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Introduction: It is challenging at baseline to predict when and which individuals who meet criteria for mild cognitive impairment (MCI) will ultimately progress to Alzheimer's disease (AD) dementia. Methods: A deep learning method is…

计算机视觉与模式识别 · 计算机科学 2019-04-17 Hongming Li , Mohamad Habes , David A. Wolk , Yong Fan

This paper explores deterioration in Alzheimers Disease using Machine Learning. Subjects were split into two datasets based on baseline diagnosis (Cognitively Normal, Mild Cognitive Impairment), with outcome of deterioration at final visit…

机器学习 · 计算机科学 2023-06-21 Henry Musto , Daniel Stamate , Ida Pu , Daniel Stahl

Multiple modalities of biomarkers have been proved to be very sensitive in assessing the progression of Alzheimer's disease (AD), and using these modalities and machine learning algorithms, several approaches have been proposed to assist in…

机器学习 · 统计学 2017-12-05 Chen Fang , Panuwat Janwattanapong , Chunfei Li , Malek Adjouadi

Autism spectrum disorder (ASD) is a highly disabling mental disease that brings significant impairments of social interaction ability to the patients, making early screening and intervention of ASD critical. With the development of the…

计算机视觉与模式识别 · 计算机科学 2025-04-08 Ruimin Ma , Ruitao Xie , Yanlin Wang , Jintao Meng , Yanjie Wei , Wenhui Xi , Yi Pan

Alzheimer Disease poses a significant challenge, necessitating early detection for effective intervention. MRI is a key neuroimaging tool due to its ease of use and cost effectiveness. This study analyzes machine learning methods for MRI…

神经元与认知 · 定量生物学 2024-08-12 Alwani Liyana Ahmad , Jose Sanchez-Bornot , Roberto C. Sotero , Damien Coyle , Zamzuri Idris , Ibrahima Faye

Alzheimers disease is a deadly neurological condition, impairing important memory and brain functions. Alzheimers disease promotes brain shrinkage, ultimately leading to dementia. Dementia diagnosis typically takes 2.8 to 4.4 years after…

Dementia is a group of irreversible, chronic, and progressive neurodegenerative disorders resulting in impaired memory, communication, and thought processes. In recent years, clinical research advances in brain aging have focused on the…

This paper aims to develop a new deep learning-inspired gaming approach for early detection of dementia. This research integrates a robust convolutional neural network (CNN)-based model for early dementia detection using health metrics data…

计算机视觉与模式识别 · 计算机科学 2024-12-31 Paramita Kundu Maji , Soubhik Acharya , Priti Paul , Sanjay Chakraborty , Saikat Basu

Alzheimer's Disease is a devastating neurological disorder that is increasingly affecting the elderly population. Early and accurate detection of Alzheimer's is crucial for providing effective treatment and support for patients and their…

图像与视频处理 · 电气工程与系统科学 2023-04-27 Krishna Mahapatra , Selvakumar R

Background and Aim: Accurate classification of Magnetic Resonance Images (MRI) is essential to accurately predict Mild Cognitive Impairment (MCI) to Alzheimer's Disease (AD) conversion. Meanwhile, deep learning has been successfully…

计算机视觉与模式识别 · 计算机科学 2021-09-03 Kshitiz Shrestha , Omar Hisham Alsadoon , Abeer Alsadoon , Tarik A. Rashid , Rasha S. Ali , P. W. C. Prasad , Oday D. Jerew

Early diagnosis of dementia, particularly in the prodromal stage (i.e., mild cognitive impairment, or MCI), has become a research and clinical priority but remains challenging. Automated analysis of the drawing process has been studied as a…

信号处理 · 电气工程与系统科学 2022-11-17 Yasunori Yamada , Masatomo Kobayashi , Kaoru Shinkawa , Miyuki Nemoto , Miho Ota , Kiyotaka Nemoto , Tetsuaki Arai

Autism Spectrum Disorder (ASD) is on the rise and constantly growing. Earlier identify of ASD with the best outcome will allow someone to be safe and healthy by proper nursing. Humans can hardly estimate the present condition and stage of…

机器学习 · 计算机科学 2021-01-28 Koushik Chowdhury , Mir Ahmad Iraj

Collecting and accessing a large amount of medical data is very time-consuming and laborious, not only because it is difficult to find specific patients but also because it is required to resolve the confidentiality of a patient's medical…

声音 · 计算机科学 2021-03-04 Junghyun Koo , Jie Hwan Lee , Jaewoo Pyo , Yujin Jo , Kyogu Lee

