相关论文: How important is the seizure onset zone for seizur…
Objective: This work investigates the hypothesis that focal seizures can be predicted using scalp electroencephalogram (EEG) data. Our first aim is to learn features that distinguish between the interictal and preictal regions. The second…
The study of dynamical systems defined on complex networks provides a natural framework with which to investigate myriad features of neural dynamics, and has been widely undertaken. Typically, however, networks employed in theoretical…
Over one third of the estimated 3 million people with epilepsy in the US are medication resistant. Responsive neurostimulation from chronically implanted electrodes provides a promising treatment option and alternative to resective surgery.…
Early management and better clinical outcomes for epileptic patients depend on seizure prediction. The accuracy and false alarm rates of existing systems are often compromised by their dependence on static thresholds and basic…
Epilepsy is one of the most common neurological disorders globally, affecting millions of individuals. Despite significant advancements, the precise mechanisms underlying this condition remain largely unknown, making accurately predicting…
While Deep Learning (DL) is often considered the state-of-the art for Artificial Intelligence-based medical decision support, it remains sparsely implemented in clinical practice and poorly trusted by clinicians due to insufficient…
Epilepsy is known to drastically alter brain dynamics during seizures (ictal periods), but its effects on background (non-ictal) brain dynamics remain poorly understood. To investigate this, we analyzed an in-house dataset of brain activity…
Diagnosing epilepsy requires accurate seizure detection and classification, but traditional manual EEG signal analysis is resource-intensive. Meanwhile, automated algorithms often overlook EEG's geometric and semantic properties critical…
Diagnosing seizure onset zone (SOZ) is a challenge in neurosurgery, where stereoelectroencephalography (sEEG) serves as a critical technique. In sEEG SOZ identification, the existing studies focus solely on the intra-patient representation…
Pathological hubs in the brain networks of epilepsy patients are hypothesized to drive seizure generation and propagation. In epilepsy-surgery patients, these hubs have traditionally been associated with the resection area (RA): the region…
Epilepsy is one of the most prevalent neurological conditions, where an epileptic seizure is a transient occurrence due to abnormal, excessive and synchronous activity in the brain. Electroencephalogram signals emanating from the brain may…
Predicting seizure freedom is essential for tailoring epilepsy treatment. But accurate prediction remains challenging with traditional methods, especially with diverse patient populations. This study developed a deep learning-based graph…
Epileptic biomarkers play a crucial role in identifying the origin of seizures, an essential aspect of pre-surgical planning for epilepsy treatment. These biomarkers can vary significantly over time. By studying these temporal fluctuations,…
In these companion papers, we study how the interrelated dynamics of sodium and potassium affect the excitability of neurons, the occurrence of seizures, and the stability of persistent states of activity. In this first paper, we construct…
Network theory provides novel concepts that promise an improved characterization of interacting dynamical systems. Within this framework, evolving networks can be considered as being composed of nodes, representing systems, and of…
Electroencephalogram (EEG) is a prominent way to measure the brain activity for studying epilepsy, thereby helping in predicting seizures. Seizure prediction is an active research area with many deep learning based approaches dominating the…
Epileptic seizure detection and classification in clinical electroencephalogram data still is a challenge, and only low sensitivity with a high rate of false positives has been achieved with commercially available seizure detection tools,…
Automatic classification of epileptic seizure types in electroencephalograms (EEGs) data can enable more precise diagnosis and efficient management of the disease. This task is challenging due to factors such as low signal-to-noise ratios,…
Epilepsy is one of the most occurring neurological diseases. The main characteristic of this disease is a frequent seizure, which is an electrical imbalance in the brain. It is generally accompanied by shaking of body parts and even leads…
Epileptic seizures are neurological disorders characterized by abnormal and excessive electrical activity in the brain, resulting in recurrent seizure events. Electroencephalogram (EEG) signals are widely used for seizure diagnosis due to…