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The biomedical field relies heavily on concept linking in various areas such as literature mining, graph alignment, information retrieval, question-answering, data, and knowledge integration. Although large language models (LLMs) have made…

计算与语言 · 计算机科学 2023-07-04 Qinyong Wang , Zhenxiang Gao , Rong Xu

Relationships in scientific data, such as the numerical and spatial distribution relations of features in univariate data, the scalar-value combinations' relations in multivariate data, and the association of volumes in time-varying and…

机器学习 · 计算机科学 2022-07-25 Xiangyang He , Yubo Tao , Shuoliu Yang , Haoran Dai , Hai Lin

With the exponential growth of the life science literature, biomedical text mining (BTM) has become an essential technology for accelerating the extraction of insights from publications. Identifying named entities (e.g., diseases, drugs, or…

计算与语言 · 计算机科学 2024-10-15 Mario Sänger , Samuele Garda , Xing David Wang , Leon Weber-Genzel , Pia Droop , Benedikt Fuchs , Alan Akbik , Ulf Leser

Objective: We aim to learn potential novel cures for diseases from unstructured text sources. More specifically, we seek to extract drug-disease pairs of potential cures to diseases by a simple reasoning over the structure of spoken text.…

Uncontextualized word embeddings are reliable feature representations of words used to obtain high quality results for various NLP applications. Given the historical success of word embeddings in NLP, we propose a retrospective on some of…

计算与语言 · 计算机科学 2019-12-02 Edward Newell , Kian Kenyon-Dean , Jackie Chi Kit Cheung

Entity recognition is a critical first step to a number of clinical NLP applications, such as entity linking and relation extraction. We present the first attempt to apply state-of-the-art entity recognition approaches on a newly released…

计算与语言 · 计算机科学 2019-10-04 Kathleen C. Fraser , Isar Nejadgholi , Berry De Bruijn , Muqun Li , Astha LaPlante , Khaldoun Zine El Abidine

Repurposing existing drugs to treat new diseases is a cost-effective alternative to de novo drug development, but there are millions of potential drug-disease combinations to be considered with only a small fraction being viable. In silico…

定量方法 · 定量生物学 2025-10-24 Austin Polanco , M. E. J. Newman

Protein-ligand interactions are one of the fundamental types of molecular interactions in living systems. Ligands are small molecules that interact with protein molecules at specific regions on their surfaces called binding sites. Tasks…

生物大分子 · 定量生物学 2020-08-11 Arnab Bhadra , Kalidas Y

Researchers and practitioners in natural language processing and computational linguistics frequently observe and analyze the real language usage in large-scale corpora. For that purpose, they often employ off-the-shelf pattern-matching…

计算与语言 · 计算机科学 2025-03-06 Hiroyuki Deguchi , Go Kamoda , Yusuke Matsushita , Chihiro Taguchi , Kohei Suenaga , Masaki Waga , Sho Yokoi

Objective: Clinical trials are essential for advancing pharmaceutical interventions, but they face a bottleneck in selecting eligible participants. Although leveraging electronic health records (EHR) for recruitment has gained popularity,…

计算与语言 · 计算机科学 2026-01-15 Mojdeh Rahmanian , Seyed Mostafa Fakhrahmad , Seyedeh Zahra Mousavi

Topic modeling is used for discovering latent semantic structure, usually referred to as topics, in a large collection of documents. The most widely used methods are Latent Dirichlet Allocation and Probabilistic Latent Semantic Analysis.…

计算与语言 · 计算机科学 2020-08-24 Dimo Angelov

The advent of Large Language Models (LLMs) is promising and LLMs have been applied to numerous fields. However, it is not trivial to implement LLMs in the medical field, due to the high standards for precision and accuracy. Currently, the…

信息检索 · 计算机科学 2024-12-04 Rishabh Goel

In this work, we examine the extent to which embeddings may encode marginalized populations differently, and how this may lead to a perpetuation of biases and worsened performance on clinical tasks. We pretrain deep embedding models (BERT)…

计算与语言 · 计算机科学 2020-03-26 Haoran Zhang , Amy X. Lu , Mohamed Abdalla , Matthew McDermott , Marzyeh Ghassemi

Analyzing the writing styles of authors and articles is a key to supporting various literary analyses such as author attribution and genre detection. Over the years, rich sets of features that include stylometry, bag-of-words, n-grams have…

信息检索 · 计算机科学 2023-10-27 Nafis Irtiza Tripto , Mohammed Eunus Ali

A fundamental goal of search engines is to identify, given a query, documents that have relevant text. This is intrinsically difficult because the query and the document may use different vocabulary, or the document may contain query words…

信息检索 · 计算机科学 2016-02-04 Bhaskar Mitra , Eric Nalisnick , Nick Craswell , Rich Caruana

Semantic concepts and relations encoded in domain-specific ontologies and other medical semantic resources play a crucial role in deciphering terms in medical queries and documents. The exploitation of these resources for tackling the…

信息检索 · 计算机科学 2020-05-19 Mohammed Maree , Israa Noor , Khaled Rabayah , Mohammed Belkhatir , Saadat M. Alhashmi

Clinical trials are central to medical progress because they help improve understanding of human health and the healthcare system. They play a key role in discovering new ways to detect, prevent, or treat diseases, and it is essential that…

计算与语言 · 计算机科学 2025-10-16 Surya Tejaswi Yerramsetty , Almas Fathimah

The COVID-19 pandemic has put immense pressure on health systems which are further strained due to the misinformation surrounding it. Under such a situation, providing the right information at the right time is crucial. There is a growing…

计算与语言 · 计算机科学 2020-11-02 Ridam Pal , Rohan Pandey , Vaibhav Gautam , Kanav Bhagat , Tavpritesh Sethi

The development of state-of-the-art (SOTA) Natural Language Processing (NLP) systems has steadily been establishing new techniques to absorb the statistics of linguistic data. These techniques often trace well-known constructs from…

计算与语言 · 计算机科学 2022-05-03 Jake Ryland Williams , Hunter Scott Heidenreich

Dementia is a progressive neurological disorder that profoundly affects the daily lives of older adults, impairing abilities such as verbal communication and cognitive function. Early diagnosis is essential for enhancing both lifespan and…

计算工程、金融与科学 · 计算机科学 2023-11-07 Kaiying Lin , Peter Washington