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Bayesian spatial modeling provides a flexible framework for whole-brain fMRI analysis by explicitly incorporating spatial dependencies, overcoming the limitations of traditional massive univariate approaches that lead to information waste.…

统计方法学 · 统计学 2025-11-18 Yuan Zhong , Gang Chen , Paul A. Taylor , Jian Kang

Illness-death models are a class of stochastic models inside the multi-state framework. In those models, individuals are allowed to move over time between different states related to illness and death. They are of special interest when…

应用统计 · 统计学 2022-10-14 Fran Llopis-Cardona , Carmen Armero , Gabriel Sanfélix-Gimeno

Disease maps are an important tool in cancer epidemiology used for the analysis of geographical variations in disease rates and the investigation of environmental risk factors underlying spatial patterns. Cancer maps help epidemiologists…

应用统计 · 统计学 2020-12-08 Leiwen Gao , Sudipto Banerjee , Abhirup Datta

Multiple Sclerosis (MS) and microvascular leukoencephalopathy are two distinct neurological conditions, the first caused by focal autoimmune inflammation in the central nervous system, the second caused by chronic white matter damage from…

图像与视频处理 · 电气工程与系统科学 2021-01-19 Christopher Vogelsanger , Christian Federau

Multi-parametric magnetic resonance imaging (mpMRI) plays an increasingly important role in the diagnosis of prostate cancer. Various computer-aided detection algorithms have been proposed for automated prostate cancer detection by…

应用统计 · 统计学 2020-01-22 Jin Jin , Lin Zhang , Ethan Leng , Gregory J. Metzger , Joseph S. Koopmeiners

Recent evidence has shown that structural magnetic resonance imaging (MRI) is an effective tool for Alzheimer's disease (AD) prediction and diagnosis. While traditional MRI-based diagnosis uses images acquired at a single time point, a…

应用统计 · 统计学 2021-11-02 Xiaowu Dai

Motivated by recent data analyses in biomedical imaging studies, we consider a class of image-on-scalar regression models for imaging responses and scalar predictors. We propose using flexible multivariate splines over triangulations to…

统计方法学 · 统计学 2021-06-04 Shan Yu , Guannan Wang , Li Wang , Lijian Yang

Explainable artificial intelligence (XAI) methods have been proposed to interpret model decisions in classification and, more recently, in semantic segmentation. However, instance-level XAI for semantic segmentation, namely explanations…

With the advance of imaging technology, digital pathology imaging of tumor tissue slides is becoming a routine clinical procedure for cancer diagnosis. This process produces massive imaging data that capture histological details in high…

统计方法学 · 统计学 2020-12-10 Qiwei Li , Xinlei Wang , Faming Liang , Guanghua Xiao

Identifying disease-indicative genes is critical for deciphering disease mechanisms and has attracted significant interest in biomedical research. Spatial transcriptomics offers unprecedented insights for the detection of disease-specific…

统计方法学 · 统计学 2024-09-05 Qicheng Zhao , Qihuang Zhang

Multiple sclerosis lesion activity segmentation is the task of detecting new and enlarging lesions that appeared between a baseline and a follow-up brain MRI scan. While deep learning methods for single-scan lesion segmentation are common,…

计算机视觉与模式识别 · 计算机科学 2020-06-02 Nils Gessert , Marcel Bengs , Julia Krüger , Roland Opfer , Ann-Christin Ostwaldt , Praveena Manogaran , Sven Schippling , Alexander Schlaefer

Multiple sclerosis (MS) is a chronic autoimmune disease that affects the central nervous system. The progression and severity of MS varies by individual, but it is generally a disabling disease. Although medications have been developed to…

应用统计 · 统计学 2013-03-06 Joyce C. Ho , Joydeep Ghosh , KP Unnikrishnan

The field of computer vision is undergoing a paradigm shift toward large-scale foundation model pre-training via self-supervised learning (SSL). Leveraging large volumes of unlabeled brain MRI data, such models can learn anatomical priors…

图像与视频处理 · 电气工程与系统科学 2026-01-15 Petros Koutsouvelis , Matej Gazda , Leroy Volmer , Sina Amirrajab , Kamil Barbierik , Branislav Setlak , Jakub Gazda , Peter Drotar

Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous system (CNS) that results in focal injury to the grey and white matter. The presence of white matter lesions biases morphometric analyses such as…

计算机视觉与模式识别 · 计算机科学 2019-09-09 Hao Xiong , Chaoyue Wang , Dacheng Tao , Michael Barnett , Chenyu Wang

In recent years, disease mapping studies have become a routine application within geographical epidemiology and are typically analysed within a Bayesian hierarchical model formulation. A variety of model formulations for the latent level…

统计方法学 · 统计学 2016-01-07 Andrea Riebler , Sigrunn H. Sørbye , Daniel Simpson , Håvard Rue

There is a growing interest to get a fully MR based radiotherapy. The most important development needed is to obtain improved bone tissue estimation. The existing model-based methods perform poorly on bone tissues. This paper was aimed at…

应用统计 · 统计学 2019-04-02 Fekadu L. Bayisa , Jun Yu

This is an empirical study to investigate the impact of scanner effects when using machine learning on multi-site neuroimaging data. We utilize structural T1-weighted brain MRI obtained from two different studies, Cam-CAN and UK Biobank.…

图像与视频处理 · 电气工程与系统科学 2019-10-11 Ben Glocker , Robert Robinson , Daniel C. Castro , Qi Dou , Ender Konukoglu

The most common reason for spinal surgery in elderly patients is lumbar spinal stenosis(LSS). For LSS, treatment decisions based on clinical and radiological information as well as personal experience of the surgeon shows large variance.…

Skin lesion segmentation is one of the crucial steps for an efficient non-invasive computer-aided early diagnosis of melanoma. This paper investigates how color information, besides saliency, can be used to determine the pigmented lesion…

图像与视频处理 · 电气工程与系统科学 2021-11-08 Giuliana Ramella