Multi-modal biological, imaging, and neuropsychological markers have demonstrated promising performance for distinguishing Alzheimer's disease (AD) patients from cognitively normal elders. However, it remains difficult to early predict when…

计算机视觉与模式识别 · 计算机科学 2019-01-08 Hongming Li , Yong Fan

Prediction of the cognitive evolution of a person susceptible to develop a neurodegenerative disorder is crucial to provide an appropriate treatment as soon as possible. In this paper we propose a 3D siamese network designed to extract…

图像与视频处理 · 电气工程与系统科学 2019-09-04 Cecilia Ostertag , Marie Beurton-Aimar , Thierry Urruty

Major depressive disorder (MDD) is a complex psychiatric disorder that affects the lives of hundreds of millions of individuals around the globe. Even today, researchers debate if morphological alterations in the brain are linked to MDD,…

定量方法 · 定量生物学 2025-01-27 Roberto Goya-Maldonado , Tracy Erwin-Grabner , Ling-Li Zeng , Christopher R. K. Ching , Andre Aleman , Alyssa R. Amod , Zeynep Basgoze , Francesco Benedetti , Bianca Besteher , Katharina Brosch , Robin Bülow , Romain Colle , Colm G. Connolly , Emmanuelle Corruble , Baptiste Couvy-Duchesne , Kathryn Cullen , Udo Dannlowski , Christopher G. Davey , Annemiek Dols , Jan Ernsting , Jennifer W. Evans , Lukas Fisch , Paola Fuentes-Claramonte , Ali Saffet Gonul , Ian H. Gotlib , Hans J. Grabe , Nynke A. Groenewold , Dominik Grotegerd , Tim Hahn , J. Paul Hamilton , Laura K. M. Han , Ben J. Harrison , Tiffany C. Ho , Neda Jahanshad , Alec J. Jamieson , Andriana Karuk , Tilo Kircher , Bonnie Klimes-Dougan , Sheri-Michelle Koopowitz , Thomas Lancaster , Ramona Leenings , Meng Li , David E. J. Linden , Frank P. MacMaster , David M. A. Mehler , Susanne Meinert , Elisa Melloni , Bryon A. Mueller , Benson Mwangi , Igor Nenadić , Amar Ojha , Yasumasa Okamoto , Mardien L. Oudega , Brenda W. J. H. Penninx , Sara Poletti , Edith Pomarol-Clotet , Maria J. Portella , Elena Pozzi , Joaquim Radua , Elena Rodríguez-Cano , Matthew D. Sacchet , Raymond Salvador , Anouk Schrantee , Kang Sim , Jair C. Soares , Aleix Solanes , Dan J. Stein , Frederike Stein , Aleks Stolicyn , Sophia I. Thomopoulos , Yara J. Toenders , Aslihan Uyar-Demir , Eduard Vieta , Yolanda Vives-Gilabert , Henry Völzke , Martin Walter , Heather C. Whalley , Sarah Whittle , Nils Winter , Katharina Wittfeld , Margaret J. Wright , Mon-Ju Wu , Tony T. Yang , Carlos Zarate , Dick J. Veltman , Lianne Schmaal , Paul M. Thompson

Alzheimer's disease is one of the most common types of neurodegenerative disease, characterized by the accumulation of amyloid-beta plaque and tau tangles. Recently, deep learning approaches have shown promise in Alzheimer's disease…

图像与视频处理 · 电气工程与系统科学 2024-07-03 Gia Minh Hoang , Youngjoo Lee , Jae Gwan Kim

Alzheimers disease (AD) is a severe neurological brain disorder. It is not curable, but earlier detection can help improve symptoms in a great deal. The machine learning based approaches are popular and well motivated models for medical…

图像与视频处理 · 电气工程与系统科学 2024-05-17 Lilia Lazli

We propose a novel optimization framework to predict clinical severity from resting state fMRI (rs-fMRI) data. Our model consists of two coupled terms. The first term decomposes the correlation matrices into a sparse set of representative…

神经元与认知 · 定量生物学 2024-11-25 Niharika Shimona D'Souza , Mary Beth Nebel , Nicholas Wymbs , Stewart H. Mostofsky , Archana Venkataraman

A three-dimensional convolutional neural network was developed to classify T1-weighted brain MRI scans as healthy or Alzheimer. The network comprises 3D convolution, pooling, batch normalization, dense ReLU layers, and a sigmoid output.…

图像与视频处理 · 电气工程与系统科学 2025-06-18 Thien Nhan Vo , Bac Nam Ho