相关论文: Microrheology with Optical Tweezers: Measuring the…
Microrheology is a branch of rheology having the same principles as conventional bulk rheology, but working on micron length scales and micro-litre volumes. Optical tweezers have been successfully used with Newtonian fluids for rheological…
Important aspects in the field of microrheology are the studies of the viscosity of fluids within structures with micron dimensions and fluid samples where only microlitre volumes are available. We have quantitatively investigated the…
Two-point microrheology measurements from widely separated colloidal particles approach the bulk viscosity of the host medium more reliably than corresponding single point measurements. In addition, active microrheology offers the advantage…
We demonstrate an optical system that can apply and accurately measure the torque exerted by the trapping beam on a rotating birefringent probe particle. This allows the viscosity and surface effects within liquid media to be measured…
Many wormlike micellar systems exhibit appreciable shear thinning due to shear induced alignment. As the micelles get aligned introducing directionality in the system, the viscoelastic properties are no longer expected to be isotropic. An…
We present an experimental procedure to perform broadband microrheological measurements with optical tweezers. A generalised Langevin equation is adopted to relate the time-dependent trajectory of a particle in an imposed flow to the…
Viscosity is an important property of out-of-equilibrium systems such as active biological materials and driven non-Newtonian fluids, and for fields ranging from biomaterials to geology, energy technologies and medicine. However,…
It has been argued [Tassieri, \textit{Soft Matter}, 2015, \textbf{11}, 5792] that linear microrheology with optical tweezers (MOT) of living systems ``\textit{is not an option}'', because of the wide gap between the observation time…
Microrheology, the study of fluids on micron length-scales, promises to reveal insights into cellular biology, including mechanical biomarkers of disease and the interplay between biomechanics and cellular function. Here a…
We employ multiple sinusoid modulated optical tweezers to measure the frequency dependent rheological parameters of a linear viscoelastic fluid over five decades of frequency in a single shot, hitherto not achieved using active…
Bulk rheological properties of viscoelastic fluids have been extensively studied in macroscopic shearing geometries. However, little is known when an active microscopic probe is used to locally perturb them far from the linear-response…
The dynamics of solute flow in the microscopic chamber can be studied with optical tweezers. A method based on the metallic microbeads trapped in the focused optical vortex beam is proposed. This annular beam of a twisted wavefront exerts…
Optical tweezers have been successfully adopted as exceptionally sensitive transducers for microrheology studies of complex 'fluids'. Despite the general trend, a similar approach cannot be adopted for microrheology studies of 'gel-like'…
A method to measure the viscosity of liquids at microscales is presented. It uses a thin glass fiber fixed on the tip of the cantilever of an extremely low noise Atomic Force Microscope (AFM), which accurately measures the cantilever…
The recent development of opto-mechano-fluidic resonators has provided -- by harnessing photon radiation pressure -- a new microfluidics platform for the optical sensing of fluid density and bulk modulus. Here we show that fluid viscosity…
Optical and acoustical trapping has been established as a tool for holding and moving microscopic particles suspended in a liquid in a contact-free and non-invasive manner. Opposed to standard microscopic imaging where the probe is fixated,…
Optical tweezers are highly versatile laser traps for neutral microparticles, with fundamental applications in physics and in single molecule cell biology. Force measurements are performed by converting the stiffness response to…
In recent years there has been an explosive development of interest in the measurement of forces at the microscopic level, such as within living cells, as well as the properties of fluids and suspensions on this scale, using optically…
Calibration of optically trapped particles in-vivo has been complicated given the frequency dependence and spatial inhomogeneity of the cytoplasmic viscosity, and the requirement of accurate knowledge of the medium refractive index.…
We simulate macroscopic shear experiments in active nematics and compare them with microrheology simulations where a spherical probe particle is dragged through an active fluid. In both cases we define an effective viscosity: in the case of…