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Popular software packages report four generalizations of the ANOVA F test when conducting a multivariate analysis of variance (MANOVA). The reported operating characteristics of these fours tests vary widely depending on which research…

统计计算 · 统计学 2026-04-22 Joseph D Consiglio

The problem of multiple hypothesis testing arises when there are more than one hypothesis to be tested simultaneously for statistical significance. This is a very common situation in many data mining applications. For instance, assessing…

机器学习 · 统计学 2009-06-30 Sami Hanhijärvi , Kai Puolamäki , Gemma C. Garriga

Analysis of variance (ANOVA) reveals some disadvantages, such as non-robustness against heteroscedastic or non-normal errors and using difference to overall mean as effect sizes only. As an alternative the multiple contrast test comparing…

统计方法学 · 统计学 2023-03-27 Ludwig A. Hothorn

Statistical tests that compare classification algorithms are univariate and use a single performance measure, e.g., misclassification error, $F$ measure, AUC, and so on. In multivariate tests, comparison is done using multiple measures…

机器学习 · 统计学 2014-09-17 Olcay Taner Yildiz , Ethem Alpaydin

Standard ANOVA is among the most widely used tests in the life sciences and beyond. Several alternatives are proposed to provide simultaneous confidence intervals, ensure tight control of FWER, be robust to variance heterogeneity, avoid…

统计方法学 · 统计学 2022-06-01 Ludwig A. Hothorn

It is quite common in modern research, for a researcher to test many hypotheses. The statistical (frequentist) hypothesis testing framework, does not scale with the number of hypotheses in the sense that naively performing many hypothesis…

统计方法学 · 统计学 2013-06-26 Jonathan Rosenblatt

We consider clinical trials with multiple, overlapping patient populations, that test multiple treatment policies specifically tailored to these populations. Such designs may lead to multiplicity issues, as false statements will affect…

统计方法学 · 统计学 2025-11-13 Remi Luschei , Werner Brannath

Consider the problem of simultaneously testing null hypotheses H_1,...,H_s. The usual approach to dealing with the multiplicity problem is to restrict attention to procedures that control the familywise error rate (FWER), the probability of…

统计理论 · 数学 2007-06-13 E. L. Lehmann , Joseph P. Romano

During multiple testing, researchers often adjust their alpha level to control the familywise error rate for a statistical inference about a joint union alternative hypothesis (e.g., "H1,1 or H1,2"). However, in some cases, they do not make…

统计方法学 · 统计学 2024-04-04 Mark Rubin

Multiple testing problems are a staple of modern statistical analysis. The fundamental objective of multiple testing procedures is to reject as many false null hypotheses as possible (that is, maximize some notion of power), subject to…

统计方法学 · 统计学 2020-11-30 Saharon Rosset , Ruth Heller , Amichai Painsky , Ehud Aharoni

When comparing multiple groups in clinical trials, we are not only interested in whether there is a difference between any groups but rather the location. Such research questions lead to testing multiple individual hypotheses. To control…

统计方法学 · 统计学 2025-01-08 Ina Dormuth , Carolin Herrmann , Frank Konietschke , Markus Pauly , Matthias Wirth , Marc Ditzhaus

Testing for the significance of a subset of regression coefficients in a linear model, a staple of statistical analysis, goes back at least to the work of Fisher who introduced the analysis of variance (ANOVA). We study this problem under…

统计理论 · 数学 2012-02-24 Ery Arias-Castro , Emmanuel J. Candès , Yaniv Plan

Large-scale multiple testing is a fundamental problem in high dimensional statistical inference. It is increasingly common that various types of auxiliary information, reflecting the structural relationship among the hypotheses, are…

统计方法学 · 统计学 2021-10-07 Hongyuan Cao , Jun Chen , Xianyang Zhang

We study the problem of multiple hypothesis testing for multidimensional data when inter-correlations are present. The problem of multiple comparisons is common in many applications. When the data is multivariate and correlated, existing…

统计理论 · 数学 2015-06-02 Mahdis Azadbakhsh , Xin Gao , Hanna Jankowski

Factorial experiments in research on memory, language, and in other areas are often analyzed using analysis of variance (ANOVA). However, for effects with more than one numerator degrees of freedom, e.g., for experimental factors with more…

统计方法学 · 统计学 2019-07-19 Daniel J. Schad , Shravan Vasishth , Sven Hohenstein , Reinhold Kliegl

After rejecting the null hypothesis in the analysis of variance, the next step is to make the pairwise comparisons to find out differences in means. The purpose of this paper is threefold. The foremost aim is to suggest expression for…

统计方法学 · 统计学 2023-06-22 Elsayed A. H. Elamir

The field of psychological sciences has been grappling with the replicability crisis. Various issues have been identified as potential sources of this problem. We bring to light a potential source that has largely been overlooked and…

统计方法学 · 统计学 2025-04-28 Yoav Zeevi , Sofi Astashenko , Liad Mudrik , Yoav Benjamini

Modern machine learning methods are often overparametrized, allowing adaptation to the data at a fine level. This can seem puzzling; in the worst case, such models do not need to generalize. This puzzle inspired a great amount of work,…

机器学习 · 统计学 2021-06-10 Licong Lin , Edgar Dobriban

We consider large-scale studies in which thousands of significance tests are performed simultaneously. In some of these studies, the multiple testing procedure can be severely biased by latent confounding factors such as batch effects and…

统计方法学 · 统计学 2016-06-21 Jingshu Wang , Qingyuan Zhao , Trevor Hastie , Art B. Owen

When many (m) null hypotheses are tested with a single dataset, the control of the number of false rejections is often the principal consideration. Two popular controlling rates are the probability of making at least one false discovery…

统计方法学 · 统计学 2013-07-11 Djalel Eddine Meskaldji , Jean-Philippe Thiran , Stephan Morgenthaler
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