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A topic of intense current investigation pursues the question how the highly crowded environment of biological cells affects the dynamic properties of passively diffusing particles. Motivated by recent experiments we report results of…

统计力学 · 物理学 2016-09-28 Surya K. Ghosh , Andrey G. Cherstvy , Denis S. Grebenkov , Ralf Metzler

Macromolecular diffusion in strongly confined geometries and crowded environments is still to a large extent an open subject in soft matter physics and biology. In this paper, we employ large-scale Langevin dynamics simulations to…

软凝聚态物质 · 物理学 2020-10-07 T. P. O. Nogueira , H. O. Frota , Francesco Piazza , José Rafael Bordin

We study a two-dimensional diffusive motion of a tracer particle in restricted, crowded anisotropic geometries. The underlying medium is the same as in our previous work [J. Chem. Phys. 140, 044706 (2014)] in which standard, gaussian…

化学物理 · 物理学 2020-03-17 Michał Cieśla , Bartłomiej Dybiec , Ewa Gudowska-Nowak , Igor Sokolov

We use molecular dynamics simulations to investigate the tracer diffusion in a sea of polymers with specific binding zones for the tracer. These binding zones act as traps. Our simulations show that the tracer can undergo normal yet…

软凝聚态物质 · 物理学 2016-09-22 Nairhita Samanta , Rajarshi Chakrabarti

Crowded environments modify the diffusion of macromolecules, generally slowing their movement and inducing transient anomalous subdiffusion. The presence of obstacles also modifies the kinetics and equilibrium behavior of tracers. While…

We summarise different results on the diffusion of a tracer particle in lattice gases of hard-core particles with stochastic dynamics, which are confined to narrow channels -- single-files, comb-like structures and quasi-one-dimensional…

统计力学 · 物理学 2018-11-14 O. Benichou , P. Illien , G. Oshanin , A. Sarracino , R. Voituriez

We study the diffusion of a tracer particle driven out-of-equilibrium by an external force and traveling in a dense environment of arbitrary density. The system evolves on a discrete lattice and its stochastic dynamics is described by a…

We investigate the obstructed motion of tracer (test) particles in crowded environments by carrying simulations of two-dimensional Gaussian random walk in model fibrinogen monolayers of different orientational ordering. The fibrinogen…

化学物理 · 物理学 2014-03-14 Michał Cieśla , Ewa Gudowska-Nowak , Francesc Sagués , Igor M. Sokolov

We study by extensive numerical simulations the dynamics of a hard-core tracer particle (TP) in presence of two competing types of disorder - frozen convection flows on a square random Manhattan lattice and a crowded dynamical environment…

无序系统与神经网络 · 物理学 2020-06-24 Carlos Mejía-Monasterio , Sergei Nechaev , Gleb Oshanin , Oleg Vasilyev

Gradient-driven diffusion in crowded, multicomponent mixtures is a topic of high interest because of its role in biological processes such as transport in cell membranes. In partially phase-separated solutions, gradient-driven diffusion…

软凝聚态物质 · 物理学 2017-02-15 Prithviraj Nandigrami , Brandy Grove , Andrew Konya , Robin L. B. Selinger

We study analytically the dynamics and the micro-structural changes of a host medium caused by a driven tracer particle moving in a confined, quiescent molecular crowding environment. Imitating typical settings of active micro-rheology…

统计力学 · 物理学 2016-03-17 O. Bénichou , P. Illien , G. Oshanin , A. Sarracino , R. Voituriez

Based on a coarse-grained model, we carry out molecular dynamics simulations to analyze the diffusion of a small tracer particle inside a cylindrical channel whose inner wall is covered with randomly grafted short polymeric chains. We…

软凝聚态物质 · 物理学 2013-06-20 Rajarshi Chakrabarti , Stefan Kesselheim , Peter Kosovan , Christian Holm

The diffusion of a particle in a crowded environment typically proceeds through three regimes: for very short times the particle diffuses freely until it collides with an obstacle for the first time, while for very long times diffusion the…

生物物理 · 物理学 2019-10-09 Nguiya P. Neo , Gary W. Slater

We calculate the diffusion coefficient of an active tracer in a schematic crowded environment, represented as a lattice gas of passive particles with hardcore interactions. Starting from the master equation of the problem, we put forward a…

统计力学 · 物理学 2022-02-02 Pierre Rizkallah , Alessandro Sarracino , Olivier Bénichou , Pierre Illien

Tracer diffusion in crowded environments is central to many biological and soft matter systems, but quantitative frameworks for linking tracer motion to environmental structure remain limited. Here, we study the transport of rigid tracers…

软凝聚态物质 · 物理学 2026-05-07 Jinseok Lee , Tong Lin , Mengyang Gu , Yimin Luo

The paper addresses the single-file diffusion in the presence of an absorbing boundary. The emphasis is on an interplay between the hard-core interparticle interaction and the absorption process. The resulting dynamics exhibits several…

统计力学 · 物理学 2014-02-26 Artem Ryabov , Petr Chvosta

We present a framework for systems in which diffusion-advection transport of a tracer substance in a mobile zone is interrupted by trapping in an immobile zone. Our model unifies different model approaches based on distributed-order…

统计力学 · 物理学 2022-04-05 T. J. Doerries , A. V. Chechkin , R. Schumer , R. Metzler

We investigate the dynamics of a single tracer exploring a course of fixed obstacles in the vicinity of the percolation transition for particles confined to the infinite cluster. The mean-square displacement displays anomalous transport,…

统计力学 · 物理学 2015-03-17 Markus Spanner , Felix Höfling , Gerd Schröder-Turk , Klaus Mecke , Thomas Franosch

Living systems at the sub-cellular, cellular, and multi-cellular level are often crowded systems that contain active particles. The active motion of these particles can also propel passive particles, which typically results in enhanced…

软凝聚态物质 · 物理学 2021-05-12 Leila Abbaspour , Stefan Klumpp

The dynamics of a tracer particle in a glassy matrix of obstacles displays slow complex transport as the free volume approaches a critical value and the void space falls apart. We investigate the emerging subdiffusive motion of the test…

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