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Lithography is fundamental to integrated circuit fabrication, necessitating large computation overhead. The advancement of machine learning (ML)-based lithography models alleviates the trade-offs between manufacturing process expense and…

计算机视觉与模式识别 · 计算机科学 2023-04-11 Guojin Chen , Zehua Pei , Haoyu Yang , Yuzhe Ma , Bei Yu , Martin D. F. Wong

Light-field imaging is an emerging paradigm in biomedical optics, offering the unique ability to capture volumetric information in a single snapshot by encoding both the spatial and angular components of light. Unlike conventional…

光学 · 物理学 2025-09-30 Ruixuan Zhao , Xuanwen Hua , Woongjae Baek , Zhaoqiang Wang , Shu Jia , Liang Gao

Optical coherence tomography angiography (OCTA) has been established as a powerful tool for investigating vascular diseases and is expected to become a standard of care technology. However, its widespread clinical usage is hindered by…

医学物理 · 物理学 2021-09-10 Si Chen , Kan Lin , Linbo Liu

Optical coherence tomography (OCT) is widely used for diagnosing and monitoring retinal diseases, such as age-related macular degeneration (AMD). The segmentation of biomarkers such as layers and lesions is essential for patient diagnosis…

计算机视觉与模式识别 · 计算机科学 2025-09-26 Botond Fazekas , Guilherme Aresta , Philipp Seeböck , Julia Mai , Ursula Schmidt-Erfurth , Hrvoje Bogunović

We present a novel method for characterizing the microstructure of a material from volumetric datasets such as 3D image data from computed tomography (CT). The method is based on a new statistical model for the distribution of voxel…

材料科学 · 物理学 2021-01-06 Elise Otterlei Brenne , Vedrana Andersen Dahl , Peter Stanley Jørgensen

We apply a recently developed framework for analyzing the convergence of stochastic algorithms to the general problem of large-scale nonconvex composite optimization more generally, and nonconvex likelihood maximization in particular. Our…

最优化与控制 · 数学 2024-01-25 D. Russell Luke , Steffen Schultze , Helmut Grubmüller

In this paper, we consider visualization of displacement fields via optical flow methods in elastographic experiments consisting of a static compression of a sample. We propose an elastographic optical flow method (EOFM) which takes into…

数值分析 · 数学 2021-03-29 Ekaterina Sherina , Lisa Krainz , Simon Hubmer , Wolfgang Drexler , Otmar Scherzer

Speckle is an intrinsic pattern in optical coherence tomography (OCT) that obscures fine image features and degrades effective resolution. In this study, we propose a numerical speckle reduction method based on the dispersed scatterer model…

Electron ptychography describes a family of algorithms which are used to enable the reconstruction of complex specimen transmission functions of a sample in order to obtain both phase and amplitude information, as applied within the realms…

光学 · 物理学 2025-03-17 L. Clark , P. D. Nellist

Super-resolution light microscopy overcomes the physical barriers due to light diffraction, allowing for the observation of otherwise indistinguishable subcellular entities. However, the specific acquisition conditions required by…

Coherent Diffractive Imaging is a lensless technique that allows imaging of matter at a spatial resolution not limited by lens aberrations. This technique exploits the measured diffraction pattern of a coherent beam scattered by periodic…

Ultrasound-based elasticity imaging is a non-invasive technique for estimating tissue stiffness fields from displacement fields obtained by comparing ultrasound signals before and after compression. While recent deep learning approaches…

医学物理 · 物理学 2026-01-22 Heekyu Kim , Hugon LEe , Minwoo Park , Seunghwa Ryu

We introduce a framework for the reconstruction of the amplitude, phase and polarisation of an optical vector-field using calibration measurements acquired by an imaging device with an unknown linear transformation. By incorporating…

We examine the interaction of multigrid methods and shape optimization in appropriate shape spaces. Our aim is a scalable algorithm for application on supercomputers, which can only be achieved by mesh-independent convergence. The impact of…

最优化与控制 · 数学 2021-04-12 Martin Siebenborn , Kathrin Welker

Major biological discoveries have been made by interrogating living organisms with light. However, the limited penetration of unscattered photons within biological tissues severely limits the depth range covered by optical methods.…

All-optical image processing offers a high-speed, energy-efficient alternative to conventional electronic systems by leveraging the wave nature of light for parallel computation. However, traditional optical processors rely on bulky…

光学 · 物理学 2026-03-17 Linzhi Yu , Haobijam J. Singh , Jesse Pietila , Humeyra Caglayan

Optical Coherence Tomography (OCT) is the primary imaging modality for detecting pathological biomarkers associated to retinal diseases such as Age-Related Macular Degeneration. In practice, clinical diagnosis and treatment strategies are…

计算机视觉与模式识别 · 计算机科学 2019-07-17 Thomas Kurmann , Pablo Márquez-Neila , Siqing Yu , Marion Munk , Sebastian Wolf , Raphael Sznitman

Optical approaches have made great strides towards the goal of high-speed, energy-efficient computing necessary for modern deep learning and AI applications. Read-in and read-out of data, however, limit the overall performance of existing…

A brief review is presented of the scaling of complex fluids, polymers and polyelectrolytes in solution and in confined geometry, in thermodynamical, structural and rheology properties using equilibrium and nonequilibrium dissipative…

软凝聚态物质 · 物理学 2016-12-06 Armando Gama Goicochea

In this paper, we consider the problem of estimating the internal displacement field of an object which is being subjected to a deformation, from Optical Coherence Tomography (OCT) images before and after compression. For the estimation of…

数值分析 · 数学 2020-12-30 Ekaterina Sherina , Lisa Krainz , Simon Hubmer , Wolfgang Drexler , Otmar Scherzer