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Next generation online and real-time adaptive radiotherapy workflows require precise particle transport simulations in sub-second times, which is unfeasible with current analytical pencil beam algorithms (PBA) or stochastic Monte Carlo (MC)…

医学物理 · 物理学 2022-02-08 Oscar Pastor-Serrano , Zoltán Perkó

We introduce a GPU-accelerated Monte Carlo framework for nonconvex, free-final-time trajectory optimization problems. This framework makes use of the prox-linear method, which belongs to the larger family of sequential convex programming…

最优化与控制 · 数学 2024-04-30 Govind M. Chari , Abhinav G. Kamath , Purnanand Elango , Behçet Açıkmeşe

Sampling-based motion planning methods, while effective in high-dimensional spaces, often suffer from inefficiencies due to irregular sampling distributions, leading to suboptimal exploration of the configuration space. In this paper, we…

机器人学 · 计算机科学 2025-08-28 Makram Chahine , T. Konstantin Rusch , Zach J. Patterson , Daniela Rus

Microbeam radiation therapy (MRT) utilizes coplanar synchrotron radiation beamlets and is a proposed treatment approach for several tumour diagnoses that currently have poor clinical treatment outcomes, such as gliosarcomas. Prescription…

Significance: Monte Carlo (MC) methods are the gold-standard for modeling light-tissue interactions due to their accuracy. Mesh-based MC (MMC) offers enhanced precision for complex tissue structures using tetrahedral mesh models. Despite…

分布式、并行与集群计算 · 计算机科学 2025-12-01 Shijie Yan , Douglas Dwyer , David R. Kaeli , Qianqian Fang

X-ray dose constantly gains interest in the interventional suite. With dose being generally difficult to monitor reliably, fast computational methods are desirable. A major drawback of the gold standard based on Monte Carlo (MC) methods is…

We present Generative Monte Carlo (GMC), a novel paradigm for particle transport simulation that integrates generative artificial intelligence directly into the stochastic solution of the linear Boltzmann equation. By reformulating the…

计算物理 · 物理学 2025-12-17 Joseph A. Farmer , Aidan Murray , Johannes Krotz , Ryan G. McClarren

An efficient simulation-based methodology is proposed for the rolling window estimation of state space models, called particle rolling Markov chain Monte Carlo (MCMC) with double block sampling. In our method, which is based on Sequential…

统计计算 · 统计学 2021-09-17 Naoki Awaya , Yasuhiro Omori

The answers to data assimilation questions can be expressed as path integrals over all possible state and parameter histories. We show how these path integrals can be evaluated numerically using a Markov Chain Monte Carlo method designed to…

计算物理 · 物理学 2015-05-27 John C. Quinn , Henry D. I. Abarbanel

A model to determine the dose rate of a planar alpha-emitting surface, has been developed. The approach presented is a computationally efficient mathematical model using stopping range data from the Stopping Ranges of Ions in Matter (SRIM)…

核理论 · 物理学 2021-02-05 Angus Siberry , David Hambley , Anna Adamska , Ross Springell

Purpose: To demonstrate the feasibility of fast Monte Carlo (MC) based inverse biological planning for the treatment of head and neck tumors in spot-scanning proton therapy. Methods: Recently, a fast and accurate Graphics Processor Unit…

医学物理 · 物理学 2016-10-11 H. Wan Chan Tseung , J. Ma , C. R. Kreofsky , D. Ma , C. Beltran

The next great leap toward improving treatment of cancer with radiation will require the combined use of online adaptive and magnetic resonance guided radiation therapy techniques with automatic X-ray beam orientation selection.…

医学物理 · 物理学 2019-08-14 Ryan Neph , Yangsibo Huang , Youming Yang , Ke Sheng

The present work is devoted to develop a computational model using the Gate Monte Carlo software for the simulation of a 6MV photon beam given by Elekta Synergy Platform medical linear accelerator treatment head. The model includes the…

医学物理 · 物理学 2013-09-04 Yahya Tayalati , Samir Didi , Mustafa Zerfaoui , Abdellilah Moussaa

Particle therapy relies on up-to-date knowledge of the stopping power of the patient tissues to deliver the prescribed dose distribution. The stopping power describes the average particle motion, which is encoded in the distribution of…

Online adaptive radiation therapy (ART) is an attractive concept that promises the ability to deliver an optimal treatment in response to the inter-fraction variability in patient anatomy. However, it has yet to be realized due to technical…

医学物理 · 物理学 2015-05-14 Xuejun Gu , Dongju Choi , Chunhua Men , Hubert Pan , Amitava Majumdar , Steve B. Jiang

Purpose: To investigate the validity of two Monte Carlo simulation absolute dosimetry approaches in the case of a small field dedicated `D'-shaped collimator used for the retinoblastoma treatment with external photon beam radiotherapy.…

医学物理 · 物理学 2018-09-25 P. A. Mayorga , L. Brualla , A. Flühs , W. Sauerwein , A. M. Lallena

The gamma-index dose comparison tool has been widely used to compare dose distributions in cancer radiotherapy. The accurate calculation of gamma-index requires an exhaustive search of the closest Euclidean distance in the high-resolution…

医学物理 · 物理学 2015-05-20 Xuejun Gu , Xun Jia , Steve B. Jiang

Purpose: To validate the MC-GPU Monte Carlo code for dosimetric studies in x-ray breast imaging modalities: mammography, digital breast tomosynthesis, contrast enhanced digital mammography and breast-CT. Moreover, to implement and validate…

医学物理 · 物理学 2022-04-06 Rodrigo T. Massera , Rowan M. Thomson , Alessandra Tomal

Markov Chain Monte Carlo (MCMC) methods are employed to sample from a given distribution of interest, whenever either the distribution does not exist in closed form, or, if it does, no efficient method to simulate an independent sample from…

统计计算 · 统计学 2008-07-22 Ioana A. Cosma , Masoud Asgharian

Particle Markov chain Monte Carlo (PMCMC) is a systematic way of combining the two main tools used for Monte Carlo statistical inference: sequential Monte Carlo (SMC) and Markov chain Monte Carlo (MCMC). We present a novel PMCMC algorithm…

统计计算 · 统计学 2014-09-17 Fredrik Lindsten , Michael I. Jordan , Thomas B. Schön