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The optics of any camera degrades the sharpness of photographs, which is a key visual quality criterion. This degradation is characterized by the point-spread function (PSF), which depends on the wavelengths of light and is variable across…

图像与视频处理 · 电气工程与系统科学 2022-08-02 Thomas Eboli , Jean-Michel Morel , Gabriele Facciolo

We report the implementation of a fully on-chip, lensless microscopy technique termed optofluidic ptychography. This imaging modality complements the miniaturization provided by microfluidics and allows the integration of ptychographic…

仪器与探测器 · 物理学 2021-12-21 Pengming Song , Chengfei Guo , Shaowei Jiang , Tianbo Wang , Patrick Hu , Derek Hu , Zibang Zhang , Bin Feng , Guoan Zheng

Adaptive optics (AO) has revolutionized imaging in {fields} from astronomy to microscopy by correcting optical aberrations. In label-free microscopes, however, conventional AO faces limitations due to the absence of guidestar and the need…

Dispersion engineering is a long-standing challenge in optical systems, and it is particularly important for metasurfaces, which naturally suffer from strong chromatic aberrations due to their ultralow profile. Stacks of metasurfaces have…

应用物理 · 物理学 2025-04-04 Yuzhong Wang , Axiang Yu , Yayun Cheng , Yongkang Dong , Jiaran Qi , Andrea Alu

Optical detection of nanoscale objects without relying on fluorescence is a current challenge due to their extremely weak interaction with light. Resonator-enhanced absorption microscopy is a novel tool to heavily boost the light-matter…

Adaptive optics (AO) are reconfigurable devices that compensate for wavefront distortions or aberrations in optical systems such as microscopes, telescopes and ophthalmoscopes. Aberrations have detrimental effects that can reduce imaging…

光学 · 物理学 2025-06-10 Biwei Zhang , Martin J. Booth , Qi Hu

To overcome the limit of diffraction while achieving the superresolution technique, solid immersion lenses are the key optical elements for data storage and nanophotonics applications. Recent demonstrations have shown how different…

光学 · 物理学 2026-02-24 Subhankar Roy , Jianping Hu , M Ummal Momeen

In recent years several methods to overcome diffraction limit in the far field microscopy have been demonstrated. Still the problem of superresolution is reliably solved only for fluorescent microscopy, giving a resolution of up to 20-30nm.…

光学 · 物理学 2013-09-03 Yu. V. Miklyaev , S. A. Asselborn , K. A. Zaytsev , M. Ya. Darscht

Linear super-resolution microscopy via synthesis aperture approach permits fast acquisition because of its wide-field implementations, however, it has been limited in resolution because a missing spatial-frequency band occurs when trying to…

The numerical aperture (NA) of a lens determines its ability to focus light and its resolving capability. Having a large NA is a very desirable quality for applications requiring small light-matter interaction volumes or large angular…

Chip-based Evanescent Light Scattering (cELS) utilizes the multiple modes of a high-index contrast optical waveguide for near-field illumination of unlabeled samples, thereby repositioning the highest spatial frequencies of the sample into…

Machine learning methods for computational imaging require uncertainty estimation to be reliable in real settings. While Bayesian models offer a computationally tractable way of recovering uncertainty, they need large data volumes to be…

机器学习 · 计算机科学 2020-08-24 Francesco Tonolini , Jack Radford , Alex Turpin , Daniele Faccio , Roderick Murray-Smith

Scanning X-ray nanodiffraction microscopy is a powerful technique for spatially resolving nanoscale structural morphologies by diffraction contrast. One of the critical challenges in experimental nanodiffraction data analysis is posed by…

应用物理 · 物理学 2024-06-26 Aileen Luo , Tao Zhou , Martin V. Holt , Andrej Singer , Mathew J. Cherukara

Fourier ptychographic microscopy is a computational imaging technique that provides quantitative phase information and high resolution over a large field-of-view. Although the technique presents numerous advantages over conventional…

光学 · 物理学 2021-09-16 Eric Li , Stuart Sherwin , Gautam Gunjala , Laura Waller

We present a reference-free computational wavefront sensor based on binary amplitude modulation and phase retrieval. The method employs Digital Micro-mirror Device as a programmable amplitude modulator and reconstructs the complex optical…

光学 · 物理学 2026-02-12 Ondrej Denk , Jan Pilar , Martin Divoky , Miroslav Cech , Tomas Mocek

We present a novel, general-purpose method for deconvolving and denoising images from gridded radio interferometric visibilities using Bayesian inference based on a Gaussian process model. The method automatically takes into account…

Light sheet fluorescence microscopy (LSFM) has transformed the way we visualize biological tissues in three dimensions, offering high-resolution imaging while minimizing photo-induced damage to the samples. Recent breakthroughs in…

光学 · 物理学 2025-05-27 Alireza Tabatabaei Mashayekh , Jeremy Witzens

Purpose: To develop a deep learning-based Bayesian inference for MRI reconstruction. Methods: We modeled the MRI reconstruction problem with Bayes's theorem, following the recently proposed PixelCNN++ method. The image reconstruction from…

计算机视觉与模式识别 · 计算机科学 2022-02-18 GuanXiong Luo , Na Zhao , Wenhao Jiang , Edward S. Hui , Peng Cao

Image restoration of biological structures in microscopy poses unique challenges for preserving fine textures and sharp edges. While recent GAN-based image restoration formulations have introduced frequency-domain losses for natural images,…

定量方法 · 定量生物学 2026-01-30 Xingjian Zhang , Claire Leclech , Louison Blivet-Bailly , Abdul I. Barakat , Elsa D. Angelini

Integration of metasurfaces with guided mode sources like waveguides have opened new frontiers for on-chip optical integration. However, the state-of-the-art in the field has targeted applications where long focal distances over thousands…

光学 · 物理学 2024-03-05 Hrishikesh Iyer , Yurii Vlasov