相关论文: Dynamic Variation in Protein-Small Molecule Intera…

A detailed treatment of an electro-optical trap for polar molecules, realized by embedding an optical trap within a uniform electrostatic field, is presented and the trap's properties analyzed and discussed. The electro-optical trap offers…

Optical interfaces for quantum emitters are a prerequisite for implementing quantum networks. Here, we couple single molecules to the guided modes of an optical nanofiber. The molecules are embedded within a crystal that provides…

Optical molecular sensing techniques are often limited by the refractive index change associated with the probed interactions. In this work, we present a closed form analytical model to estimate the magnitude of optical refractive index…

In living organisms, proteins and peptides are often under the influence of mechanical forces, especially in confined spaces such as membrane channels, ribosome exit tunnel, or proteasome gate. Due to the directional nature of proteins as…

Within a closed system, physical interactions are reciprocal. However, the effective interaction between two entities of an open system may not obey reciprocity. Here, we describe a non-reciprocal interaction between nanoparticles which is…

The manipulation of nanoscale matter has the potential to revolutionize a variety of fields across nanoscience and technology. Here, we demonstrate experimentally and characterize numerically a device that combines the benefits of…

Optical tweezers have revolutionized particle manipulation at the micro- and nanoscale, playing a critical role in fields such as plasmonics, biophysics, and nanotechnology. While traditional optical trapping methods primarily rely on…

The optical trapping of polymeric nanofibers and the characterization of the rotational dynamics are reported. A strategy to apply a torque to a polymer nanofiber, by tilting the trapped fibers using a symmetrical linear polarized Gaussian…

Complex DNA topological structures, including polymer loops, are frequently observed in biological processes when protein molecules simultaneously bind to several distant sites on DNA. However, the molecular mechanisms of formation of these…

Optomechanics, which explores the fundamental coupling between light and mechanical motion, has made important advances in both exploring and manipulating macroscopic mechanical oscillators down to the quantum level. However, dynamical…

The internal dynamics of macro-molecular systems is characterized by widely separated time scales, ranging from fraction of ps to ns. In ordinary molecular dynamics simulations, the elementary time step dt used to integrate the equation of…

Accurate quantification of protein-nanoparticle interactions is essential for applications in nanobiotechnology, nanomedicine, and drug delivery. Motivated by recent computational and experimental work, we combine coarse-grained united-atom…

Investigations of molecular bonds between single molecules and molecular complexes by the dynamic force spectroscopy are subject to large fluctuations at nanoscale and possible other aspecific binding, which mask the experimental output.…

Collisions between cold molecules are essential for studying fundamental aspects of quantum chemistry, and may enable formation of quantum degenerate molecular matter by evaporative cooling. However, collisions between trapped, naturally…

Optical trapping, also known as optical tweezing or optical levitation, is a technique that uses highly focused laser beams to manipulate micro- and nanoscopic particles. In optical traps driven by high-energy pulses, material non-linearity…

Metal nanoantennas enable the manipulation of light emission and detection at the single photon level by confining light into very small volumes. Emitters coupled to these plasmonic structures are thus ideal candidates for usage in quantum…

Time-division multiplexing presents an attractive opportunity to probe multi-colloidal interactions in optical traps at short time-scales. In this paper, we demonstrate a stroboscopic system capable of arbitrary control of multiple trapped…

Fast detection and characterization of single nanoparticles such as viruses, airborne aerosols and colloidal particles are considered to be particularly important for medical applications, material science and atmospheric physics. In…

We study the effect of a coupling between two motor domains in highly-processive motor protein complexes. A simple stochastic discrete model, in which the two parts of the protein molecule interact through some energy potential, is…

Understanding protein dynamics are essential for deciphering protein functional mechanisms and developing molecular therapies. However, the complex high-dimensional dynamics and interatomic interactions of biological processes pose…