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Graphs are central to the chemical sciences, providing a natural language to describe molecules, proteins, reactions, and industrial processes. They capture interactions and structures that underpin materials, biology, and medicine. This…

Biology is data-rich, and it is equally rich in concepts and hypotheses. Part of trying to understand biological processes and systems is therefore to confront our ideas and hypotheses with data using statistical methods to determine the…

定量方法 · 定量生物学 2022-06-22 Sean T. Vittadello , Michael P. H. Stumpf

It is a fascinating subject to explore how well we can understand the processes of life on the basis of fundamental laws of physics. It is emphasised that viewing biological processes as manipulation of information extracts their essential…

量子物理 · 物理学 2007-05-23 Apoorva Patel

Understanding and creating mathematics using natural mathematical language - the mixture of symbolic and natural language used by humans - is a challenging and important problem for driving progress in machine learning. As a step in this…

信息检索 · 计算机科学 2021-06-09 Sean Welleck , Jiacheng Liu , Ronan Le Bras , Hannaneh Hajishirzi , Yejin Choi , Kyunghyun Cho

Biological cells are the prototypical example of active matter. Cells sense and respond to mechanical, chemical and electrical environmental stimuli with a range of behaviors, including dynamic changes in morphology and mechanical…

计算工程、金融与科学 · 计算机科学 2017-02-28 Endre Somogyi , James A. Glazier

This paper is a reflexion on the computability of natural language semantics. It does not contain a new model or new results in the formal semantics of natural language: it is rather a computational analysis of the logical models and…

计算与语言 · 计算机科学 2016-05-16 Richard Moot , Christian Retoré

Within the biological, physical, and social sciences, there are two broad quantitative traditions: statistical and mathematical modeling. Both traditions have the common pursuit of advancing our scientific knowledge, but these traditions…

其他统计学 · 统计学 2026-03-05 Paul N Zivich

Large language models are a form of artificial intelligence systems whose primary knowledge consists of the statistical patterns, semantic relationships, and syntactical structures of language1. Despite their limited forms of "knowledge",…

人工智能 · 计算机科学 2023-10-13 Yizhen Zheng , Huan Yee Koh , Jiaxin Ju , Anh T. N. Nguyen , Lauren T. May , Geoffrey I. Webb , Shirui Pan

Large language models (LLMs) have been applied to tasks in healthcare, ranging from medical exam questions to responding to patient questions. With increasing institutional partnerships between companies producing LLMs and healthcare…

计算与语言 · 计算机科学 2024-04-10 Jesutofunmi A. Omiye , Haiwen Gui , Shawheen J. Rezaei , James Zou , Roxana Daneshjou

Programming with logic for sophisticated applications must deal with recursion and negation, which together have created significant challenges in logic, leading to many different, conflicting semantics of rules. This paper describes a…

计算机科学中的逻辑 · 计算机科学 2021-10-07 Yanhong A. Liu , Scott D. Stoller

Prompted models have demonstrated impressive few-shot learning abilities. Repeated interactions at test-time with a single model, or the composition of multiple models together, further expands capabilities. These compositions are…

Some aspects of the physical nature of language are discussed. In particular, physical models of language must exist that are efficiently implementable. The existence requirement is essential because without physical models no communication…

量子物理 · 物理学 2007-05-23 Paul Benioff

Rapid advances of technology and development of research in precision medicine domain have led to the production of different types of biomedical data. Standard medical vocabularies were shown to be limited in dealing with such…

计算机与社会 · 计算机科学 2018-07-04 Meng Wu , Yan Liu , Hongyu Kang , Si Zheng , Jiao Li , Li Hou

Declarative modeling uses symbolic expressions to represent models. With such expressions one can formalize high-level mathematical computations on models that would be difficult or impossible to perform directly on a lower-level simulation…

定量方法 · 定量生物学 2019-07-02 Eric Mjolsness

This essay considers the special character of mathematical reasoning, and draws on observations from interactive theorem proving and the history of mathematics to clarify the nature of formal and informal mathematical language. It proposes…

历史与综述 · 数学 2015-08-24 Jeremy Avigad

A unifying approach to software and hardware design generated by ideas of Idempotent Mathematics is discussed. The so-called idempotent correspondence principle for algorithms, programs and hardware units is described. A software project…

数值分析 · 数学 2025-10-20 Grigori Litvinov , Viktor Maslov , Anatoli Rodionov

Math is constructed by people for people: just as natural language corpora reflect not just propositions but the communicative goals of language users, the math data that models are trained on reflects not just idealized mathematical…

人工智能 · 计算机科学 2024-11-01 Sasha Boguraev , Ben Lipkin , Leonie Weissweiler , Kyle Mahowald

Understanding the mechanisms of interactions within cells, tissues, and organisms is crucial to driving developments across biology and medicine. Mathematical modeling is an essential tool for simulating biological systems and revealing…

分子网络 · 定量生物学 2024-08-13 Lingxia Qiao , Ali Khalilimeybodi , Nathaniel J Linden-Santangeli , Padmini Rangamani

In this article, the notion of a mathematical model in science is attempted to be enlightened from several points of view. In particular, it is shown that mathematical models are introduced differently and used differently in different…

历史与综述 · 数学 2022-05-25 Inge S. Helland

In modern electronic medical records (EMR) much of the clinically important data - signs and symptoms, symptom severity, disease status, etc. - are not provided in structured data fields, but rather are encoded in clinician generated…

计算与语言 · 计算机科学 2014-08-10 Son Doan , Mike Conway , Tu Minh Phuong , Lucila Ohno-Machado