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We provide an overview of current approaches to DNA-based storage system design and accompanying synthesis, sequencing and editing methods. We also introduce and analyze a suite of new constrained coding schemes for both archival and random…

Molecular and morphological characters, as important parts of biological taxonomy, are contradictory but need to be integrated. Organism's image recognition and bioinformatics are emerging and hot problems nowadays but with a gap between…

计算机视觉与模式识别 · 计算机科学 2022-06-29 Jiewen Xiao , Wenbin Liao , Ming Zhang , Jing Wang , Jianxin Wang , Yihua Yang

Website reliability labels underpin almost all research in misinformation detection. However, misinformation sources often exhibit transient behavior, which makes many such labeled lists obsolete over time. We demonstrate that Search Engine…

社会与信息网络 · 计算机科学 2024-06-19 Peter Carragher , Evan M. Williams , Kathleen M. Carley

Statistical matching methods are widely used in the social and health sciences to estimate causal effects using observational data. Often the objective is to find comparable groups with similar covariate distributions in a dataset, with the…

应用统计 · 统计学 2021-01-19 Felix Bestehorn , Maike Bestehorn , Christian Kirches

When an individual's DNA is sequenced, sensitive medical information becomes available to the sequencing laboratory. A recently proposed way to hide an individual's genetic information is to mix in DNA samples of other individuals. We…

信息论 · 计算机科学 2024-11-05 Kayvon Mazooji , Roy Dong , Ilan Shomorony

Despite outstanding performance on public benchmarks, face recognition still suffers due to domain mismatch between training (source) and testing (target) data. Furthermore, these domains are not shared classes, which complicates domain…

计算机视觉与模式识别 · 计算机科学 2021-04-09 Chun-Hsien Lin , Bing-Fei Wu

Identifying gene splicing is a core and significant task confronted in modern collaboration between artificial intelligence and bioinformatics. Past decades have witnessed great efforts on this concern, such as the bio-plausible splicing…

定量方法 · 定量生物学 2024-06-19 Qi-Jie Li , Qian Sun , Shao-Qun Zhang

Citation matching is a challenging task due to different problems such as the variety of citation styles, mistakes in reference strings and the quality of identified reference segments. The classic citation matching configuration used in…

数字图书馆 · 计算机科学 2019-06-12 Behnam Ghavimi , Wolfgang Otto , Philipp Mayr

In this work we seek clusters of genomic words in human DNA by studying their inter-word lag distributions. Due to the particularly spiked nature of these histograms, a clustering procedure is proposed that first decomposes each…

应用统计 · 统计学 2021-01-13 Ana Helena Tavares , Jakob Raymaekers , Peter J. Rousseeuw , Paula Brito , Vera Afreixo

Learning DAG structures from purely observational data remains a long-standing challenge across scientific domains. An emerging line of research leverages the score of the data distribution to initially identify a topological order of the…

机器学习 · 计算机科学 2026-01-27 Vy Vo , He Zhao , Trung Le , Edwin V. Bonilla , Dinh Phung

Mutual correlation between segments of DNA or protein sequences can be detected by Smith-Waterman local alignments. We present a statistical analysis of alignment of such sequences, based on a recent scaling theory. A new fidelity measure…

凝聚态物理 · 物理学 2007-05-23 Rolf Olsen , Terence Hwa , Michael Lassig

We develop topological methods for analyzing difference topology experiments involving 3-string tangles. Difference topology is a novel technique used to unveil the structure of stable protein-DNA complexes involving two or more DNA…

几何拓扑 · 数学 2016-01-20 Isabel K. Darcy , John Luecke , Mariel Vazquez

We consider the design of a pattern recognition that matches templates to images, both of which are spatially sampled and encoded as temporal sequences. The image is subject to a combination of various perturbations. These include ones that…

计算机视觉与模式识别 · 计算机科学 2009-05-22 Ivan Tyukin , Tatiana Tyukina , Cees van Leeuwen

Traditional Genetic Algorithms (GAs) mating schemes select individuals for crossover independently of their genotypic or phenotypic similarities. In Nature, this behaviour is known as random mating. However, non-random schemes - in which…

神经与进化计算 · 计算机科学 2009-09-30 C. M. Fernandes , J. J. Merelo , A. C. Rosa

The problem of motif detection can be formulated as the construction of a discriminant function to separate sequences of a specific pattern from background. In computational biology, motif detection is used to predict DNA binding sites of a…

基因组学 · 定量生物学 2010-12-10 Qing Zhou

Measuring biases of vision systems with respect to protected attributes like gender and age is critical as these systems gain widespread use in society. However, significant correlations between attributes in benchmark datasets make it…

计算机视觉与模式识别 · 计算机科学 2021-03-26 Chandan Singh , Guha Balakrishnan , Pietro Perona

Discrete mixture models provide a well-known basis for effective clustering algorithms, although technical challenges have limited their scope. In the context of gene-expression data analysis, a model is presented that mixes over a finite…

统计方法学 · 统计学 2012-11-12 Michael A. Newton , Lisa M. Chung

Peaks in the probabilities of loops or bubbles, helical segments, and unzipping ends in melting DNA are found in this article using a peak finding method that maps the hierarchical structure of certain energy landscapes. The peaks indicate…

生物大分子 · 定量生物学 2007-05-23 E. Tostesen

We explore the large-scale behavior of nucleotide compositional strand asymmetries along human chromosomes. As we observe for 7 of 9 origins of replication experimentally identified so far, the (TA+GC) skew displays rather sharp upward…

We present a method to determine Fashion DNA, coordinate vectors locating fashion items in an abstract space. Our approach is based on a deep neural network architecture that ingests curated article information such as tags and images, and…

信息检索 · 计算机科学 2016-09-09 Christian Bracher , Sebastian Heinz , Roland Vollgraf