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Graph-based Cognitive Diagnosis (CD) has attracted much research interest due to its strong ability on inferring students' proficiency levels on knowledge concepts. While graph-based CD models have demonstrated remarkable performance, we…

计算机与社会 · 计算机科学 2025-01-23 Pengyang Shao , Yonghui Yang , Chen Gao , Lei Chen , Kun Zhang , Chenyi Zhuang , Le Wu , Yong Li , Meng Wang

Motivation: Predicting gene-disease associations (GDAs) is the problem to determine which gene is associated with a disease. GDA prediction can be framed as a ranking problem where genes are ranked for a query disease, based on features…

定量方法 · 定量生物学 2026-02-03 Fernando Zhapa-Camacho , Robert Hoehndorf

Intrinsically disordered proteins (IDPs) and multidomain proteins with flexible linkers show a high level of structural heterogeneity and are best described by ensembles consisting of multiple conformations with associated thermodynamic…

生物大分子 · 定量生物学 2021-12-13 F. Emil Thomasen , Kresten Lindorff-Larsen

Discovery gene-disease links is important in biology and medicine areas, enabling disease identification and drug repurposing. Machine learning approaches accelerate this process by leveraging biological knowledge represented in ontologies…

机器学习 · 计算机科学 2025-04-14 Catarina Canastra , Cátia Pesquita

We consider the problem of non-adaptive group testing of $N$ items out of which $K$ or less items are known to be defective. We propose a testing scheme based on left-and-right-regular sparse-graph codes and a simple iterative decoder. We…

信息论 · 计算机科学 2017-01-27 Avinash Vem , Nagaraj T. Janakiraman , Krishna R. Narayanan

Label Distribution Learning (LDL) is an effective approach for handling label ambiguity, as it can analyze all labels at once and indicate the extent to which each label describes a given sample. Most existing LDL methods consider the…

机器学习 · 计算机科学 2024-11-21 Ziqi Jia , Xiaoyang Qu , Chenghao Liu , Jianzong Wang

We study the problem of group testing with a non-adaptive randomized algorithm in the random incidence design (RID) model where each entry in the test is chosen randomly independently from $\{0,1\}$ with a fixed probability $p$. The…

机器学习 · 计算机科学 2017-08-10 Nader H. Bshouty , Nuha Diab , Shada R. Kawar , Robert J. Shahla

We consider some computationally efficient and provably correct algorithms with near-optimal sample-complexity for the problem of noisy non-adaptive group testing. Group testing involves grouping arbitrary subsets of items into pools. Each…

信息论 · 计算机科学 2016-11-18 Chun Lam Chan , Sidharth Jaggi , Venkatesh Saligrama , Samar Agnihotri

In group testing, the task is to identify defective items by testing groups of them together using as few tests as possible. We consider the setting where each item is defective with a constant probability $\alpha$, independent of all other…

离散数学 · 计算机科学 2024-11-15 Lukas Hintze , Lena Krieg , Olga Scheftelowitsch , Haodong Zhu

We formulate and analyze a stochastic threshold group testing problem motivated by biological applications. Here a set of $n$ items contains a subset of $d \ll n$ defective items. Subsets (pools) of the $n$ items are tested -- the test…

信息论 · 计算机科学 2013-04-25 Chun Lam Chan , Sheng Cai , Mayank Bakshi , Sidharth Jaggi , Venkatesh Saligrama

In the classical combinatorial (adaptive) group testing problem, one is given two integers \(d\) and \(n\), where \(0\le d\le n\), and a population of \(n\) items, exactly \(d\) of which are known to be defective. The question is to devise…

组合数学 · 数学 2014-07-24 David Cariolaro , Zhaiming Shen , Yi Zhang

Discriminating lung nodules as malignant or benign is still an underlying challenge. To address this challenge, radiologists need computer aided diagnosis (CAD) systems which can assist in learning discriminative imaging features…

计算机视觉与模式识别 · 计算机科学 2018-10-15 Maria J. M. Chuquicusma , Sarfaraz Hussein , Jeremy Burt , Ulas Bagci

Intrusion detection systems (IDSs) play an important role in identifying malicious attacks and threats in networking systems. As fundamental tools of IDSs, learning based classification methods have been widely employed. When it comes to…

密码学与安全 · 计算机科学 2019-01-29 He Zhang , Xingrui Yu , Peng Ren , Chunbo Luo , Geyong Min

The group testing problem consists of determining a sparse subset of defective items from within a larger set of items via a series of tests, where each test outcome indicates whether at least one defective item is included in the test. We…

信息论 · 计算机科学 2026-04-24 Daniel McMorrow , Jonathan Scarlett

Traditional drug design faces significant challenges due to inherent chemical and biological complexities, often resulting in high failure rates in clinical trials. Deep learning advancements, particularly generative models, offer potential…

Among the challenges that the COVID-19 pandemic outbreak revealed is the problem to reduce the number of tests required for identifying the virus carriers in order to contain the viral spread while preserving the tests reliability. To cope…

信息论 · 计算机科学 2021-12-24 Catherine A. Haddad-Zaaknoon

In group testing, simple binary-output tests are designed to identify a small number $t$ of defective items that are present in a large population of $N$ items. Each test takes as input a group of items and produces a binary output…

信息论 · 计算机科学 2017-04-11 Alexander Barg , Arya Mazumdar

The group testing problem consists of determining a small set of defective items from a larger set of items based on a number of possibly-noisy tests, and is relevant in applications such as medical testing, communication protocols, pattern…

信息论 · 计算机科学 2018-10-05 Jonathan Scarlett

Identifying disease genes from human genome is an important and fundamental problem in biomedical research. Despite many publications of machine learning methods applied to discover new disease genes, it still remains a challenge because of…

定量方法 · 定量生物学 2017-05-23 Peng Yang

Group testing enables the identification of a small subset of defective items within a larger population by performing tests on pools of items rather than on each item individually. Over the years, it has not only attracted attention from…

信息论 · 计算机科学 2026-01-13 Manuel Franco-Vivo