相关论文: Solitary electromechanical pulses in Lobster neuro…
The action potential is widely considered a purely electrical phenomenon. However, one also finds mechanical and thermal changes that can be observed experimentally. In particular, nerve membranes become thicker and axons contract. The…
It has long been known that there is no measurable heat production associated with the nerve pulse. Rather, one finds that heat production is biphasic, and a heat release during the first phase of the action potential is followed by the…
Comprehending the nature of action potentials is fundamental to our understanding of the functioning of nervous systems in general. Here we consider their evolution and describe their functions of communication, modulation and computation…
The textbook picture of nerve activity is that of a propagating voltage pulse driven by electrical currents through ion channel proteins, which are gated by changes in voltage, temperature, pressure or by drugs. All function is directly…
The collisions of two simultaneously generated impulses in the giant axons of both earthworms and lobster propagating in orthodromic and antidromic direction were investigated. The experiments have been performed on the extracted ventral…
Nerves are frequently stretched during movement. We investigate here the effect of stretch on nerve excitability within the framework of the soliton theory. This thermodynamic theory for nerve pulse propagation relies on the presence of a…
We study a stochastic process describing the continuous time evolution of the membrane potentials of finite system of neurons in the absence of external stimuli. The values of the membrane potentials evolve under the effect of {\it chemical…
An action potential is typically described as a purely electrical change that propagates along the membrane of excitable cells. However, recent experiments have demonstrated that non-linear acoustic pulses that propagate along lipid…
In a succession of articles published over 65 years ago, Sir Alan Lloyd Hodgkin and Sir Andrew Fielding Huxley established what now forms our physical understanding of excitation in nerve, and how the axon conducts the action potential.…
Weakly electric fish are unique models in Neuroscience allowing experimentalists to access, with non invasive techniques,a central nervous system generated spatio-temporal electric pattern of pulses with roles in at least two complex and…
In this paper mathematical models are formulated in order to simulate heat production and corresponding temperature changes which accompany the propagation of an axon potential. Based on earlier experimental results, several models are…
Detailed knowledge of mechanical parameters such as cell elasticity, stiffness of the growth substrate, or traction stresses generated during axonal extensions is essential for understanding the mechanisms that control neuronal growth. Here…
Stimulated by ongoing discussions about the relevance of mechanical motion in the propagation of nerve signals capillary waves of water-based electrolytes in elastic tubular systems are considered as an essential ingredient. Their…
In an ongoing debate on the physical nature of the action potential, one group adheres to the electrical model of Hodgkin and Huxley, while the other describes the action potential as a non-linear acoustic pulse propagating within an…
We present a recent theory for nerve pulse propagation and anesthesia and argue that both nerve activity and the action of anesthetics can be understood on the basis of simple physical laws. It was found experimentally that biological…
We investigate different mechanical effects which accompany the nerve pulse propagation by using mathematical modeling. The propagation process is composed by three connected phenomena: (i) the action potential (electrical signal) which is…
Using a simple model, we study the fluctuating dynamics of inextensible, semiflexible polar filaments interacting with active and directed force generating centres such as molecular motors. Taking into account the fact that the activity…
The Hodgkin-Huxley model of nerve pulse propagation relies on ion currents through specific resistors called ion channels. We discuss a number of classical thermodynamic findings on nerves that are not contained in this classical theory.…
We consider the thermodynamic behavior of a disordered interacting electron system in two dimensions. We show that the corrections to the thermodynamic potential in the weakly localized regime give rise to a non monotonic behavior of the…
In the recent years we have shown that cylindrical biological membranes such as nerve axons under physiological conditions are able to support stable electromechanical pulses called solitons. These pulses share many similarities with the…