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Cell reproduction involves replication of diverse molecule species, in contrast to simple replication system with fewer components. Here, we address why such diversity is sustained despite the efficiency of simple replication systems, using…

细胞行为 · 定量生物学 2016-07-06 Atsushi Kamimura , Kunihiko Kaneko

A great variety of molecular components is encapsulated in cells. Each of these components is replicated for cell reproduction. To address an essential role of the huge diversity of cellular components, we study a model of protocells that…

细胞行为 · 定量生物学 2019-04-18 Atsushi Kamimura , Kunihiko Kaneko

To unveil the logic of cell from a level of chemical reaction dynamics, we need to clarify how ensemble of chemicals can autonomously produce the set of chemical, without assuming a specific external control echanism. A cell consists of a…

分子网络 · 定量生物学 2007-05-23 Kunihiko Kaneko

Through extensive studies of dynamical system modeling cellular growth and reproduction, we find evidence that complexity arises in multicellular organisms naturally through evolution. Without any elaborate control mechanism, these systems…

适应与自组织系统 · 物理学 2009-10-31 Chikara Furusawa , Kunihiko Kaneko

For understanding the origin of life, it is essential to explain the development of a compartmentalized structure, which undergoes growth and division, from a set of chemical reactions. In this study, a hypercycle with two chemicals that…

细胞行为 · 定量生物学 2015-05-18 Atsushi Kamimura , Kunihiko Kaneko

A protocell model consisting of mutually catalyzing molecules is studied in order to investigate how chemical compositions are transferred recursively through cell divisions under replication errors. Depending on the path rate, the numbers…

凝聚态物理 · 物理学 2009-11-10 Kunihiko Kaneko

Dynamics maintaining diversity of cell types in a multi-cellular system are studied in relationship with the plasticity of cellular states. By adopting a simple theoretical framework for intra-cellular chemical reaction dynamics with…

细胞行为 · 定量生物学 2007-05-23 Hiroaki Takagi , Kunihiko Kaneko

The biological requirements for an ecosystem to develop and maintain species diversity are in general unknown. Here we consider a model ecosystem of sessile and mutually excluding organisms competing for space [Mathiesen et al. Phys. Rev.…

种群与进化 · 定量生物学 2012-09-10 Namiko Mitarai , Joachim Mathiesen , Kim Sneppen

As few real systems comprise indistinguishable units, diversity is a hallmark of nature. Diversity among interacting units shapes properties of collective behavior such as synchronization and information transmission. However, the benefits…

神经元与认知 · 定量生物学 2016-05-06 Leonardo L. Gollo , Mauro Copelli , James A. Roberts

The notion of (auto) catalytic networks has become a cornerstone in understanding the possibility of a sudden dramatic increase of diversity in biological evolution as well as in the evolution of social and economical systems. Here we study…

其他凝聚态物理 · 物理学 2016-10-05 Rudolf Hanel , Stuart A. Kauffman , Stefan Thurner

As cells grow and divide under a given environment, they become crowded and resources are limited, as seen in bacterial biofilms and multicellular aggregates. These cells often show strong interactions through exchanging chemicals, as in…

细胞行为 · 定量生物学 2017-02-08 Jumpei F Yamagishi , Nen Saito , Kunihiko Kaneko

The evolution of complexity has been a central theme for Biology [2] and Artificial Life research [1]. It is generally agreed that complexity has increased in our universe, giving way to life, multi-cellularity, societies, and systems of…

种群与进化 · 定量生物学 2011-09-06 Carlos Gershenson , Tom Lenaerts

Dynamics maintaining diversity of cell types in a multi-cellular system are studied in relationship with the plasticity of cellular states. First, we introduce a new theoretical framework, reaction-diffusion system on `chemical species…

适应与自组织系统 · 物理学 2007-05-23 Hiroaki Takagi , Kunihiko Kaneko

Species coexistence is one of the central themes in modern ecology. Coexistence is a prerequisite of biological diversity. However, the question arises how biodiversity can be reconciled with the statement of competition theory, which…

种群与进化 · 定量生物学 2007-08-17 Dalius Balciunas

Microbial communities display extreme diversity. A variety of strains or species coexist even when limited by a single resource. It has been argued that metabolite secretion creates new niches and facilitates such diversity. Nonetheless, it…

种群与进化 · 定量生物学 2020-02-05 Jumpei F Yamagishi , Nen Saito , Kunihiko Kaneko

A fundamental issue discussed in evolutionary biology is the transition from unicellular to multicellular organisms. Here we develop non-robust models provided in [1] and attempt to get robust models investigated how differentiation of…

种群与进化 · 定量生物学 2015-12-15 Denis Tverskoy

Modern biological tools have made it possible to unequivocally demonstrate the deep relationship among species in terms of genes and basic molecular mechanisms. In addition, results from genetic, physical and physiological approaches…

种群与进化 · 定量生物学 2019-03-11 Jacques H. Daniel

We demonstrate diversification rather than optimisation for highly interacting organisms in a well mixed biological system by means of a simple model and reference to experiment, and find the cause to be the complex network of interactions…

种群与进化 · 定量生物学 2007-05-23 Daniel Lawson , Henrik Jeldtoft Jensen , Kunihiko Kaneko

During overflow metabolism, cells excrete glycolytic byproducts when growing under aerobic conditions in a seemingly wasteful fashion. While potentially advantageous for microbes with finite oxidative capacity, its role in higher organisms…

We explain how hierarchical organization of biological systems emerges naturally during evolution, through a transition in the units of individuality. We will show how these transitions are the result of competing selective forces operating…

种群与进化 · 定量生物学 2015-06-16 Cameron Smith , Matthieu Laneuville , Nicholas Guttenberg
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