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We propose an analytical approach to solving the diffusion-convection equations governing oxygen transport in the human placenta. We show that only two geometrical characteristics of a placental cross-section, villi density and the…

定量方法 · 定量生物学 2015-02-05 A. S. Serov , C. Salafia , M. Filoche , D. S. Grebenkov

During pregnancy, oxygen diffuses from maternal to fetal blood through villous trees in the placenta. In this paper, we simulate blood flow and oxygen transfer in feto-placental capillaries by converting three-dimensional representations of…

The primary exchange units in the human placenta are terminal villi, in which fetal capillary networks are surrounded by a thin layer of villous tissue, separating fetal from maternal blood. To understand how the complex spatial structure…

组织与器官 · 定量生物学 2019-09-12 Alexander Erlich , Gareth A. Nye , Paul Brownbill , Oliver E. Jensen , Igor L. Chernyavsky

Across mammalian species, solute exchange takes place in complex microvascular networks. In the human placenta, the primary exchange units are terminal villi that contain disordered networks of fetal capillaries and are surrounded…

The villi and crypts of the gastrointestinal tract increase the effective surface area of the intestinal mucosa, potentially enhancing nutrient absorption. It is commonly assumed that this is their primary function, and that a higher villi…

Flux of rigid or soft particles (such as drops, vesicles, red blood cells, etc.) in a channel is a complex function of particle concentration, which depends on the details of induced dissipation and suspension structure due to hydrodynamic…

This study is focused on measuring the densities of the excited molecular oxygen species, O$_{2}(\text{a}^{1}\Delta_{\text{g}})$ and O$_{2}(\text{b}^{1}\Sigma_{\text{g}}^{+})$, produced in a COST atmospheric pressure plasma jet using a…

Purpose: To study placental function - both perfusion and an oxygenation surrogate (T2*)-simultaneously and quantitatively in-vivo. Methods: 15 pregnant women were scanned on a 3T MR scanner. For perfusion measurements, a velocity selective…

The umbilical cord plays a critical role in delivering nutrients and oxygen from the placenta to the fetus through the umbilical vein, while the two umbilical arteries carry deoxygenated blood with waste products back to the placenta.…

组织与器官 · 定量生物学 2025-10-27 Tianran Wan , Edward D. Johnstone , Shier Nee Saw , Oliver E. Jensen , Igor L. Chernyavsky

The structure of solid oxygen has been studied at pressures from 50 to 140~GPa using static structure search methods and molecular dynamics simulations with density functional theory and a hybrid exchange functional. Several crystalline…

材料科学 · 物理学 2023-09-26 Sabri F. Elatresh , V. Askarpour , S. A. Bonev

We employ a resolvent-based methodology to estimate velocity and pressure fluctuations within turbulent channel flows at friction Reynolds numbers of approximately 180, 550 and 1000 using measurements of shear stress and pressure at the…

流体动力学 · 物理学 2021-10-04 Filipe R. Amaral , André V. G. Cavalieri , Eduardo Martini , Peter Jordan , Aaron Towne

An oxidation process is simulated for a bundle of metal tubes in a cross-flow. A fluid flow is governed by the incompressible Navier-Stokes equations. To describe the transport of oxygen, the corresponding convection-diffusion equation is…

计算工程、金融与科学 · 计算机科学 2017-08-15 Alexander G. Churbanov , Oleg Iliev , Valery F. Strizhov , Petr N. Vabishchevich

Understanding the diffusion of oxygen vacancies in oxides under different external stimuli is crucial for the design of ion-based electronic devices, improve catalytic performance, etc. In this manuscript, using an external electric field…

材料科学 · 物理学 2018-07-04 Lucía Iglesias , Andrés Gómez , Martí Gich , Francisco Rivadulla

Both fluid and particle models are commonly used to simulate streamer discharges. In this paper, we quantitatively study the agreement between these approaches for axisymmetric and 3D simulations of positive streamers in air. We use a…

等离子体物理 · 物理学 2021-12-14 Zhen Wang , Anbang Sun , Jannis Teunissen

In this paper, we develop a pulsatile compartmental model of the Fontan circulation and use it to explore the effects of a fenestration added to this physiology. A fenestration is a shunt between the systemic and pulmonary veins that is…

组织与器官 · 定量生物学 2022-06-23 Zan Ahmad , Lynn H. Jin , Daniel J. Penny , Craig G. Rusin , Charles S. Peskin , Charles Puelz

We study the behavior of the pulse waves of water into a flexible tube for application to blood flow simulations. In pulse waves both fluid friction and wall viscosity are damping factors, and difficult to evaluate separately. In this…

In biological transport mechanisms such as insect respiration and renal filtration, fluid travels along a leaky channel allowing exchange with systems exterior the the channel. The channels in these systems may undergo peristaltic pumping…

流体动力学 · 物理学 2015-11-05 Gregory Herschlag , Jian-Guo Liu , Anita T. Layton

In radiotherapy, the dose-volume histogram (DVH) curve is an important means of evaluating the clinical feasibility of tumor control and side effects in normal organs against actual treatment. Fractionation, distributing the amounts of…

医学物理 · 物理学 2024-09-05 Yusuke Anetai , Jun'ichi Kotoku

Diffusion models are important in tissue engineering as they enable an understanding of molecular delivery to cells in tissue constructs. As three-dimensional (3D) tissue constructs become larger, more intricate, and more clinically…

组织与器官 · 定量生物学 2015-12-22 Richard J. McMurtrey

A comprehensive analysis is presented for the diffusivity of oxygen defects and oxygen self-diffusion in ThO$-2$. The migration energy and diffusivity of oxygen defects with nominal charges have been investigated using density functional…

材料科学 · 物理学 2025-10-21 Maniesha Singh , Anter El-Azab
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