\Sigma_{s}$ and $\Sigma_{p}$ are disjoint alphabets for static symbols (s-symbols) and for parameter symbols (p-symbols), respectively.…

数据结构与算法 · 计算机科学 2023-08-14 Kento Iseri , Tomohiro I , Diptarama Hendrian , Dominik Köppl , Ryo Yoshinaka , Ayumi Shinohara

The study of genetic map linearization leads to a combinatorial hard problem, called the {\em minimum breakpoint linearization} (MBL) problem. It is aimed at finding a linearization of a partial order which attains the minimum breakpoint…

基因组学 · 定量生物学 2015-02-26 Xin Chen

We study integer linear programs (ILP) of the form $\min\{c^\top x\ \vert\ Ax=b,l\le x\le u,x\in\mathbb Z^n\}$ and analyze their parameterized complexity with respect to their distance to the generalized matching problem, following the…

计算复杂性 · 计算机科学 2025-10-20 Alexandra Lassota , Koen Ligthart

A set $S$ of vertices of a graph is a defensive alliance if, for each element of $S$, the majority of its neighbours is in $S$. We consider the notion of local minimality in this paper. We are interested in locally minimal defensive…

计算复杂性 · 计算机科学 2023-03-06 Ajinkya Gaikwad , Soumen Maity , Shuvam Kant Tripathi

In this paper we study the complexity of the following problems: Given a colored graph X=(V,E,c), compute a minimum cardinality set S of vertices such that no nontrivial automorphism of X fixes all vertices in S. A closely related problem…

计算复杂性 · 计算机科学 2016-06-15 V. Arvind , Frank Fuhlbrück , Johannes Köbler , Sebastian Kuhnert , Gaurav Rattan

Many graph problems were first shown to be fixed-parameter tractable using the results of Robertson and Seymour on graph minors. We show that the combination of finite, computable, obstruction sets and efficient order tests is not just one…

计算复杂性 · 计算机科学 2013-05-15 Michael R. Fellows , Bart M. P. Jansen
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