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Gene expression datasets offer insights into gene regulation mechanisms, biochemical pathways, and cellular functions. Additionally, comparing gene expression profiles between disease and control patients can deepen the understanding of…

机器学习 · 计算机科学 2025-03-27 Rita T. Sousa , Heiko Paulheim

This paper introduces and demonstrates a computational pipeline for the statistical analysis of shape graph datasets, namely geometric networks embedded in 2D or 3D spaces. Unlike traditional abstract graphs, our purpose is not only to…

机器学习 · 计算机科学 2026-02-19 Murad Hossen , Demetrio Labate , Nicolas Charon

Medical imaging is an essential tool for diagnosing and treating diseases. However, lacking medical images can lead to inaccurate diagnoses and ineffective treatments. Generative models offer a promising solution for addressing medical…

图像与视频处理 · 电气工程与系统科学 2024-01-02 M. AbdulRazek , G. Khoriba , M. Belal

Many processes, from gene interaction in biology to computer networks to social media, can be modeled more precisely as temporal hypergraphs than by regular graphs. This is because hypergraphs generalize graphs by extending edges to connect…

人机交互 · 计算机科学 2021-05-12 Maximilian T. Fischer , Devanshu Arya , Dirk Streeb , Daniel Seebacher , Daniel A. Keim , Marcel Worring

Facial Image inpainting aim is to restore the missing or corrupted regions in face images while preserving identity, structural consistency and photorealistic image quality, a task specifically created for photo restoration. Though there…

计算机视觉与模式识别 · 计算机科学 2026-02-17 Abhigyan Bhattacharya , Hiranmoy Roy , Debotosh Bhattacharjee

Predicting human gaze scanpaths is crucial for understanding visual attention, with applications in human-computer interaction, autonomous systems, and cognitive robotics. While deep learning models have advanced scanpath prediction, most…

计算机视觉与模式识别 · 计算机科学 2025-08-01 Giuseppe Cartella , Vittorio Cuculo , Alessandro D'Amelio , Marcella Cornia , Giuseppe Boccignone , Rita Cucchiara

Integrating heterogeneous biomedical data including imaging, omics, and clinical records supports accurate diagnosis and personalised care. Graph-based models fuse such non-Euclidean data by capturing spatial and relational structure, yet…

基因组学 · 定量生物学 2025-05-06 Alireza Sadeghi , Farshid Hajati , Ahmadreza Argha , Nigel H Lovell , Min Yang , Hamid Alinejad-Rokny

In healthcare, AI techniques are widely used for tasks like risk assessment and anomaly detection. Despite AI's potential as a valuable assistant, its role in complex medical data analysis often oversimplifies human-AI collaboration…

人机交互 · 计算机科学 2024-07-23 Yang Ouyang , Chenyang Zhang , He Wang , Tianle Ma , Chang Jiang , Yuheng Yan , Zuoqin Yan , Xiaojuan Ma , Chuhan Shi , Quan Li

Biologists are leading current research on genome characterization (sequencing, alignment, transcription), providing a huge quantity of raw data about many genome organisms. Extracting knowledge from this raw data is an important process…

定量方法 · 定量生物学 2007-05-23 Nicolas Férey , Pierre-Emmanuel Gros , Joan Hérisson , Rachid Gherbi

It has been shown that genome spatial structures largely affect both genome activity and DNA function. Knowing this, many researchers are currently attempting to accurately model genome structures. Despite these increased efforts there…

基因组学 · 定量生物学 2015-07-24 Jackson Nowotny , Avery Wells , Lingfei Xu , Renzhi Cao , Tuan Trieu , Chenfeng He , Jianlin Cheng

Motivation: Network visualizations of complex biological datasets usually result in 'hairball' images, which do not discriminate network modules. Results: We present the EntOptLayout Cytoscape plug-in based on a recently developed network…

Graph Neural Networks (GNNs) have achieved significant success across various applications. However, their complex structures and inner workings can be challenging for non-AI experts to understand. To address this issue, this study presents…

人机交互 · 计算机科学 2025-12-18 Yilin Lu , Chongwei Chen , Yuxin Chen , Kexin Huang , Marinka Zitnik , Qianwen Wang

Embedding visual representations within original hierarchical tables can mitigate additional cognitive load stemming from the division of users' attention. The created hierarchical table visualizations can help users understand and explore…

人机交互 · 计算机科学 2024-05-28 Guozheng Li , Peng He , Xinyu Wang , Runfei Li , Chi Harold Liu , Chuangxin Ou , Dong He , Guoren Wang

Gene-gene interactions play a crucial role in the manifestation of complex human diseases. Uncovering significant gene-gene interactions is a challenging task. Here, we present an innovative approach utilizing data-driven computational…

人工智能 · 计算机科学 2024-10-22 Yifan Wu , Yuntao Yang , Zirui Liu , Zhao Li , Khushbu Pahwa , Rongbin Li , Wenjin Zheng , Xia Hu , Zhaozhuo Xu

Finding interesting phenomena is the core of scientific discovery, but it is a manual, ill-defined concept. We present an integrative pipeline for automating the discovery of interesting simple hypotheses (feature-target relations with…

定量方法 · 定量生物学 2025-09-09 Dan Ofer , Michal Linial , Dafna Shahaf

The remarkable success of foundation models has sparked growing interest in their application to single-cell biology. Models like Geneformer and scGPT promise to serve as versatile tools in this specialized field. However, representing a…

定量方法 · 定量生物学 2024-11-12 Jiabei Cheng , Jiachen Li , Kaiyuan Yang , Hongbin Shen , Ye Yuan

Recent advances in deep neuroevolution have demonstrated that evolutionary algorithms, such as evolution strategies (ES) and genetic algorithms (GA), can scale to train deep neural networks to solve difficult reinforcement learning (RL)…

神经与进化计算 · 计算机科学 2018-05-04 Rui Wang , Jeff Clune , Kenneth O. Stanley

We present ScaleTrotter, a conceptual framework for an interactive, multi-scale visualization of biological mesoscale data and, specifically, genome data. ScaleTrotter allows viewers to smoothly transition from the nucleus of a cell to the…

图形学 · 计算机科学 2024-04-25 Sarkis Halladjian , Haichao Miao , David Kouřil , M. Eduard Gröller , Ivan Viola , Tobias Isenberg

Unstructured data(e.g., images, videos, PDF files, etc.) contain semantic information, for example, the facial feature of a person and the plate number of a vehicle. There could be semantic relationships between data items which are not…

数据库 · 计算机科学 2022-10-11 Zihao Zhao , Zhihong Shen , Mingjie Tang , Chuan Hu , Huajin Wang , Yuanchun Zhou

As one of the most important affective signals, facial affect analysis (FAA) is essential for developing human-computer interaction systems. Early methods focus on extracting appearance and geometry features associated with human affects…

计算机视觉与模式识别 · 计算机科学 2022-02-14 Yang Liu , Xingming Zhang , Yante Li , Jinzhao Zhou , Xin Li , Guoying Zhao