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相关论文: Stabilizing Sparse Cox Model using Clinical Struct…

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In a data-scarce field such as healthcare, where models often deliver predictions on patients with rare conditions, the ability to measure the uncertainty of a model's prediction could potentially lead to improved effectiveness of decision…

机器学习 · 统计学 2020-05-26 Lotta Meijerink , Giovanni Cinà , Michele Tonutti

Accurately predicting hospital length-of-stay at the time a patient is admitted to hospital may help guide clinical decision making and resource allocation. In this study we aim to build a decision support system that predicts hospital…

人工智能 · 计算机科学 2023-08-08 Mucahit Cevik , Can Kavaklioglu , Fahad Razak , Amol Verma , Ayse Basar

Methods that address data shifts usually assume full access to multiple datasets. In the healthcare domain, however, privacy-preserving regulations as well as commercial interests limit data availability and, as a result, researchers can…

机器学习 · 统计学 2022-05-03 Tal El-Hay , Chen Yanover

Deep learning-based predictive models, leveraging Electronic Health Records (EHR), are receiving increasing attention in healthcare. An effective representation of a patient's EHR should hierarchically encompass both the temporal…

机器学习 · 计算机科学 2024-05-08 Jiayuan Chen , Changchang Yin , Yuanlong Wang , Ping Zhang

We propose a novel frailty model with change points applying random effects to a Cox proportional hazard model to adjust the heterogeneity between clusters. Because the frailty model includes random effects, the parameters are estimated…

统计方法学 · 统计学 2023-01-12 Masahiro Kojima , Shunichiro Orihara

Electronic health records (EHR) are increasingly being used for constructing disease risk prediction models. Feature engineering in EHR data however is challenging due to their highly dimensional and heterogeneous nature. Low-dimensional…

计算与语言 · 计算机科学 2018-11-29 Spiros Denaxas , Pontus Stenetorp , Sebastian Riedel , Maria Pikoula , Richard Dobson , Harry Hemingway

Cox proportional hazards model is one of the most popular models in biomedical data analysis. There have been continuing efforts to improve the flexibility of such models for complex signal detection, for example, via additive functions.…

统计方法学 · 统计学 2022-05-25 Boyi Guo , Nengjun Yi

Clinical event sequences consist of hundreds of clinical events that represent records of patient care in time. Developing accurate predictive models of such sequences is of a great importance for supporting a variety of models for…

机器学习 · 计算机科学 2023-08-23 Jeong Min Lee , Milos Hauskrecht

Electronic health records arise from the complex interaction between patients and the healthcare system. This observation process of interactions, referred to as clinical presence, often impacts observed outcomes. When using electronic…

机器学习 · 计算机科学 2025-08-08 Vincent Jeanselme , Glen Martin , Matthew Sperrin , Niels Peek , Brian Tom , Jessica Barrett

This paper introduces new techniques for using convex optimization to fit input-output data to a class of stable nonlinear dynamical models. We present an algorithm that guarantees consistent estimates of models in this class when a small…

最优化与控制 · 数学 2013-03-19 Mark M. Tobenkin , Ian R. Manchester , Alexandre Megretski

For sparse high-dimensional regression problems, Cox and Battey [1, 9] emphasised the need for confidence sets of models: an enumeration of those small sets of variables that fit the data equivalently well in a suitable statistical sense.…

统计方法学 · 统计学 2025-06-10 R. M. Lewis , H. S. Battey

Foundation models (FMs) trained on electronic health records (EHRs) have shown strong performance on a range of clinical prediction tasks. However, adapting these models to local health systems remains challenging due to limited data…

Interval-censoring frequently occurs in studies of chronic diseases where disease status is inferred from intermittently collected biomarkers. Although many methods have been developed to analyze such data, they typically assume perfect…

统计方法学 · 统计学 2026-05-26 Yuhao Deng , Donglin Zeng , Yuanjia Wang

Building models for health prediction based on Electronic Health Records (EHR) has become an active research area. EHR patient journey data consists of patient time-ordered clinical events/visits from patients. Most existing studies focus…

机器学习 · 计算机科学 2022-07-18 Yuxi Liu , Zhenhao Zhang , Antonio Jimeno Yepes , Flora D. Salim

Increasingly, medical research is dependent on data collected for non-research purposes, such as electronic health records data (EHR). EHR data and other large databases can be prone to measurement error in key exposures, and unadjusted…

统计方法学 · 统计学 2020-05-13 Kyunghee Han , Thomas Lumley , Bryan E. Shepherd , Pamela A. Shaw

Multimodal clinical records contain structured measurements and clinical notes recorded over time, offering rich temporal information about the evolution of patient health. Yet these observations are sparse, and whether they are recorded…

机器学习 · 计算机科学 2026-04-24 Zihan Liang , Ziwen Pan , Ruoxuan Xiong

This study addresses the challenge of predicting post-stroke rigidity by emphasizing feature interactions through graph-based explainable AI. Post-stroke rigidity, characterized by increased muscle tone and stiffness, significantly affects…

Electronic records contain sequences of events, some of which take place all at once in a single visit, and others that are dispersed over multiple visits, each with a different timestamp. We postulate that fine temporal detail, e.g.,…

机器学习 · 计算机科学 2019-04-30 Mohammad Taha Bahadori , Zachary Chase Lipton

Medical time series analysis is challenging due to data sparsity, noise, and highly variable recording lengths. Prior work has shown that stochastic sparse sampling effectively handles variable-length signals, while retrieval-augmented…

We consider structural equation modeling (SEM) with latent variables for diffusion processes based on high-frequency data. The quasi-likelihood estimators for parameters in the SEM are proposed. The goodness-of-fit test is derived from the…

统计理论 · 数学 2023-06-09 Shogo Kusano , Masayuki Uchida