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In a recent paper we presented a simple two compartment model which describes the influence of inhaled concentrations on exhaled breath concentrations for volatile organic compounds (VOCs) with small Henry constants. In this paper we extend…

Isothermal rebreathing has been proposed as an experimental technique for estimating the alveolar levels of hydrophilic volatile organic compounds (VOCs) in exhaled breath. Using the prototypic test compound acetone we demonstrate that the…

Isoprene is one of the most abundant endogenous volatile organic compounds (VOCs) contained in human breath and is considered to be a potentially useful biomarker for diagnostic and monitoring purposes. However, neither the exact…

Human breath contains a myriad of endogenous volatile organic compounds (VOCs) which are reflective of ongoing metabolic or physiological processes. While research into the diagnostic potential and general medical relevance of these trace…

Recommended standardized procedures for determining exhaled lower respiratory nitric oxide and nasal nitric oxide have been developed by task forces of the European Respiratory Society and the American Thoracic Society. These…

定量方法 · 定量生物学 2015-03-13 Julian King , Karl Unterkofler , Gerald Teschl , Susanne Teschl , Helin Koc , Hartmann Hinterhuber , Anton Amann

Diabetes is a global health burden, and early detection is critical for timely intervention. This study explores a non-invasive, data-driven framework to identify individuals at risk of diabetes using Volatile Organic Compounds (VOCs) and…

机器学习 · 计算机科学 2026-05-22 Varsha Sharma , Prasanta K. Guha , Avik Ghose

A real-time recording setup combining exhaled breath VOC measurements by proton transfer reaction mass spectrometry (PTR-MS) with hemodynamic and respiratory data is presented. Continuous automatic sampling of exhaled breath is implemented…

定量方法 · 定量生物学 2009-07-20 J. King , A. Kupferthaler , K. Unterkofler , H. Koc , S. Teschl , G. Teschl , W. Miekisch , J. Schubert , H. Hinterhuber , A. Amann

Volatile organic compounds (VOCs) in human breath can reveal a large spectrum of health conditions and can be used for fast, accurate and non-invasive diagnostics. Gas chromatography-mass spectrometry (GC-MS) is used to measure VOCs, but…

In this paper we present a method for the estimation of leaks in non-invasive ventilation. Accurate estimation of leaks is a key component of a ventilator, since it determines the ventilator performance in terms of patient-ventilator…

医学物理 · 物理学 2021-08-19 Francesco Vicario , Samiya Alkhairy , Roberto Buizza , William A. Truschel

Analytical models were developed that simulate stable isotope ratios of volatile organic compounds (VOCs) near a point source contamination in the unsaturated zone. The models describe diffusive transport of VOCs, biodegradation and source…

化学物理 · 物理学 2011-09-15 D. Bouchard , F. Cornaton , P. Höhener , D. Hunkeler

We study parameter estimation for the two state model which describes the balance equation for carbon dioxide and oxygen in human respiratory system. These are nonlinear parameter dependent and because of the transport delay in the…

动力系统 · 数学 2022-07-18 Nirjal Sapkota , Janos Turi

We develop a simple three compartment model based on mass balance equations which quantitatively describes the dynamics of breath methane concentration profiles during exercise on an ergometer. With the help of this model it is possible to…

The nonlinear features of the relationships between concentrations of aerosol and volatile organic compounds (VOC) and oxides of nitrogen (NOx) in urban environments are derived directly from data of long-term routine measurements of NOx,…

大气与海洋物理 · 物理学 2020-11-04 Igor B. Konovalov

We develop a mathematical model of the lung that can estimate independently the air flows and pressures in the upper bronchi. It accounts for the lung multi-scale properties and for the air-tissue interactions. The model equations are…

组织与器官 · 定量生物学 2025-01-27 Riccardo Di Dio , Michaël Brunengo , Benjamin Mauroy

Breath acetone represents a promising non-invasive biomarker for monitoring fat oxidation during exercise. However, its utility is limited by confounding factors, as well as by the fact that significant changes in concentration occur only…

Volatile organic compounds (VOCs) represent a novel but underexplored modality for emotion recognition. This paper presents a systematic evidence synthesis and exploratory investigation of VOC-based affective computing using low-cost…

人机交互 · 计算机科学 2025-12-25 Nicolai Plintz , Marcus Vetter , Dirk Ifenthaler

Viral spread has been intermittently threatening human life over time. Characterizing the viral concentration and modelling the viral transmission are, therefore, considered major milestones for enhancing viral detection capabilities. This…

信号处理 · 电气工程与系统科学 2020-08-11 Osama Amin , Hayssam Dahrouj , Nojood Almayouf , Tareq Y. Al-Naffouri , Basem Shihada , Mohamed-Slim Alouini

A pilot study of exhaled volatile compounds and their correlation with blood glucose levels in eight children with type 1 diabetes is reported. Five paired blood and breath samples were obtained from each child over a 6 hour period. The…

医学物理 · 物理学 2013-03-19 S Stevens , C Garner , C Wei , R Greenwood , J Hamilton-Shield , B de Lacy Costello , N Ratcliffe , C Probert

Exhaled breath can be used in retrieving information and creating innovative communication systems. It contains several volatile organic compounds (VOCs) and biological entities that can act as health biomarkers. For instance, the breath of…

信号处理 · 电气工程与系统科学 2018-11-06 Maryam Khalid , Osama Amin , Sajid Ahmed , Basem Shihada , Mohamed-Slim Alouini

The aim of this work is to simulate the pollutants transport in buildings. Focusing mainly on the presence of CO2, firstly we resolve the airflow equations for two typical validation cases, the Rao case and the IEA case. These numerical…

数据分析、统计与概率 · 物理学 2012-12-26 D. Calogine , H. Boyer , S. Ndoumbe , C. Rivière , F. Miranville
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