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The purpose of this study is to measure the internal radiation dose using a human blood sample. In the literature, there is no process that allows the direct measurement of the internal radiation dose received by a person. The luminescence…

医学物理 · 物理学 2016-01-15 Ayse Güneş Tanır , Özge Güleç

In this study it was shown that it is possible to determine radiation doses from external beam therapy both directly and retrospectively from a human blood sample. To the best of our knowledge no other studies exist on the direct…

医学物理 · 物理学 2016-01-15 AG Tanir , O Gulec , E Sahiner , MH Bolukdemir , K Koc , N Meric , SK Keles , O Kucuk

A new approach to three-dimensional (3D) dosimetry based on optically-stimulated luminescence (OSL) is presented. By embedding OSL-active particles into a transparent silicone matrix (PDMS), the well-established dosimetric properties of an…

In radiation oncology, inter-fractional dosimetry is often performed with luminescent dosimeters to verify the accurate delivery of a plan and ensure patient safety. Optically stimulated luminescent detectors (OSLDs) are the most commonly…

医学物理 · 物理学 2024-07-23 H. Davis , J. Siebers , K. Wijesooriya , M. Mistro

Recently, Yamashita et al. reported direct measurements of ionizing radiation doses to individual organs in postmortem (using OSL dosimetry) that were exposed in the most frequent clinical CT scan protocols, corresponding to the whole body,…

We use long-term electron and proton in-situ measurements made by the CXD particle instruments, developed by Los Alamos National Laboratory and carried on board GPS satellites, to determine total ionizing dose (TID) values and daily/yearly…

空间物理 · 物理学 2020-12-02 Yue Chen , Matthew R. Carver , Steven K. Morley , Andrew S. Hoover

Worldwide several radiation sources contribute to the delivered dose to the human population. This radiation also acts as natural background when detecting radiation, for instance from radioactive sources. In this work a medium-size plastic…

仪器与探测器 · 物理学 2017-09-20 Luis Peralta

Two rods made from sol-gel silica have been doped with Ce ions or co-doped with Ce and Tb ions respectively. First, a thermoluminescence (TL) characterization of the trapping and luminescence parameters is carried out to understand the…

Cone beam CT (CBCT) has been widely used for patient setup in image guided radiation therapy (IGRT). Radiation dose from CBCT scans has become a clinical concern. The purposes of this study are 1) to commission a GPU-based Monte Carlo (MC)…

Purpose: Various dose calculation algorithms are available for radiation therapy for cancer patients. However, these algorithms are faced with the tradeoff between efficiency and accuracy. The fast algorithms are generally less accurate,…

医学物理 · 物理学 2020-07-01 Yixun Xing , Dan Nguyen , Weiguo Lu , Ming Yang , Steve Jiang

With the advancement of treatment modalities in radiation therapy for cancer patients, outcomes have improved, but at the cost of increased treatment plan complexity and planning time. The accurate prediction of dose distributions would…

医学物理 · 物理学 2018-12-03 Dan Nguyen , Troy Long , Xun Jia , Weiguo Lu , Xuejun Gu , Zohaib Iqbal , Steve Jiang

A new method of experimental verification of radial dose distribution models using solid state thermoluminescent (TL) detectors LiF:Mg,Cu,P has been recently proposed. In this work the method was applied to verify the spatial distribution…

仪器与探测器 · 物理学 2014-01-28 W. Gieszczyk , P. Bilski , P. Olko , B. Obryk

The personal (or active) electronic dosimeters (PEDs) are devices used to determine the individual exposure to ionizing radiations and they are employed in hospitals, research laboratories and nuclear power plants. The PDOZ project is a…

Resistors from mobile phones, usually located near the human body, are considered as individual dosimeters of ionizing radiation in emergency situations. The resistors contain Al2O3, which is optically stimulated luminescence (OSL) material…

仪器与探测器 · 物理学 2014-02-24 Anna Mrozik , Barbara Marczewska , Pawel Bilski , Wojciech Gieszczyk

We present an indirect signal processing-based measurement method for biological quantities in humans that cannot be directly measured. We develop the method by focusing on estimating hepatic enzyme and drug transporter activity through…

定量方法 · 定量生物学 2021-01-01 Yoko Franchetti , Thomas D. Nolin , Franz Franchetti

Ion-induced cell killing has been reported to depend on the irradiation dose but also on the projectile parameters. In this paper we focus on two approaches developed and extensively used to predict cell survival in response to ion…

生物物理 · 物理学 2009-07-15 M. Beuve , A. Colliaux , D. Dabli , D. Dauvergne , B. Gervais , G. Montarou , E. Testa

Introduction: Real-time dosimetry of surface doses in electron beams has not been widely established yet. Plastic scintillation detectors (PSD) promise high spatial resolution and real-time dosimetry with minimum perturbation of the…

Radiotherapy is part of the treatment of over 50% of cancer patients. Its efficacy is limited by the radiotoxicity to the healthy tissue. FLASH-RT is based on the biological effect that ultra-high dose rates (UHDR) and very short treatment…

The Dice Similarity Coefficient (DSC) is the current de facto standard to determine agreement between a reference segmentation and one generated by manual / auto-contouring approaches. This metric is useful for non-spatially important…

医学物理 · 物理学 2024-10-29 Lucas McCullum , Kareem A. Wahid , Barbara Marquez , Clifton D. Fuller

Radiation therapy aims to deliver the prescribed amount of dose to a tumour at the same time as sparing the surrounding tissues as much as possible. In charged particle therapy, delivering the prescribed dose is equivalent to delivering the…

医学物理 · 物理学 2018-03-05 Simona Giordanengo , Marco Donetti
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