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Intracellular components explore the cytoplasm via active motor-driven transport in conjunction with passive diffusion. We model the motion of organelles in narrow tubular cells using analytical techniques and numerical simulations to study…

生物物理 · 物理学 2018-04-11 Saurabh Mogre , Elena F. Koslover

To achieve optimal robot behavior in dynamic scenarios we need to consider complex dynamics in a predictive manner. In the vehicle dynamics community, it is well know that to achieve time-optimal driving on low surface, the vehicle should…

机器人学 · 计算机科学 2023-03-28 Zlatan Ajanović , Enrico Regolin , Barys Shyrokau , Hana Ćatić , Martin Horn , Antonella Ferrara

Bacteria track chemical gradients using a biased random walk, a process called chemotaxis. Experiments suggest that bacteria also communicate during this process. Using a mathematical model, we find that sufficiently strong communication…

生物物理 · 物理学 2025-12-18 Soutick Saha , Sean Fancher , Andrew Mugler

We propose a bio-inspired, agent-based approach to describe the natural phenomenon of group chasing in both two and three dimensions. Using a set of local interaction rules we created a continuous-space and discrete-time model with time…

生物物理 · 物理学 2017-05-24 Milán Janosov , Csaba Virágh , Gábor Vásárhelyi , Tamás Vicsek

In this study, we analyse a high-frequency movement dataset for a group of grazing cattle and investigate their spatiotemporal patterns using a simple two-state `stop-and-move' mobility model. We find that the dispersal kernel in the moving…

定量方法 · 定量生物学 2016-03-18 Kun Zhao , Raja Jurdak

In this paper, a distributed convex optimization problem with swarm tracking behavior is studied for continuous-time multi-agent systems. The agents' task is to drive their center to track an optimal trajectory which minimizes the sum of…

最优化与控制 · 数学 2015-07-20 Salar Rahili , Wei Ren , Sheida Ghapani

Motivated by the observation of non-exponential run-time distributions of bacterial swimmers, we propose a minimal phenomenological model for taxis of active particles whose motion is controlled by an internal clock. The ticking of the…

生物物理 · 物理学 2020-07-23 Luis Gómez Nava , Robert Großmann , Marius Hintsche , Carsten Beta , Fernando Peruani

The response of microbes to external signals is mediated by biochemical networks with intrinsic time scales. These time scales give rise to a memory that impacts cellular behaviour. Here we study theoretically the role of cellular memory in…

生物物理 · 物理学 2020-02-14 Adam Gosztolai , Mauricio Barahona

Cells use temporal dynamical patterns to transmit information via signaling pathways. As optimality with respect to the environment plays a fundamental role in biological systems, organisms have evolved optimal ways to transmit information.…

生物物理 · 物理学 2016-12-21 Yoshihiko Hasegawa

Diffusion of tracer particles in the cytoplasm of mammalian cells is often anomalous with a marked heterogeneity even within individual particle trajectories. Despite considerable efforts, the mechanisms behind these observations have…

生物物理 · 物理学 2020-08-05 Adal Sabri , Xinran Xu , Diego Krapf , Matthias Weiss

Nature is in constant flux, so animals must account for changes in their environment when making decisions. How animals learn the timescale of such changes and adapt their decision strategies accordingly is not well understood. Recent…

神经元与认知 · 定量生物学 2018-12-24 Zachary P. Kilpatrick , William R. Holmes , Tahra L. Eissa , Krešimir Josić

Chemotaxis of bacterial swimmers that move in a run-and-turn pattern is well studied in uniform bulk fluid. It is primarily based on modulating the run time in dependence on the swimming direction with respect to the source of…

软凝聚态物质 · 物理学 2025-03-10 Sönke Beier , Veronika Pfeifer , Agniva Datta , Robert Großmann , Carsten Beta

We study a model of cell motility where the condition of optimal trade-off between performance and metabolic cost can be made precise. In this model a steadily crawling fragment is represented by a layer of active gel placed on a frictional…

生物物理 · 物理学 2015-06-18 P. Recho , J. -F. Joanny , L. Truskinovsky

Cells are constantly exposed to diverse stimuli-chemical, mechanical, or electrical-that guide their movement. In physiological conditions, these signals often overlap, as seen during infections, where neutrophils and dendritic cells…

生物物理 · 物理学 2026-03-25 Emiliano Perez Ipiña , Brian A. Camley

Natural systems often exhibit chaotic behavior in their space-time evolution. Systems transiting between chaos and order manifest a potential to compute, as shown with cellular automata and artificial neural networks. We demonstrate that…

计算物理 · 物理学 2025-04-08 Tomáš Vantuch , Ivan Zelinka , Andrew Adamatzky , Norbert Marwan

Noise in transduction of chemotactic stimuli to the flagellar motor of E. coli will affect the random run-and-tumble motion of the cell and the ability to perform chemotaxis. Here we use numerical simulations to show that an intermediate…

细胞行为 · 定量生物学 2012-10-05 Marlo Flores , Thomas S. Shimuzu , Pieter Rein ten Wolde , Filipe Tostevin

This brief proposes a quasi time-fuel optimal control strategy to solve the dynamic tracking problem of unmanned systems when fuel and control input are limited. This kind of motion planning and control strategy could bring the biggest…

科普物理 · 物理学 2021-11-25 Huaihang Zheng , Junzheng Wang , Dawei Shi , Dongchen Liu , Shoukun Wang

Extending the classic works of Berg and Purcell on the biophysics of bacterial chemotaxis, we find the optimal chemotactic strategy for the peritrichous bacterium E. Coli in the high and low signal to noise ratio limits. The optimal…

adap-org · 物理学 2009-10-30 S. P. Strong , B. Freedman , William Bialek , R. Koberle

The behavior of the maximal displacement of a supercritical branching random walk has been a subject of intense studies for a long time. But only recently the case of time-inhomogeneous branching has gained focus. The contribution of this…

概率论 · 数学 2021-12-23 Bastien Mallein , Piotr Miłoś

Efficient navigation in swarms often relies on the emergence of decentralized approaches that minimize traversal time or energy. Stigmergy, where agents modify a shared environment that then modifies their behavior, is a classic mechanism…

神经元与认知 · 定量生物学 2026-01-08 Vishaal Krishnan , L. Mahadevan