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Primates display a marked ability to learn habits in uncertain and dynamic environments. The associated perceptions and actions of such habits engage distributed neural circuits. Yet, precisely how such circuits support the computations…

神经元与认知 · 定量生物学 2020-06-26 Karol P. Szymula , Fabio Pasqualetti , Ann M. Graybiel , Theresa M. Desrochers , Danielle S. Bassett

We investigate scaling properties of human brain functional networks in the resting-state. Analyzing network degree distributions, we statistically test whether their tails scale as power-law or not. Initial studies, based on least-squares…

神经元与认知 · 定量生物学 2017-02-03 Riccardo Zucca , Xerxes D. Arsiwalla , Hoang Le , Mikail Rubinov , Paul Verschure

Abnormal cortical folding patterns may be related to neurodevelopmental disorders such as lissencephaly and polymicrogyria. In this context, computational modeling is a powerful tool to provide a better understanding of the early brain…

The quintessential property of neuronal systems is their intensive patterns of selective synaptic connections. The current work describes a physics-based approach to neuronal shape modeling and synthesis and its consideration for the…

神经元与认知 · 定量生物学 2009-11-10 Luciano da Fontoura Costa , Regina Celia Coelho

The wiring diagram of the mouse brain has recently been mapped at a mesoscopic scale in the Allen Mouse Brain Connectivity Atlas. Axonal projections from brain regions were traced using green fluoresent proteins. The resulting data were…

神经元与认知 · 定量生物学 2018-12-24 Pascal Grange

We study coagulation-fragmentation equations inspired by a simple model proposed in fisheries science to explain data for the size distribution of schools of pelagic fish. Although the equations lack detailed balance and admit no…

偏微分方程分析 · 数学 2016-11-03 Pierre Degond , Jian-Guo Liu , Robert L. Pego

Does the relationship between learning rules and brain alignment generalize across species? We extend our prior finding that untrained CNNs match backpropagation at human V1 by testing the same five learning rules against macaque…

机器学习 · 计算机科学 2026-05-22 Nils Leutenegger

Many popular random partition models, such as the Chinese restaurant process and its two-parameter extension, fall in the class of exchangeable random partitions, and have found wide applicability in model-based clustering, population…

统计方法学 · 统计学 2017-11-21 Giuseppe Di Benedetto , François Caron , Yee Whye Teh

Data-driven brain parcellations aim to provide a more accurate representation of an individual's functional connectivity, since they are able to capture individual variability that arises due to development or disease. This renders…

神经元与认知 · 定量生物学 2017-03-30 Sofia Ira Ktena , Salim Arslan , Sarah Parisot , Daniel Rueckert

The semicircular canals of the inner ear are involved in balance and velocity control. Being crucial to ensure efficient mobility, their morphology exhibits an evolutionary conservatism attributed to stabilizing selection. Release of…

Living organisms survive and multiply even though they have uncertain and incomplete information about their environment and imperfect models to predict the consequences of their actions. Bayesian models have been proposed to face this…

新兴技术 · 计算机科学 2015-11-13 Jacques Droulez , David Colliaux , Audrey Houillon , Pierre Bessière

Despite differences in brain sizes and cognitive niches among mammals, their cerebral cortices posses many common features and regularities. These regularities have been a subject of experimental investigation in neuroanatomy for the last…

神经元与认知 · 定量生物学 2007-05-23 Jan Karbowski

We model the growth of a cell population using a piecewise deterministic Markov branching tree. In this model, each cell splits into two offspring at a division rate $B(x)$, which depends on its size $x$. The size of each cell increases…

概率论 · 数学 2024-09-06 Nathalie Krell

The human connectome has been widely studied over the past decade. A principal finding is that it can be decomposed into communities of densely interconnected brain regions. This result, however, may be limited methodologically. Past…

The three-dimensional data-driven Allen Gene Expression Atlas of the adult mouse brain consists of numerized in-situ hybridization data for thousands of genes, co-registered to the Allen Reference Atlas. We propose quantitative criteria to…

定量方法 · 定量生物学 2012-05-15 Pascal Grange , Partha P. Mitra

Protein distributions measured under a broad set of conditions in bacteria and yeast were shown to exhibit a common skewed shape, with variances depending quadratically on means. For bacteria these properties were reproduced by temporal…

生物物理 · 物理学 2015-10-28 Naama Brenner , C. M. Newman , Dino Osmanovic , Yitzhak Rabin , Hanna Salman , D. L. Stein

White matter in mammal brains forms a densely interconnected communication network. Due to high edge density, along with continuous generation and spread of messages, brain networks must contend with congestion, which may limit polysynaptic…

神经元与认知 · 定量生物学 2025-05-22 Yan Hao , Tate Tower , Hannah Lax , Marc-Thorsten Hütt , Daniel J. Graham

Brain morphology is shaped by genetic and mechanical factors and is linked to biological development and diseases. Its fractal-like features, regional anisotropy, and complex curvature distributions hinder quantitative insights in medical…

神经元与认知 · 定量生物学 2025-09-09 Yingjie Zhao , Yicheng Song , Fan Xu , Zhiping Xu

Brain can be represented as a network, where regions are the nodes and relations between the regions are edges. Within a network, co-existence of cooperative and competitive relationships between different nodes is called coopetition.…

神经元与认知 · 定量生物学 2018-02-13 Subhadip Paul , Satyam Mukherjee , Sagnik Bhattacharyya

A basal animal model is described as an organism similar to a Limpet that is attached to the sea floor living in a reproductive community. Its brain model uses logic cells (gates) to create a high frequency spike generator. Addition logic…

其他定量生物学 · 定量生物学 2016-12-19 Robert Alan Brown