相关论文: A novel radioguided surgery technique exploiting $…
The development of the $\beta^-$ based radio-guided surgery aims to extend the technique to those tumours where surgery is the only possible treatment and the assessment of the resection would most profit from the low background around the…
Purpose: A radio-guided surgery technique with beta- -emitting radio-tracers was suggested to overcome the effect of the large penetration of gamma radiation. The feasibility studies in the case of brain tumors and abdominal neuro-endocrine…
The $\beta^-$ based radio-guided surgery overcomes the corresponding $\gamma$ technique in case the background from healthy tissues is relevant. It can be used only in case a radio-tracer marked with $^{90}$Y is available since the current…
The recent interest in beta- radionuclides for radio-guided surgery derives from the feature of the beta radiation to release energy in few millimeters of tissue. Such feature can be used to locate residual tumors with a probe located in…
A novel radio guided surgery (RGS) technique for cerebral tumors using $\beta^{-}$ radiation is being developed. Checking the availability of a radio-tracer that can deliver a $\beta^{-}$ emitter to the tumor is a fundamental step in the…
A radio-guided surgery technique exploiting $\beta^-$ emitters is under development. It aims at a higher target-to-background activity ratio implying both a smaller radiopharmaceutical activity and the possibility of extending the technique…
In surgical oncology, it is challenging for surgeons to identify lymph nodes and completely resect cancer even with pre-operative imaging systems like PET and CT, because of the lack of reliable intraoperative visualization tools.…
This review focuses on the physics of Gamma Ray Bursts probed through their radio afterglow emission. Even though radio band is the least explored of the afterglow spectrum, it has played an important role in the progress of GRB physics,…
Surgical tumor resection aims to remove all cancer cells in the tumor margin and at centimeter-scale depths below the tissue surface. During surgery, microscopic clusters of disease are intraoperatively difficult to visualize and are often…
GRETA, the Gamma-Ray Energy Tracking Array, is an array of highly-segmented HPGe detectors designed to track gamma-rays emitted in beam-physics experiments. Its high detection efficiency and state-of-the-art position resolution make it…
Around half of all cancer patients, world-wide, will receive some form of radiotherapy (RT) as part of their treatment. And yet, despite the rapid advance of high-throughput screening to identify successful chemotherapy drug candidates,…
Searches of new physics beyond the Standard Model (SM) performed at low energy frontiers are complementary to experiments carried out at high energy colliders. Among the methods for testing the SM and beyond at low energies are the…
PET is an established medical diagnostic imaging method. Continuous improvements are aimed at refining image reconstruction, reducing the amount of radioactive tracer and combining with targeted therapy. TOF-PET provides the localization of…
Short gamma-ray bursts (GRBs) are explosive transients caused by binary mergers of compact objects containing at least one neutron star. Multi-wavelength afterglow observations provide constraints on the physical parameters of the jet, its…
Material screening for identifying low-energy electron emitters and alpha-decaying isotopes is now a prerequisite for rare-event searches (e.g., dark-matter direct detection and neutrinoless double-beta decay) for which surface…
Nuclear $\beta$ decay, a sensitive probe of nuclear structure and weak interactions, has become a precision test bed for physics beyond the Standard Model, driven by recent advances in spectrometric techniques. Here we introduce tomographic…
Gamma-ray bursts (GRBs) are extremely energetic events at cosmological distances. They provide unique laboratory to investigate fundamental physical processes under extreme conditions. Due to extreme luminosities, GRBs are detectable at…
Intensity-modulated proton therapy (IMPT) employs proton radiation rather than conventional X-rays to treat cancerous tumors. This approach offers significant advantages by minimizing the radiation exposure of surrounding healthy tissue,…
The degree of beaming in Gamma-Ray Bursts (GRBs) is currently unknown. The uncertainty in the gamma-ray beaming angle, theta, leaves the total energy release (proportional to theta^2) and the event rate per galaxy (proportional to…
Cancer remains a significant health challenge worldwide, with a new diagnosis occurring every two minutes in the UK. Surgery is one of the main treatment options for cancer. However, surgeons rely on the sense of touch and naked eye with…