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Rule-based methods are often used for assigning fiber orientation to cardiac anatomical models. However, existing methods have been developed using data mostly from the left ventricle. As a consequence, fiber information obtained from…

Medical image segmentation is one of the important tasks of computer-aided diagnosis in medical image analysis. Since most medical images have the characteristics of blurred boundaries and uneven intensity distribution, through existing…

计算机视觉与模式识别 · 计算机科学 2021-06-09 Sixing Yin , Yameng Han , Shufang Li

This work analyzes the viscous flow and elastic deformation created by the forced axial motion of a rigid cylinder within an elastic liquid-filled tube. The examined configuration is relevant to various minimally invasive medical procedures…

软凝聚态物质 · 物理学 2019-05-15 Amit Vurgaft , Shai B. Elbaz , Amir D. Gat

Deformable shape modeling approaches that describe objects in terms of their medial axis geometry (e.g., m-reps [Pizer et al., 2003]) yield rich geometrical features that can be useful for analyzing the shape of sheet-like biological…

图形学 · 计算机科学 2019-03-04 Paul A. Yushkevich , Ahmed Aly , Jiancong Wang , Long Xie , Robert C. Gorman , Laurent Younes , Alison Pouch

The liver has a unique blood supply system and plays an important role in the human blood circulatory system. Thus, hemodynamic problems related to the liver serve as an important part in clinical diagnosis and treatment. Although…

数值分析 · 数学 2021-10-15 Ting Wu , Keqin Liu , Emily Fainman , Ying Wang

We present a Lagrangian analysis of turbulent blood flow in the human left heart using high-fidelity simulations based on a patient-specific anatomical model. Leveraging a fully coupled fluid-structure-electrophysiology interaction (FSEI)…

流体动力学 · 物理学 2025-06-13 Fabio Guglietta , Martino Andrea Scarpolini , Francesco Viola , Luca Biferale

An arteriovenous fistula, created by artificially connecting segments of a patient's vasculature, is the preferred way to gain access to the bloodstream for kidney dialysis. The increasing power and availability of supercomputing…

医学物理 · 物理学 2021-06-14 J. W. S. McCullough , P. V. Coveney

Cardiac fluid dynamics fundamentally involves interactions between complex blood flows and the structural deformations of the muscular heart walls and the thin, flexible valve leaflets. There has been longstanding scientific, engineering,…

Vortical blood flow in the human left ventricular (LV) inflow initiates from the mitral valve (MV) and evolves within the LV during diastolic E-filling. Hence, vortical flow links MV and LV hemodynamics. This study sought to elucidate and…

Ventricular fibrillation, the major reason behind sudden cardiac death, is turbulent cardiac electrical activity in which rapid, irregular disturbances in the spatiotemporal electrical activation of the heart makes it incapable of any…

混沌动力学 · 物理学 2009-11-07 Sitabhra Sinha , Ashwin Pande , Rahul Pandit

Although atrial fibrillation (AF), a common arrhythmia, frequently presents in patients with underlying valvular disease, its hemodynamic contributions are not fully understood. The present work aimed to computationally study how physical…

流体动力学 · 物理学 2016-07-27 Stefania Scarsoglio , Andrea Saglietto , Fiorenzo Gaita , Luca Ridolfi , Matteo Anselmino

Lumped method (Electrical analogy) is a quick and easy way to model human cardiovascular system. In this paper Lumped method is used for simulating a complete model. It describes a 36-vessel model and cardiac system of human body with…

This experimental in vitro work investigates material transport properties in a model left ventricle in the case of aortic regurgitation, a valvular disease characterized by a leaking aortic valve and consequently double-jet filling within…

流体动力学 · 物理学 2019-03-18 Giuseppe Di Labbio , Jérôme Vétel , Lyes Kadem

Cardiac left ventricle (LV) quantification provides a tool for diagnosing cardiac diseases. Automatic calculation of all relevant LV indices from cardiac MR images is an intricate task due to large variations among patients and deformation…

图像与视频处理 · 电气工程与系统科学 2020-02-04 Nils Gessert , Alexander Schlaefer

Recently, the Less In More Out device, a fluidically actuated soft total artificial heart was proposed. This device uses arrays of pouch motors to achieve a positive fluidic lever when pneumatically actuated against physiological…

组织与器官 · 定量生物学 2026-01-08 Marin Lauber , Maziar Arfaee , Mathias Peirlinck

In cases of pressure or volume overload, probing cardiac function may be difficult because of the interactions between shape and deformations.In this work, we use the LDDMM framework and parallel transport to estimate and reorient…

计算机视觉与模式识别 · 计算机科学 2021-02-18 Nicolas Guigui , Pamela Moceri , Maxime Sermesant , Xavier Pennec

Introduction: Stenotic aortic valve disease (AS) causes pressure overload of the left ventricle (LV) that may trigger adverse remodeling and precipitate progression towards heart failure (HF). As myocardial energetics can be impaired during…

In this work, we attempt to optimize the design of an electromagnetic induction device that captures the energy from the arterial wall pulsation for the purpose of powering implantable medical devices. The artery comes through a flexible…

Left ventricular (LV) stiffness and contractility, characterized by the end-diastolic and end-systolic pressure-volume relationships (EDPVR & ESPVR), are two important indicators of the performance of the human heart. Although much research…

医学物理 · 物理学 2023-08-22 Yunxiao Zhang , Moritz Kalhöfer-Köchling , Eberhard Bodenschatz , Yong Wang

We analyze left atrium haemodynamics, highlighting differences among healthy individuals and patients affected by atrial fibrillation. The computational study is based on patient-specific geometries of the left atria to simulate blood flow…

流体动力学 · 物理学 2022-10-06 Mattia Corti , Alberto Zingaro , Luca Dede' , Alfio Maria Quarteroni